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Tritanrix HB Injection is a combination of four medicines used in the prevention of tetanus, diphtheria, and pertussis. It is also used in the prevention of hepatitis B infections. It stimulates the immune system to act against microorganisms to prevent such infections.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 12 Aug 2026 | 01:04 AM (IST)
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Tritanrix HB Injection image
Tritanrix HB Injection image

Product introduction

Tritanrix HB Injection is administered by a healthcare professional. It may cause redness, soreness, and swelling at the site of infusion. This usually goes away with time. It can be taken by patients irrespective of age.

Tritanrix HB Injection is generally well tolerated by patients and is also safe in children, however, it has a few side effects such as swelling, pain, and fever. Before receiving this vaccine, it is important to inform your doctor if you have any preexisting medical conditions.

Benefits of Tritanrix HB Injection

Prevention of Tetanus
Tetanus is a serious bacterial infection that affects the nervous system and causes muscles throughout the body to become stiff and tighten. Tritanrix HB Injection helps prevent tetanus infection. It helps the immune system to produce antibodies to fight against tetanus infection. However, it does not provide lifelong protection. Children need to get a booster shot at 11 or 12 years of age. Adults need a booster shot every 10 years after that. It is advisable to consult your doctor for complete information regarding vaccination schedules.
Prevention of Pertussis
Pertussis (often called whooping cough) is an infection of the airways that can occur at any age but mostly affects infants and young children. The infection causes uncontrollable coughing that can make it difficult to breathe. Tritanrix HB Injection gives protection from pertussis. Consult your doctor for complete information regarding vaccination schedules.
Prevention of Diphtheria
Diphtheria is a bacterial infection that causes pain and swelling in the throat. This might cause difficulty in breathing. It might also damage the heart, kidneys and nerves. Tritanrix HB Injection gives protection against diphtheria. It is recommended to get your child vaccinated against diphtheria starting at 6 weeks through 6 years. It is advisable to consult your doctor for complete information regarding vaccination schedules.
Prevention of Hepatitis B infection
Hepatitis B is an infection of the liver caused by the Hepatitis B virus (HBV). It can spread from person to person through blood, semen or other body fluids. It can cause mild illness lasting a few weeks, or it can lead to a serious, lifelong illness. Tritanrix HB Injection is given to prevent hepatitis B infection. It is recommended for all infants and children of 6 weeks through 6 years of age. It is advisable to consult your doctor for complete information regarding vaccination schedules.

Side effects of Tritanrix HB Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tritanrix HB
  • Injection site redness
  • Swelling
  • Pain
  • Fever

How to use Tritanrix HB Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Tritanrix HB Injection works

Tritanrix HB Injection is a combination of four vaccines. They help develop immunity by initiating a mild infection. This type of infection does not cause illness but stimulates the body's immune system to produce antibodies (proteins) to protect against any future infections.

Quick tips

  • Tritanrix HB Injection is used for the immunization of infants and children of 6 weeks through 6 years of age against diphtheria, tetanus, pertussis, and hepatitis B.
  • If you are severely ill, you should probably wait until you recover. Your doctor can advise you on this.
  • You can apply an ice pack on the injection site if you experience pain and redness. 

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tritanrix HB Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Tritanrix HB Injection during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Tritanrix HB Injection during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Tritanrix HB Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Tritanrix HB Injection in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Tritanrix HB Injection in patients with liver disease.

Fact Box

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Glaxo SmithKline Pharmaceuticals Ltd
Address: Dr. Annie Besant Road, Mumbai - 400 030

Vendor Details

Country of origin: India
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