Syspride Mps 125mg/10mg Tablet

Cisapride (125mg)+ Methylpolysiloxane (10mg)

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Syspride Mps 125mg/10mg Tablet is a combination medicine used in the treatment of gastroesophageal reflux disease (Acid reflux) by relieving symptoms such as heartburn, indigestion, stomach pain, or irritation. It also promotes easy passage of gas to reduce stomach discomfort.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 03 Aug 2026 | 01:01 AM (IST)

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General Information

Contains

Cisapride (125mg)+ Methylpolysiloxane (10mg)

Marketer

Systopic Laboratories Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Syspride Mps 125mg/10mg Tablet is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are nausea, diarrhea, constipation, stomach pain, runny nose, and headache. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any side effects. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have liver or kidney diseases so that your doctor can prescribe a suitable dose for you.

Uses of Syspride Mps Tablet

Gastroesophageal reflux disease (Acid reflux)

Benefits of Syspride Mps Tablet

Gastroesophageal reflux disease (Acid reflux)
Gastroesophageal reflux disease (GERD) is a condition where stomach acid frequently flows back into the food pipe (esophagus), leading to symptoms like heartburn, chest discomfort, and regurgitation. It occurs when the lower esophageal sphincter weakens or relaxes inappropriately. Syspride Mps 125mg/10mg Tablet helps relieve these symptoms by improving the movement of food through the stomach and reducing acid build-up and gas. This medicine provides relief from discomfort and prevents further irritation of the esophagus.

Side effects of Syspride Mps Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Syspride Mps

Nausea
Diarrhea
Constipation
Stomach pain
Runny nose
Headache

How to use Syspride Mps Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Syspride Mps 125mg/10mg Tablet is to be taken on an empty stomach.

How Syspride Mps Tablet works

Syspride Mps 125mg/10mg Tablet is a combination of two medicines: Cisapride and Methylpolysiloxane. Cisapride is a prokinetic which facilitates the movement of intestines, thereby increasing the frequency of bowel movements, softening stools, and reducing abdominal pain/discomfort. Methylpolysiloxane is an antifoaming medicine which disintegrates gas bubbles and allows easy passage of gas.

Quick tips

Syspride Mps 125mg/10mg Tablet is prescribed to get relief from acidity, heartburn and other discomfort associated with acid reflux.
Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.
Do not take other indigestion remedies (antacids) without consulting your doctor.
Incorporate the following lifestyle changes in order to prevent acidity:
1. Make sure you eat regular meals and drink plenty of water.
2. Avoid spicy and fatty fried food.
3. Lose weight if you are obese.
4. If you are a smoker, consider giving up.
5. Don't drink too much alcohol.
6. Do not go to bed immediately after taking a meal. Sit in a relaxed position for some time for better digestion.
Syspride Mps 125mg/10mg Tablet is prescribed to get relief from acidity, heartburn and other discomfort associated with acid reflux.
Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.
Do not take other indigestion remedies (antacids) without consulting your doctor.
Incorporate the following lifestyle changes in order to prevent acidity:
1. Make sure you eat regular meals and drink plenty of water.
2. Avoid spicy and fatty fried food.
3. Lose weight if you are obese.
4. If you are a smoker, consider giving up.
5. Don't drink too much alcohol.
6. Do not go to bed immediately after taking a meal. Sit in a relaxed position for some time for better digestion.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Syspride Mps 125mg/10mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Syspride Mps 125mg/10mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.

Driving

CONSULT YOUR DOCTOR

It is not known whether Syspride Mps 125mg/10mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Syspride Mps 125mg/10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Syspride Mps 125mg/10mg Tablet is safe to use in patients with liver disease. No dose adjustment is recommended.

Fact Box

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Systopic Laboratories Pvt Ltd
Address: 101, Pragati Chambers, Commercial Complex, Ranjit Nagar, New Delhi-110008

Vendor Details

Country of origin: India

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Gastroprokinetics

Syspride Mps 125mg/10mg Tablet

Syspride Mps 125mg/10mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Syspride Mps Tablet

Benefits of Syspride Mps Tablet

Side effects of Syspride Mps Tablet

How to use Syspride Mps Tablet

How Syspride Mps Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Fact Box

Habit Forming

Therapeutic Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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