Tresiba 100 Units/ml Penfill (3ml Each) is an ultra long-acting type of insulin used to treat types 1 and 2 diabetes mellitus in both adults and children. It provides a steady level of insulin in the body for an entire day and helps control blood sugar levels. This helps to prevent complications of diabetes.
Tresiba 100 Units/ml Penfill (3ml Each) can be prescribed by itself or along with a fast-acting type of insulin or other diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. You should use this medicine regularly as per the dose advised to get the most benefit. It is usually taken once daily at the same time every day. However, on occasions when administration at the same time of the day is not possible, it may be taken at a different time of the day. Always ensure that there is a minimum gap of 8 hours between doses. If you stop taking it your blood sugar levels may rise very high and put you at risk of serious complications. It is only a part of the treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor.
The most common side effects of this medicine is low blood sugar levels (hypoglycemia). To prevent hypoglycemia, it is important to always inject only the correct dose of medicine, have regular meals, and monitor your blood sugar levels regularly. Drinking excessive alcohol can also lead to a fall in your blood sugar levels. Other side effects include injection site reactions like redness, swelling, or hard lumps (lipohypertrophy). Some people may also gain weight while taking insulin.
Do not use this medicine when you have low blood sugar levels (hypoglycemia). Tell your doctor if you have ever had kidney, liver, or heart problems before starting treatment. Pregnant or breastfeeding women should also consult their doctor before using it.
Tresiba 100 Units/ml Penfill (3ml Each) is a long-acting insulin that provides effective blood sugar control for people with diabetes. Its ultra-long duration of action allows for more flexibility in dosing times and ensures stable insulin levels over 24 hours or more. This helps reduce the risk of blood sugar fluctuations, particularly low blood sugar episodes (hypoglycemia), especially overnight. It offers the convenience of once-daily dosing and can be adjusted to fit individual needs, making it a valuable option for those managing both Type 1 and Type 2 diabetes.
Side effects of Tresiba Solution for Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tresiba
Auto-antibody formation
Headache
Injection site reactions (pain, swelling, redness)
Severe hypoglycemia
Nasopharyngitis (inflammation of the throat and nasal passages)
Upper respiratory tract infection
How to use Tresiba Solution for Injection
Your doctor or nurse will guide you how to use this medicine.
How Tresiba Solution for Injection works
Tresiba 100 Units/ml Penfill (3ml Each) is a long-acting insulin that provides consistent, all-day sugar control. It works like your body's natural insulin. Insulin facilitates reuptake of sugar in muscle and fat cells and also suppresses the production of sugar in the liver.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Tresiba 100 Units/ml Penfill (3ml Each).
Pregnancy
SAFE IF PRESCRIBED
Tresiba 100 Units/ml Penfill (3ml Each) is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Tresiba 100 Units/ml Penfill (3ml Each) is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Tresiba 100 Units/ml Penfill (3ml Each) should be used with caution in patients with kidney disease. Dose adjustment of Tresiba 100 Units/ml Penfill (3ml Each) may be needed. Please consult your doctor. Frequent and regular monitoring of blood glucose levels is advised.
Liver
CAUTION
Tresiba 100 Units/ml Penfill (3ml Each) should be used with caution in patients with liver disease. Dose adjustment of Tresiba 100 Units/ml Penfill (3ml Each) may be needed. Please consult your doctor. Frequent and regular monitoring of blood glucose levels is advised.
What if you forget to take Tresiba Solution for Injection?
If you miss a dose of Tresiba 100 Units/ml Penfill (3ml Each) take it as soon as you remember. Do not take two doses of Tresiba 100 Units/ml Penfill (3ml Each) within 8 hours of each other.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
This medicine is injected under the skin. It needs to be injected once daily, at the same time every day.
Injection below the skin of the abdomen results in faster absorption than other injection sites.
Injection sites must be rotated to prevent hard lumps from developing at one site.
Do not use it if the preparation is no longer clear and colorless or if it contains particles.
Hypoglycemia (low blood sugar level) is a common side effect. Always carry some sugary food or fruit juice with you so that you can take it when you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremors, and anxiety.
Opened vials/cartridges stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator (2°C–8°C).
