Vulcan 10mg Injection is a medicine used in the treatment of a condition called methemoglobinemia. Methemoglobinemia is a blood disorder in which an abnormal amount of methemoglobin is produced. This medicine reduces the methemoglobin to hemoglobin. This helps in the treatment of the condition.
Vulcan 10mg Injection is given as an injection by a doctor or a nurse. Do not self-administer this medicine at home. Get the complete dose of the injection for maximum benefits. Do not stop it suddenly without consulting the doctor. If your condition does not improve, let your doctor know. They may initiate an alternative treatment.
Some common side effects of this medicine include pain in extremities, chromaturia (abnormal coloration of urine), taste change, feeling hot, dizziness, sweating, nausea, skin discoloration, and headaches. It may also cause confusion and disturbances in vision, do not drive or do anything that requires mental focus until you know how this medicine affects you.
Before taking this medicine, let your doctor know if you have any medical conditions such as blood disorders such as anemia or a history of allergic reactions with this medicine. Let your doctor also know about all the other medicines that you are taking. Pregnant and breastfeeding women should consult their doctors before taking this medicine as it may cause harmful effects to the developing baby.
Uses of Vulcan Injection
Methaemoglobinemia
Benefits of Vulcan Injection
In Methaemoglobinemia
Methemoglobinemia is a blood disorder where an abnormal form of hemoglobin reduces the blood’s ability to carry oxygen, causing symptoms like bluish skin, shortness of breath, and fatigue. Vulcan 10mg Injection helps restore normal hemoglobin, improving oxygen delivery in the body. This relieves symptoms and helps patients recover from the condition more effectively.
Side effects of Vulcan Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Vulcan
Headache
Nausea
Myoclonus
Decreased potassium level in blood
Diarrhea
Decreased magnesium level in blood
Seizure disorders
How to use Vulcan Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Vulcan Injection works
Methylene blue acts as a reducing agent to reduce methemoglobin to hemoglobin. It is reduced to leucomethylene blue in the red blood cells of our body, by combining with a chemical nicotinamide adenine dinucleotide phosphate (NADPH), in the presence of an enzyme called NADPH reductase. Leucomethylene blue reduces methemoglobin to hemoglobin and restores the oxygen carrying capacity of hemoglobin. This helps in the treatment of Methemoglobinemia.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Vulcan 10mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
The safety of Vulcan 10mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Vulcan 10mg Injection during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Vulcan 10mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Vulcan 10mg Injection can cause confusion, dizziness, and possible eye disturbances. Do not drive until you know how the medicine affects you.
Kidney
CAUTION
Vulcan 10mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver
CAUTION
Vulcan 10mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.
What if you forget to take Vulcan Injection?
If you miss a dose of Vulcan 10mg Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
Vulcan 10mg Injection is prescribed for the treatment of methemoglobinemia (blood disorders).
Consult your doctor immediately if you notice any change in mental status or neuromuscular symptoms with or without gastrointestinal symptoms.
It is advisable to take protective measures against exposure to light, because phototoxicity (sensitivity to light) may occur after administration of Vulcan 10mg Injection.
Vulcan 10mg Injection is prescribed for the treatment of methemoglobinemia (blood disorders).
Consult your doctor immediately if you notice any change in mental status or neuromuscular symptoms with or without gastrointestinal symptoms.
It is advisable to take protective measures against exposure to light, because phototoxicity (sensitivity to light) may occur after administration of Vulcan 10mg Injection.
Fact Box
Chemical Class
Benzothiazines
Habit Forming
No
Therapeutic Class
OTHERS
Action Class
Monoamine Oxidase (MAO) Inhibitors
FAQs
What is Vulcan 10mg Injection used for?
Vulcan 10mg Injection is used to treat acquired methemoglobinemia (when blood cannot carry oxygen well), helping restore normal oxygen levels in the body in adults and children.
Who should not receive Vulcan 10mg Injection?
People with G6PD deficiency (a red blood cell enzyme problem) must not receive Vulcan 10mg Injection because it can cause severe hemolytic anemia (breakdown of red blood cells). Also, anyone with a severe allergy to methylene blue or similar dyes should not receive it.
Why is there a serious warning with Vulcan 10mg Injection and antidepressants or some pain medicines?
Vulcan 10mg Injection can dangerously raise serotonin (a brain chemical) when used with serotonergic drugs such as SSRIs/SNRIs (many antidepressants), MAOIs, linezolid, some opioids, or dextromethorphan (cough medicine). This can lead to serotonin syndrome (agitation, fever, fast heartbeat, stiff muscles), which is life‑threatening.
What are emergency warning signs after receiving Vulcan 10mg Injection?
After receiving Vulcan 10mg Injection, get help right away if you develop a severe allergic reaction (swelling, trouble breathing, hives), signs of serotonin syndrome (confusion, high fever, shaking, stiff muscles, diarrhea), chest pain, seizures, or signs of anemia (extreme tiredness, pale skin, yellow eyes/skin, dark urine).
Can Vulcan 10mg Injection affect oxygen monitors?
Yes. Vulcan 10mg Injection can make pulse oximeters (finger oxygen clips) read low by mistake. Doctors may use blood tests instead to check oxygen levels after the injection.
I have kidney or liver problems. Does that change anything about Vulcan 10mg Injection?
Kidney or liver problems can make Vulcan 10mg Injection stay longer in your body, so doctors may use fewer doses and monitor you longer for side effects.
What if the first dose of Vulcan 10mg Injection does not fix the problem?
If methemoglobinemia does not improve after two doses of Vulcan 10mg Injection, doctors will consider other treatments instead of giving more methylene blue.
Can Vulcan 10mg Injection change lab tests or cause staining?
Yes. Vulcan 10mg Injection can turn urine blue and interfere with urine dipstick tests that use a blue color change. It may also temporarily color skin or body fluids.
Are there any heart or brain risks associated with Vulcan 10mg Injection?
High doses of Vulcan 10mg Injection can cause blood pressure changes, fast heartbeat, breathing issues, or seizures. That is why dosing is carefully controlled, and you are monitored during and after treatment.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Methylene blue [FDA Label]. Marseille, France: Provepharm Life Solutions SA; 2016. [Accessed 29 Jul. 2021] (online) Available from: