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Composition for TOLIFAST-D

Tolperisone(150 mg),Diclofenac(50 mg)

food interaction for TOLIFAST-D

alcohol interaction for TOLIFAST-D

pregnancy interaction for TOLIFAST-D

lactation interaction for TOLIFAST-D

There is no data available. Please consult doctor before consuming the drug.
Taking diclofenac with alcohol can increase your risk of stomach bleeding.
Tolifast-d tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Tolperisone(150 mg)


Tolperisone is used to relieve stiffness or rigidity of muscles (muscle spasticity) and muscular contraction (spasm). It is used in the treatment of unusual stiffness of muscle after certain neurological diseases in adults.

How it works

Tolperisone belongs to group of medicines called muscle relaxant. It works by action on central nervous system. It has pain relieving (analgesic) activity too.

Common side effects

Pale red skin, Itchy rash, Rash, Decreased blood pressure, Shortness of breath, Eye swelling, Lip swelling, Itching, Severe systemic reactions, Skin redness, Tachycardia
Diclofenac(50 mg)


Diclofenac is used in the treatment of painful conditions of joints, lower back pain, sprains or bone fractures, inflammation of joints (frozen shoulder, gout), pain and swelling following skeletal muscle, dental and other minor surgeries. It is also used in treatment of migraine.

How it works

Diclofenac belongs to group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the production of a certain chemical substance in the body that causes pain, fever, and inflammation.

Common side effects

Epigastric pain, Renal dysfunction, Stomach ulcer, Bleeding, Toxic epidermal necrolysis, Itching


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Expert advice for TOLIFAST-D

  • Tolperisone tablet should be taken after meals with a glass of water.
  • Do not drive because you may feel sleepy or dizzy while being treated with tolperisone.
  • Women and patients with hypersensitivity to other drugs (e.g., lidocaine) or with a history of allergy may be at a higher risk of hypersensitivity to tolperisone.
Do not start or continue the tolperisone and consult your doctor:
  • If you experience disturbance in attention, fits (epilepsy), blurred vision or muscular weakness.
  • If you experience viral infections at the same time.
  • If you have a history of allergic diseases such as runny nose due to allergy (hay fever), asthma, eczema (atopic dermatitis) with high serum IgE, and pale red, raised, itchy skin rash (urticaria).
  • If you are pregnant or planning to become pregnant or breastfeeding.

Frequently asked questions for TOLIFAST-D


Q. Is tolperisone a steroid, stimulant, or addictive drug?
No, tolperisone is not a steroid, stimulant or addictive drug. It is a muscle relaxant.
Q. Is tolperisone or Synaptol safe?
Tolperisone or Synaptol (brand name of tolperisone) is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Can I take Synaptol with concerta?
 The use of Synaptol with concerta (methylphenidate) should be avoided.

Q. Does Synaptol work for Attention Deficit Disorder (ADD) or Attention Deficit Hyperactivity Disorder (ADHD)?
Use of Synaptol or tolperisone is not approved for Attention Deficit Disorder (ADD) or Attention Deficit Hyperactivity Disorder (ADHD).
Q. Does Synaptol work for adults?
Yes Synaptol is used in the treatment of unusual tightness of muscle after a stroke in adults.
Q. Does Synaptol cause weight loss or weight gain, or suppress appetite?
There is no data about Synaptol causing weight loss or weight gain, or suppress appetite. Please consult your doctor before taking the drug.


Q. Is diclofenac safe?
Diclofenac (also available as voveran, dynapar) is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is diclofenac nephrotoxic?
Diclofenac can interfere with normal kidney function when taken at larger doses for a longer duration. Patients should follow the advice of the doctor regarding its uses.
Q. Is diclofenac safe in asthma?
Diclofenac may worsen the symptoms of asthma in some patients already suffering from asthma. Talk to your doctor before taking diclofenac in asthma.
Q. Is diclofenac banned in India?
Diclofenac is available over-the-counter and it is not banned in India.
Q. Is diclofenac a blood thinner / controlled substance?
Diclofenac is a pain relieving medication and it does not significantly affect the function of platelets in blood; hence it is not a blood thinner. It is not a controlled substance as it does not have the potential for abuse or addiction.
Q. Does diclofenac increase blood pressure?
Diclofenac does not have any effect on blood pressure in normal individuals. However, consult your doctor before taking diclofenac if you are already suffering from high blood pressure or any other heart disease.
Q. Does diclofenac induce sleep?
Diclofenac does not induce sleep.


Content on this page was last updated on 16 June, 2015, by Dr. Varun Gupta (MD Pharmacology)