Overview
Uses and benefits
Side effects
How to use
How drug works
Safety advice
Missed dose
All substitutes
Quick tips
Fact box
Patient concerns
User feedback
FAQs

Author Details

Written By

Dr. Subita Alagh

BDS

Reviewed By

Dr. Sachin Gupta

MD Pharmacology, MBBS

Last updated

13 Feb 2026 | 02:52 AM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Home>Topnac P>topnac p tablet

Topnac P Tablet

Prescription Required

Marketer

Systopic Laboratories Pvt Ltd

SALT COMPOSITION

Aceclofenac (100mg) + Paracetamol (325mg)

Storage

Store below 30°C

35% cheaper alternative available with same salt composition

Click here to view all substitutes

Product introduction

Topnac P Tablet is a pain-relieving medicine. It reduces pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Topnac P Tablet should be taken with or without food. It should be taken regularly as advised by your doctor. Your doctor may change the dose and time between doses according to your pain level and needs. Do not take more or use it for a longer duration than recommended by your doctor.

Some of the common side effects of this medicine include nausea, dizziness and diarrhoea. You should let your doctor know if any of these side effects bother you or if they do not go away with time. Your doctor may help you with ways to reduce or prevent these side effects by prescribing an alternative medicine or adjusting the dose.

Topnac P Tablet may not be suitable for everyone. Before taking it, let your doctor know if you have any problems with your heart, kidneys, or liver or have stomach ulcers. Also, tell your doctor about all the other medicines you take to ensure they are safe. Pregnant and breastfeeding mothers should consult their doctors before using Topnac P Tablet.

Uses of Topnac P Tablet

Pain relief

Benefits of Topnac P Tablet

In Pain relief

Topnac P Tablet is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. Some of the conditions in which Topnac P Tablet is used are rheumatoid arthritis, osteoarthritis, muscle pain, back pain, toothache, or pain in the ear and throat. Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Topnac P Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Topnac P

Nausea
Diarrhea
Increased liver enzymes

How to use Topnac P Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Topnac P Tablet may be taken with or without food.

How Topnac P Tablet works

Topnac P Tablet is a combination of two medicines: Aceclofenac and Paracetamol. These medicines work by blocking the action of chemical messengers responsible for pain, fever and inflammation (redness and swelling).

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Topnac P Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Topnac P Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CONSULT YOUR DOCTOR

Topnac P Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Topnac P Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Topnac P Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Topnac P Tablet is not recommended in patients with severe kidney disease.

Liver

UNSAFE

Topnac P Tablet is unsafe to use in patients with liver disease and should be avoided.
However, the use of Topnac P Tablet is not recommended in patients with severe liver disease and active liver disease.

What if you forget to take Topnac P Tablet?

If you miss a dose of Topnac P Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Topnac P Tablet

₹3.54/Tablet

acimol 100mg/325mg Tablet

Leeford Healthcare Ltd

₹2.29/tablet

35% cheaper

Movexx Plus Tablet

Cipla Ltd

₹3.36/tablet

5% cheaper

Aldigesic P 100mg/325mg Tablet

Alkem Laboratories Ltd

₹4.84/tablet

37% costlier

Acemiz Plus Tablet

Lupin Ltd

₹8.28/tablet

134% costlier

Acenext P 100mg/325mg Tablet

Cadila Pharmaceuticals Ltd

₹3.99/tablet

13% costlier

View all substitutes

Quick tips

You have been prescribed this combination medicine to relieve pain and inflammation.
Take it with food to avoid getting an upset stomach.
Do not take Topnac P Tablet with any other medicine containing paracetamol (drugs for pain, fever, cough, and cold) without first asking your doctor.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Topnac P Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
If you have muscle pain, your doctor might advise you to undergo physiotherapy and take Topnac P Tablet to relieve the pain.
Inform your doctor if you have a history of stomach ulcers before taking this medicine.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Patient concerns

What r Painkiller may be used in pregnancy .topnac p and zintac is safe to use in pregnancy

Dr. Suman Rao

Obstetrics and Gynaecology

Zintac can be taken but it's not a pain killer. For pain killer prescription see a gynae nearby

One of my teeth is sensitive. It some times pains

Dr. Abhijit Gambhir

Dental Surgery

sensitivity has many causative factors for relief of pain you can take pain killers it will give temporary relief

User feedback

Patients taking Topnac P Tablet

Once A Day

60%

Twice A Day

40%

What are you using Topnac P Tablet for?

Pain relief

75%

Others

Headache

Fever

How much was the improvement?

Excellent

39%

Poor

33%

Average

28%

What were the side-effects while using Topnac P Tablet?

No Side Effec*

60%

Nausea

20%

Vomiting

20%

*No Side Effect

How do you take Topnac P Tablet?

With food

60%

With or witho*

40%

*With or without food

Please rate Topnac P Tablet on price

Not Expensive

75%

Average

25%

FAQs

What is Topnac P Tablet?

Topnac P Tablet is a combination of two medicines: Aceclofenac and Paracetamol. It relieves pain and inflammation by lowering the levels of chemical substances in the body that cause them.

Can I stop taking Topnac P Tablet when my pain is relieved?

If you are using the medication for a condition associated with long-term pain, then Topnac P Tablet should be continued for as long as advised by your physician. It can be discontinued if you are using it for short-term pain relief.

Can the use of Topnac P Tablet cause nausea and vomiting?

Yes, the use of Topnac P Tablet can cause nausea and vomiting. Taking it with milk, food, or antacids can prevent nausea. Avoid eating fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small, frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark-colored, strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.

Can the use of Topnac P Tablet cause dizziness?

Yes, using Topnac P Tablet can cause dizziness (feeling faint, weak, unsteady, or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.

Are there any specific contraindications associated with the use of Topnac P Tablet?

The use of Topnac P Tablet is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). It should preferably be avoided in patients with a history of stomach ulcers or patients with active, recurrent stomach ulcers/bleeding. It should also be avoided in patients with a history of heart failure, high blood pressure, and liver or kidney disease.

Can Topnac P Tablet be taken with vitamin B-complex?

Yes, Topnac P Tablet can be taken with vitamin B-complex preparations. While Topnac P Tablet helps relieve pain, vitamin B-complex can help correct the deficiency that might be causing the underlying painful condition.

Show less

Top Rheumatologists

4.7 ★

4.6 ★

4.9 ★

5 ★

MBBS, DNB, MD, Fellowship, Fellowship

4.7 ★

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Furst DE, Ulrich RW, Prakash S, et al. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 621-642.
Grosser T, Smyth EM, FitzGerald GA. Pharmacotherapy of Inflammation, Fever, Pain, and Gout. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 13th ed. New York, NY: McGraw-Hill Education; 2018. pp. 685-709.
Eraas International. Aceclofenac+Paracetamol [Product Information]. [Accessed 14 Aug. 2024] (online) Available from:
Aceclofenac And Paracetamol. Zuventus; [Accessed 14 Aug. 2024] (online). Available from:

Marketer details

Name: Systopic Laboratories Pvt Ltd

Address: 101, Pragati Chambers, Commercial Complex, Ranjit Nagar, New Delhi-110008

Country of origin: India
Expires on or after: November, 2026

A licensed vendor partner from your nearest location will deliver Topnac P Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

MRP₹38.44 8% OFF

₹35.4

Inclusive of all taxes

10.0 tablets in 1 strip

The price displayed is the MRP (inclusive of applicable taxes). Any additional fee (such as shipping fee, handling and/or platform fee etc.) will be clearly disclosed before you complete your purchase.