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Sylate-M 500 Tablet
Ethamsylate (500mg)+ Mefenamic Acid (500mg)
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Sylate-M 500 Tablet is a combination medicine used in the treatment of bleeding. It works by preventing the breakdown of clots and controls excessive bleeding during menstruation (periods).
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 22 May 2026 | 06:22 PM (IST)
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 22 May 2026 | 06:22 PM (IST)
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10 tablets
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General Information
Contains
Ethamsylate (500mg)+ Mefenamic Acid (500mg)
Marketer
Emcure Pharmaceuticals Ltd
Storage
Store below 30°C
The content is shown in English



Product introduction
Sylate-M 500 Tablet should be taken with food to avoid stomach upset. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better.
It may cause side effects like skin rash, headache, nausea, and loss of appetite. These are usually mild but let your doctor know if they bother you or last more than a few days. Before taking this medicine, let your doctor know if you have liver or kidney problems, or you are pregnant or breastfeeding. It might cause dizziness, if happens better to avoid driving or machinery work. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.
It may cause side effects like skin rash, headache, nausea, and loss of appetite. These are usually mild but let your doctor know if they bother you or last more than a few days. Before taking this medicine, let your doctor know if you have liver or kidney problems, or you are pregnant or breastfeeding. It might cause dizziness, if happens better to avoid driving or machinery work. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.
Uses of Sylate-M Tablet
Benefits of Sylate-M Tablet
Bleeding
Sylate-M 500 Tablet helps normal blood clotting, which reduces the bleeding during menstruation. It helps to prevent excessive loss of blood, stops bleeding and enhances the healing process. Sylate-M 500 Tablet blocks certain chemicals that causes pain and thus gives relief. This helps prevent complications of excessive bleeding such as hemorrhage. It is advisable to use the medicine as prescribed for it to be effective.
Sylate-M 500 Tablet helps normal blood clotting, which reduces the bleeding during menstruation. It helps to prevent excessive loss of blood, stops bleeding and enhances the healing process. Sylate-M 500 Tablet blocks certain chemicals that causes pain and thus gives relief. This helps prevent complications of excessive bleeding such as hemorrhage. It is advisable to use the medicine as prescribed for it to be effective.
Side effects of Sylate-M Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sylate-M
- Skin rash
- Headache
- Nausea
- Vomiting
- Heartburn
- Indigestion
- Diarrhea
- Loss of appetite
How to use Sylate-M Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sylate-M 500 Tablet should be taken with or after food.
How Sylate-M Tablet works
Sylate-M 500 Tablet is a combination of two medicines: Ethamsylate and Mefenamic Acid. Ethamsylate is an antifibrinolytic. It works by preventing the breakdown of clots and controls excessive bleeding during menstruation (periods). Mefenamic Acid is a non-steroidal anti-inflammatory drug (NSAID) which blocks the production of certain chemical messengers (prostaglandins) that cause pain and inflammation (redness and swelling).
Quick tips
- Sylate-M 500 Tablet helps reduce blood loss.
- Take it with a light snack or meal to avoid stomach upset.
- Stick to simple meals and avoid spicy rich food in order to avoid feeling sick (nausea).
Safety advice

Alcohol
CAUTION
Alcohol should be used with caution while taking Sylate-M 500 Tablet.

Pregnancy
CONSULT YOUR DOCTOR
Sylate-M 500 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding
CONSULT YOUR DOCTOR
Sylate-M 500 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving
CONSULT YOUR DOCTOR
It is not known whether Sylate-M 500 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney
CAUTION
Sylate-M 500 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Sylate-M 500 Tablet is not recommended in patients with severe kidney disease.
Use of Sylate-M 500 Tablet is not recommended in patients with severe kidney disease.

Liver
CAUTION
Sylate-M 500 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Fact Box
Habit Forming
No
Therapeutic Class
BLOOD RELATED
References
- Mefenamic Acid. Atlanta, Georgia: Sciele Pharma Inc.; 2008 [revised Mar. 2007]. [Accessed 02 Apr. 2019] (online) Available from:
- Negrete R, Molina M, Gutierrez-Aceves J. Preoperative administration of ethamsylate: reduces blood loss associated with percutaneous nepholithotomy? A prospective randomized study. J Urol. 2009;181(4S):625. [Accessed 10 Apr. 2019] (online) Available from:
- ScienceDirect. Mefenamic Acid. [Accessed 02 Apr. 2019] (online) Available from:
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User feedback
Twice A Day
50%
Thrice A Day
42%
Once A Day
8%
Bleeding
100%
Excellent
100%
No Side Effect
100%
With food
100%
Not Expensive
67%
Average
33%
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Disclaimer
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Emcure Pharmaceuticals Ltd
Address: 255/2, Hinjawadi, Pune - 411057, India / Godown A, Gat No. 408 and 410, Vill: Urse, Tal: Maval, Pune-410 506, Maharashtra, India.
Address: 255/2, Hinjawadi, Pune - 411057, India / Godown A, Gat No. 408 and 410, Vill: Urse, Tal: Maval, Pune-410 506, Maharashtra, India.
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Sylate-M 500 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Sylate-M 500 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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