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Triglow Cream is a medicine that contains a combination of medicines that is used to treat melasma. It helps in quick skin renewal. It provides relief from redness, swelling, and itching.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 22 Apr 2026 | 05:28 PM (IST)
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Product introduction

Triglow Cream should be used in the dose and duration as advised by your doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. Do not use this medicine more than the recommended dose. Inform your doctor if you have known allergies to this medicine.


Common side effects of this medicine include burning, irritation, itching, and redness at the site of application. It may also cause dry skin, acne, and itching. If any of these side effects bother you or get worse, consult your doctor.


Inform your doctor if you are pregnant or are suffering from any other disease. Caution is needed while breastfeeding; this medicine is not recommended unless advised by your doctor. Do not use this medicine if you have a history of allergic reactions to any of the ingredients in this product.

Uses of Triglow Cream

  • Melasma

Side effects of Triglow Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Triglow
  • Burning sensation
  • Dryness
  • Erythema (skin redness)
  • Itching
  • Skin peeling
  • Dry skin
  • Acne

How to use Triglow Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Triglow Cream works

Triglow Cream is a combination of three medicines: Hydroquinone, Tretinoin and Fluocinolone acetonide which treat melasma (dark spots on skin). The exact way this triple combination improves melasma is not fully known. Hydroquinone helps reduce melanin (skin pigment), tretinoin promotes skin cell turnover, and fluocinolone acetonide reduces skin inflammation.

All substitutes for Triglow Cream

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Along with applying Triglow Cream, wear long-sleeved clothing, sunglasses, or a hat whenever you step outside in the hot sun for better protection.
  • Do not cover the area being treated with airtight dressings unless instructed by a doctor.
  • Use moisturizer regularly to overcome skin dryness during the course of treatment.
  • You may also use certain safe cosmetics (after consulting with your doctor) to lighten pigmentation.
  • Before using Triglow Cream, inform your doctor if you have any skin problems or are applying any other medicines to your skin.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

UNSAFE
Triglow Cream is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Triglow Cream may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Triglow Cream is prescribed for the short-term treatment of moderate to severe melasma, a dark, patchy discoloration on the face. It helps lighten those spots when used along with sun protection, avoiding sunlight.
No. Triglow Cream is only approved for facial melasma. It has not been proven safe or effective for other pigment problems like freckles, age spots, or acne marks.
No. Triglow Cream is for short-term use only. Once your dark patches improve, your doctor may suggest stopping and switching to other maintenance options. Using it continuously may increase the risk of skin side effects.
While you are on Triglow Cream therapy, you should avoid direct sunlight exposure, UV lamps, always apply sunscreen (SPF 30 or higher), wear protective clothing, do not use on broken or irritated skin, avoid using harsh soaps, astringents, products that cause dryness, or peeling.
Triglow Cream may rarely trigger serious allergic or asthma-like reactions in sensitive people. If you experience swelling, wheezing, or severe itching, stop using it and get medical help immediately.
Exogenous ochronosis is a blue-black darkening of the skin that can happen with long-term use of hydroquinone (present in Triglow Cream). It is rare but may be permanent. If your skin starts getting darker instead of lighter, stop using the medicine and contact your doctor.
Yes, with prolonged or excessive use, the corticosteroid (fluocinolone) present in Triglow Cream can cause skin thinning or, in rare cases, hormonal (adrenal) effects. Use it exactly as directed, usually once daily, only for a short time.
Serious side effects of Triglow Cream may include severe burning, swelling, blistering of the skin, worsening pigmentation, signs of infection, skin thinning, and any allergic reaction (rash, difficulty breathing, facial swelling). Seek immediate medical attention if you notice any symptoms.
Triglow Cream has not been well-studied in very dark skin types (Fitzpatrick V-VI). Over-bleaching, uneven lightening may occur. Your dermatologist can guide you on whether it is appropriate.
Melasma often comes back after stopping Triglow Cream. To maintain results, continue sun protection, and follow your doctor’s advice on safer long-term maintenance options.

Fact Box

Habit Forming

No

Therapeutic Class

DERMA
100% genuine products
100% genuine products
Safe & secure payments
Safe & secure payments
No contact delivery
No contact delivery
Fully sanitized facilities
Fully sanitized facilities

User feedback

Once A Day
100%
Melasma
84%
Others
14%
Hyperpigmentation
2%
Average
42%
Poor
32%
Excellent
26%
No Side Effect
53%
Application site reactions (burning, irritation, itching and redness)
41%
Skin irritation
6%
With or without food
57%
Empty stomach
21%
With food
21%
Average
55%
Not Expensive
24%
Expensive
21%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Glenmark Pharmaceuticals Ltd
Address: Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Triglow Cream. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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