Fact Box
Chemical Class
Insulin analogue
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Action Class
Insulin analogues- long acting
Patient concerns
Iam using Tresiba insulin the same is costly is there any substitute for tresiba
Dr. Sanjay Bhatt
Physician
Substitute medicine is available. But needs complete medical history and sugar level chart for priscribing medicine. So you needs to consult doctor near by or visit our clinic as wants to see the patient
Fasting 140 PP 190 to 240. Taking novamex 50 - 25 mmg twice day and Tresiba insulin degludec - 20 mg once a day
Dr. Sanjay Bhatt
Physician
A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED. ALWAYS IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you SHOULD not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
My diabetes is not control and my wait is loosing again so pls suggest that Tresiba insulin, evion LC ,gemer pl 2 , gemer 1 , istamet 50/500 medilda this tablet is taken by me thanks
Dr. Sanjay Bhatt
Physician
Weight loosing is because of diabetes. Needs to take medicines regularly and do exercise regularly. Try to keep sugar level in normal limits.
Patient is on insulin tresiba 20 units (bed time) and oral medicine trajenta duo 2.5/500 twice a day. He is also undergoing treatment of liver chhirosis with strict diet plan of low salt with high protien. Issue is that his fasting comes in range of 80-90 but before lunch it raises upto 220-240 and after dinner PP comes in range 280-300. Pl suggest. Last Hba1c was 7.1
Dr. Sanjay Bhatt
Physician
Confirm about your diet failure. Dose adjustment needed in the oral medicine you are taking. So discuss with your doctor
I am Type 2 Diabetic on Insulin regime I a taking 30u Tresiba in the night and Humalog 16u thrice a day with Reclimet and Lipagyl twice a day, Rosacur, Adlip and cilacar sartel h once a day, My problem is that after Breakfast and Lunch but not after Dinner the sugar level shoots up above 250 and then I take shots of Humalog or Apidra to bring it down and in an attempt to bring it down it goes even upto 60. Please advice how should I manage Insulin Regards
Dr. Ashwin Porwal
Internal Medicine
this cant be treated on a chatting platformyou should consult a physician in person for this
A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
What were the side-effects while using Tresiba 100 Units/ml Penfill (3ml Each)?
No Side Effec*
80%
Injection sit*
10%
Hypoglycemia *
10%
*No Side Effect, Injection site allergic reaction, Hypoglycemia (low blood glucose level)
How do you take Tresiba Solution for Injection?
With food
48%
With or witho*
29%
Empty stomach
24%
*With or without food
Please rate Tresiba 100 Units/ml Penfill (3ml Each) on price
Expensive
72%
Average
25%
Not Expensive
3%
FAQs
What is Tresiba 100 Units/ml Penfill (3ml Each)?
Tresiba 100 Units/ml Penfill (3ml Each) is an ultralong-acting type of insulin used to control high blood sugar in adults and children (as young as 1 year of age) with type 1 and type 2 diabetes mellitus. Tresiba 100 Units/ml Penfill (3ml Each) works like the insulin that is normally produced by the body and helps move sugar from the blood into other body tissues where it is used for energy production. Also, it stops the liver from producing more sugar and this helps to normalize the blood sugar levels.
How is Tresiba 100 Units/ml Penfill (3ml Each) administered?
Tresiba 100 Units/ml Penfill (3ml Each) is injected just below the skin (subcutaneously). Your doctor will train you on the correct method and the areas (abdomen or stomach, thighs, arms, hips, or buttocks) where you should inject it. It is advised that the site of injection should be changed within the chosen area of skin, for every dose. For example, if you have been advised to inject it into the skin of your stomach, avoid puncturing the same point on your stomach every day. Rather, inject the needle at a site that is slightly away, say around 1cm, from the previous injection. You can also consider switching sides while injecting, like choosing the right side on one day and the left side on the next day. This way, you can reduce the complications associated with repeated injections in the same site such as thickening of the fat tissue below the skin known as lipodystrophy, irritation, pain etc. After one to two weeks, you should move to another area of your body (eg. from the stomach to the arms or thighs) as advised by your doctor. Consult your doctor if you face any problems while injecting Tresiba 100 Units/ml Penfill (3ml Each).
Are Insulin glargine and Tresiba 100 Units/ml Penfill (3ml Each) the same?
Insulin glargine and Tresiba 100 Units/ml Penfill (3ml Each) are both man-made versions of human insulin used to manage diabetes, however, they are different in some aspects. Insulin glargine is a long-acting insulin that typically lasts about 24 hours and helps maintain adequate blood sugar control for an entire day. Whereas, Tresiba 100 Units/ml Penfill (3ml Each) is an ultralong-acting insulin that can last longer (up to 42 hours) and helps control blood sugar levels for more than a day.
Is Tresiba 100 Units/ml Penfill (3ml Each) better than insulin detemir?
Both Tresiba 100 Units/ml Penfill (3ml Each) and insulin detemir are long-acting insulins with almost similar effectiveness and safety. The only difference is that Tresiba 100 Units/ml Penfill (3ml Each) has the longest duration of action (more than 40 hours) and this helps to maintain steady blood sugar levels throughout this duration. Some studies have reported that Tresiba 100 Units/ml Penfill (3ml Each) may have a slightly lesser risk of hypoglycemia.
