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Tris Tablet is a combination medicine used in the treatment of schizophrenia (a mental disorder in which a person develops unreal thoughts and behavior). It alters the thoughts and elevates the mood, improving the person’s ability to think, feel and behave.
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 22 May 2026 | 06:23 PM (IST)
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 22 May 2026 | 06:23 PM (IST)
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General Information
The content is shown in English



Product introduction
Tris Tablet may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.
Some common side effects of this medicine include nausea, constipation, dryness in mouth, sedation, abnormal heart rhythm, urinary retention, blurred vision, and nervousness. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you.
Before taking it, inform your doctor if you are suffering from thyroid or kidney problems, epilepsy, Parkinson’s disease, glaucoma, or any heart problems. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.
Some common side effects of this medicine include nausea, constipation, dryness in mouth, sedation, abnormal heart rhythm, urinary retention, blurred vision, and nervousness. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you.
Before taking it, inform your doctor if you are suffering from thyroid or kidney problems, epilepsy, Parkinson’s disease, glaucoma, or any heart problems. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.
Uses of Tris Tablet
Benefits of Tris Tablet
Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Tris Tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Tris Tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.
Side effects of Tris Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tris
- Nausea
- Constipation
- Dryness in mouth
- Sedation
- Weight gain
- Arrhythmia (irregular heartbeats)
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Urinary retention
- Increased prolactin level in blood
- Dizziness
- Blurred vision
- Nervousness
How to use Tris Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tris Tablet may be taken with or without food.
How Tris Tablet works
Tris Tablet is a combination of three medicines: Trihexyphenidyl, Thioridazine and Trifluoperazine. Trihexyphenidyl is an anticholinergic which works on the nervous system and corrects some of the chemical imbalances that cause Parkinson's disease and certain side effects occurring during antipsychotic treatment. Thioridazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood. Trifluoperazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.
All substitutes for Tris Tablet
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- Tris Tablet is used for the treatment of schizophrenia.
- It is better to take Tris Tablet at night as this medicine may produce drowsiness or sleepiness.
- Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
- Inform your doctor if you are taking any antidepressants or medicines for heart problems, high blood pressure, or asthma.
- If you have diabetes, you will be asked to monitor your blood glucose level regularly as Tris Tablet may affect the levels of sugar in your blood.
Safety advice

Alcohol
CAUTION
Alcohol should be used with caution while taking Tris Tablet.

Pregnancy
CONSULT YOUR DOCTOR
Tris Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding
CONSULT YOUR DOCTOR
Tris Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving
UNSAFE
Tris Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Tris Tablet make u feel dizzy, drowsy or can cause blurred vision. This may affect your driving ability.
Tris Tablet make u feel dizzy, drowsy or can cause blurred vision. This may affect your driving ability.

Kidney
CAUTION
Tris Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver
CAUTION
Tris Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
However, the use of Tris Tablet is not considered safe in patients with liver disease as per the available data.
However, the use of Tris Tablet is not considered safe in patients with liver disease as per the available data.
Fact Box
Habit Forming
No
Therapeutic Class
NEURO CNS
References
- Trihexyphnidyl. Huddersfield, West Yorkshire: Genus Pharmaceuticals; 2011 [revised 18 Dec. 2018]. [Accessed 23 Apr. 2019] (online) Available from:
- Trifluoperazine. Leeds, Yorkshire: Rosemont Pharmaceuticals Limited; 2008 [revised 27 Nov. 2018]. [Accessed 23 Apr. 2019] (online) Available from:
- Trihexyphnidyl. Huddersfield, West Yorkshire: Genus Pharmaceuticals; 2011 [revised 18 Dec. 2018]. [Accessed 23 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: A N Pharmacia
Address: 315, 3rd Floor DLF Tower B, Jasola, Delhi -110044
Address: 315, 3rd Floor DLF Tower B, Jasola, Delhi -110044
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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