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18 Feb 2020 | 05:25 PM (IST)
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Overview

Introduction

Trigabantin 300 Tablet is a combination medicine used in the treatment of neuropathic pain. It calms the damaged or overactive nerves by acting on the brain, thereby decreasing the sensation of pain. It also helps in the regeneration of damaged nerves in the body.

Trigabantin 300 Tablet should be taken on an empty stomach. It is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as this is a habit-forming medicine. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor.

Some common side effects of this medicine include dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. The side effects are mild in nature and get improve with time. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.

Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Trigabantin Tablet

Side effects of Trigabantin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Trigabantin

  • Dizziness
  • Sleepiness
  • Tiredness
  • Uncoordinated body movements

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Sleepiness
    If the medicine is making you drowsy during the day, stop what you are doing and sit or lie down until you feel better. You can also consider taking a nap. Physical exercises such as walking may be helpful. Do not drink alcohol, as it will make you feel more tired. Avoid driving or operating heavy equipment when you are feeling drowsy. This problem usually goes away as your body gets used to the medicine. However, if it does not, ask your doctor if you can take your medicine at bedtime or whether the dose can be reduced.
  • Coping with Tiredness
    Make sure you rest and drink plenty of fluids. Eat a well-balanced diet to keep your energy levels up. Do not drink too much alcohol. Do not drive or use tools or machinery until you feel better. Other things that can help include doing some gentle exercise every day, prioritizing and pacing your activities and having a short nap if you need to. If you are still having problems after a week, speak to your doctor, as they may want to change you to a different type of medicine.

How to use Trigabantin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trigabantin 300 Tablet is to be taken empty stomach.

How Trigabantin Tablet works

Trigabantin 300 Tablet is a combination of three medicines: Gabapentin, Methylcobalamin/Mecobalamin and Alpha Lipoic Acid. Gabapentin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Methylcobalamin/Mecobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Alpha Lipoic Acid is a naturally occurring fatty acid which has a protective effect on brain and nerve tissue. Together, they relieve neuropathic pain (pain from damaged nerves).

Safety Advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Trigabantin 300 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Trigabantin 300 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Trigabantin 300 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Baby should be monitored for excessive sleepiness and weight gain.
Driving
UNSAFE
Trigabantin 300 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Trigabantin 300 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Trigabantin 300 Tablet may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Trigabantin 300 Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Trigabantin 300 Tablet may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Trigabantin 300 Tablet
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Quick Tips

  • You have been prescribed Trigabantin 300 Tablet for treating and preventing nerve pain.
  • It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. 
  • Avoid consuming alcohol when taking Trigabantin 300 Tablet, as it may cause excessive sleepiness.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Habit Forming
No

Patient Concerns

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Most of the times when I get excited or have orgasm I feel pain in my testis and around it .
Dr. Pranay Gandhi
Sexology
hi PATIENT neuropathic pain mostly. take tablet emanzen d 1 bd
Burning sensation in sole ,penile region regularly No spot at penile area but constant burning sensation at sole and penile area No relief from amoxicillin,ceprofloxin doxycyclene Period :last 14 days
Dr. Pranay Gandhi
Sexology
that may be a neuropathic pain. do u have high bp or diabetes. take tablet pregama m 1 od for 15 days
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FAQs

Q. What is Trigabantin?

Trigabantin is a combination of three medicines: Gabapentin, Methylcobalamin and Alpha lipoic acid. This medicine is useful in the treatment of nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain, thereby decreasing the pain sensation. It also helps in the regeneration of damaged nerves in the body.

Q. How to manage weight gain associated with the use of Trigabantin?

Trigabantin can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing increased weight. Try to eat a healthy balanced diet without increasing your portion size (per-meal intake). Do not eat foods that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits and sweets. If you feel hungry between meals, avoid eating junk foods and eat fruits, vegetables and low-calorie foods. Regular exercise will also help maintain your weight. If you keep good eating habits and exercise regularly, you might not gain any weight.

Q. Can the use of Trigabantin cause sleepiness or drowsiness?

Yes, Trigabantin may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities until you know how the medicine affects you. Inform your doctor if you experience such episodes while taking this medicine.

Q. Are there any serious side effects associated with the use of Trigabantin?

Serious side effects with Trigabantin are uncommon and rare. However, it may cause serious side effects like an allergic reaction, suicidal thoughts or swelling of limbs (hands, legs or feet). Stop taking Trigabantin and contact your doctor if you have any signs of these serious side effects. Signs of allergic reaction include swelling of your face, mouth, lips, gums, tongue and neck. You may even have trouble in breathing, skin rash, hives (raised bumps) or blisters. Pay attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings which may be a symptom of suicidal thoughts.

Q. How long will Trigabantin take to act?

An initial benefit with Trigabantin may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see the full benefits. It may take even longer in some patients.

Q. What if I take too much of this drug by mistake?

Contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteadiness while walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.

Q. Will a higher than the recommended dose of Trigabantin be more effective?

No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Q. How often should I see the doctor?

You may need to see your doctor regularly if you have started taking Trigabantin. However, if the recommended doses do not relieve your symptoms or you experience some unwanted side effect that affects your routine activities, consult your doctor.

Q. What are the instructions for the storage and disposal of Trigabantin?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Can I stop taking Trigabantin when my pain is relieved?

No, you should not stop taking Trigabantin even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Trigabantin, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain, and sweating. You may need to gradually taper the use of Trigabantin before you stop the medication completely.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Gabapentin. Barnstaple, Devon: Accord-UK Ltd.; 2005 [revised 26 Oct. 2017] [Accessed 22 Apr. 2019] (online) Available from:External Link
  2. MedlinePlus. Vitamin B12. [Accessed 22 Apr. 2019] (online) Available from:External Link
  3. Drugs.com. Alpha Lipolic Acid. [Accessed 22 Apr. 2019] (online) Available from:External Link

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