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Thiossil Plus 325mg/4mg Tablet

Paracetamol (325mg)+ Thiocolchicoside (4mg)
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Thiossil Plus 325mg/4mg Tablet is a combination of two medicines used in the treatment of pain due to muscle spasm. It improves the movement of muscles and provides relief from pain and discomfort associated with muscle spasms.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 19 Dec 2025 | 12:56 PM (IST)
₹139 MRP ₹156.0911% off 
 
 
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Thiossil Plus 325mg/4mg Tablet image
Thiossil Plus 325mg/4mg Tablet image

Product introduction

Thiossil Plus 325mg/4mg Tablet can be taken with or without food. You should take it regularly as advised by your doctor. Do not take more or use it for a longer duration than recommended by your doctor.

Using this medicine can cause some common side effects such as stomach pain, diarrhea, and skin rash. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help with ways to reduce or prevent these side effects.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, or liver. To make sure it is safe for you, let your doctor also know all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using the medicine.

Uses of Thiossil Plus Tablet

  • Pain due to muscle spasm

Benefits of Thiossil Plus Tablet

Pain due to muscle spasm
Thiossil Plus 325mg/4mg Tablet is a combination of a pain reliever and a muscle relaxant. It treats pain due to muscle spasm by relaxing stiff muscles. This in turn reduces discomfort and helps in easy movement. Thiossil Plus 325mg/4mg Tablet works by blocking chemicals in our brain that are responsible for pain sensation and swelling in the muscles. By reducing pain, it improves the quality of your life. Thiossil Plus 325mg/4mg Tablet also helps reduce fever associated with muscular pain.

Side effects of Thiossil Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Thiossil Plus
  • Stomach pain
  • Diarrhea
  • Skin rash

How to use Thiossil Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Thiossil Plus 325mg/4mg Tablet may be taken with or without food.

How Thiossil Plus Tablet works

Thiossil Plus 325mg/4mg Tablet is a combination of two medicines: Paracetamol and Thiocolchicoside, which relieves pain and relax the muscles. Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that are responsible for pain and fever. Thiocolchicoside is a muscle relaxant. It works by acting on the centers in the brain and spinal cord to relieve the muscle stiffness or spasm.

All substitutes for Thiossil Plus 325mg/4mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • You have been prescribed Thiossil Plus 325mg/4mg Tablet to relieve pain due to muscle spasm.
  • It is usually used along with rest and physical therapy.
  • Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first. 

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Thiossil Plus 325mg/4mg Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Thiossil Plus 325mg/4mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Thiossil Plus 325mg/4mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Thiossil Plus 325mg/4mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Thiossil Plus 325mg/4mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Thiossil Plus 325mg/4mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
However, the use of Thiossil Plus 325mg/4mg Tablet is not recommended in patients with severe liver disease and active liver disease.

Frequently asked questions

Thiossil Plus 325mg/4mg Tablet is used to treat pain and muscle spasms caused by musculoskeletal conditions like back pain, neck pain, sprains, strains, and after surgery.
Thiossil Plus 325mg/4mg Tablet should be avoided in people if they are allergic to any ingredient present in it, are suffering from serious liver, kidney, or muscle disorders, or have a history of severe reactions to painkillers or muscle relaxants.
Although they are rare, serious side effects of Thiossil Plus 325mg/4mg Tablet include severe allergic reactions, jaundice, liver dysfunction, and skin rash. Seek medical help if any severe symptoms appear.
Yes, drowsiness or dizziness may occur, so avoid driving or operating machinery until the effects are known.
Thiossil Plus 325mg/4mg Tablet should only be used for children under medical supervision, with proper dosage adjustment. If your child is having pain, consult a doctor before giving any painkiller medicines to them.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cubit Healthcare
Address: 1, Cubit House, 13/369, Panchratna Estate, B/h Ankoor Oil Factory, Opp. Bhagyoday Hotel, Changodar, Ahmedabad-382210 (Guj.) INDIA.

Vendor Details

Country of origin: India
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