Can Tresiba 100 Units/ml Penfill (3ml Each) be used in combination with other diabetes medicines?
Tresiba 100 Units/ml Penfill (3ml Each) can be safely used in combination with other diabetes medicines or fast-acting insulins if prescribed by the doctor. Take it in the dose and duration advised by your doctor to get maximum benefit. However, taking thiazolidinediones (TZDs), like pioglitazone, with Tresiba 100 Units/ml Penfill (3ml Each) may cause heart failure in some people. This can happen even if you have never had heart failure or heart problems. In case you already have heart failure, it may get worse on taking TZDs with Tresiba 100 Units/ml Penfill (3ml Each). Let your doctor know about all the other medicines, particularly any other diabetes medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you have or ever had any heart problems.
What should I avoid while taking Tresiba 100 Units/ml Penfill (3ml Each)?
Your doctor will advise certain lifestyle changes and you must adhere to them. Stay active and exercise regularly. Avoid missing meals and monitor your blood sugar levels. You may consult a dietician and follow a diet chart that suits you best. Do not drive or operate heavy machinery until you know how Tresiba 100 Units/ml Penfill (3ml Each) affects you. Do not drink alcohol as it may cause some undesirable side effects like dizziness. Tell your doctor about all the other medicines that you are taking as they may affect your dosage.
Can Tresiba 100 Units/ml Penfill (3ml Each) be used alone?
Tresiba 100 Units/ml Penfill (3ml Each) can help with daily management of diabetes. However, you may still need to use short-acting insulin to treat spikes in your blood sugar levels and diabetic ketoacidosis (a dangerous buildup of acids in your blood).
Is Tresiba 100 Units/ml Penfill (3ml Each) basal insulin?
Yes, Tresiba 100 Units/ml Penfill (3ml Each) is basal insulin. There are three types of basal insulin currently available: Glargine, Detemir, and Degludec. The pharmacies sell these under different brand names. Basal insulin is a slow-acting type of insulin. People take it between mealtimes and before bedtime to control blood sugar outside of eating.
How does basal insulin work?
Long-acting insulins are also called basal or background insulins. They keep working in the background to keep your blood sugar under control throughout your daily routine. They’re absorbed into your body over a 24-hour period. Therefore, they keep blood sugar levels lowered for longer than short-acting insulins do.
Can Tresiba 100 Units/ml Penfill (3ml Each) cause weight gain?
Yes, Tresiba 100 Units/ml Penfill (3ml Each) may cause weight gain in some patients. This may be due to the anabolic effect of insulin which promotes the storage of glucose and fat.
Can Tresiba 100 Units/ml Penfill (3ml Each) raise your blood sugar?
No, Tresiba 100 Units/ml Penfill (3ml Each) by itself does not raise your blood sugar. However, if you stop taking Tresiba 100 Units/ml Penfill (3ml Each), miss a dose, or take a dose lower than what is prescribed, your blood sugar levels may rise. Furthermore, if the person has any other condition along with diabetes, especially infections, stress, irregular meals, or reduced activity levels, it may also lead to high blood sugar levels. As a result, their requirement for Tresiba 100 Units/ml Penfill (3ml Each) may increase further. Consult your doctor to know about any dose changes if you have been facing any of these issues or if your blood sugar levels are not controlled.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Insulin degludec injection [Prescribing Information]. Bagsvaerd, Denmark: Novo Nordisk A/S; 2016. [Accessed 17 Oct. 2017] (online) Available from:
Tresiba [Summary of Product Characteristics]. Bagsværd, Denmark: Novo Nordisk A/S; 2017. [Accessed 08 Oct. 2021] (online) Available from:
Insulin Degludec [Product Monograph]. Ontario, Canada: Novo Nordisk Canada Inc; 2019. [Accessed 08 Oct. 2021] (online) Available from:
Zinman B, Philis-Tsimikas A, Cariou B, et al. Insulin degludec versus insulin glargine in insulin-naive patients with type 2 diabetes: A 1-year, randomized, treat-to-target trial (BEGIN Once Long). Diabetes Care. 2012;35(12):2464-71. [Accessed 08 Oct. 2021] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 12 Mar. 2019] (online) Available from:
Insulin degludec [Summary of Product Characteristics]. Bagsværd, Denmark: Novo Nordisk A/S; 2017. [Accessed 05 Jul. 2023]. (online) Available from:
Country of origin: Denmark Expires on or after: July, 2025
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