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Sputnik V Vaccine helps prevent Coronavirus Disease 2019 (COVID-19) in individuals 18 years of age and older. It is deemed safe and works in a way similar to Covishield. It has an efficacy of over 90% against SARS-CoV-2 infection and is the first foreign vaccine to receive emergency use authorization in India.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 13 Jul 2026 | 01:01 AM (IST)
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General Information

Contains

Human adenovirus vector vaccine (NA)

Marketer

Dr Reddy's Laboratories Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Sputnik V Vaccine image
Sputnik V Vaccine image

Product introduction

Sputnik V Vaccine, the Russian COVID-19 vaccine, is the world’s first Covid-registered vaccine and is already registered in more than 60 countries. The vaccine has been developed by Moscow’s Gamaleya National Center of Epidemiology and Microbiology. In India, along with import, Hyderabad-based Dr. Reddy’s Laboratories (DRL) and a few other pharmaceutical companies will manufacture the vaccine.

Sputnik V Vaccine is administered by a healthcare professional into a muscle (intramuscularly) and should not be self-administered. Sputnik V Vaccine is given in two doses, 21 days apart. However, unlike any other Covid-19 vaccine, both doses of Sputnik V Vaccine are different from one another. This difference in composition of doses helps make the immune response stronger thereby providing extended protection against Covid-19.

Sputnik V Vaccine may cause certain mild and temporary side effects such as injection site pain, tiredness, and fever. If these persist or get worse, let the doctor know. The doctor may help with ways to reduce or prevent these side effects.

To ensure safety, it is important to let the doctor know about your medical conditions. Also, let them know about the medications you are taking.

Uses of Sputnik V Injection

  • Prevention of Coronavirus disease (COVID-19)

Benefits of Sputnik V Injection

Prevention of Coronavirus disease (COVID-19)
Sputnik V Vaccine is used for active immunization against Covid-19 disease in adults. It is given as a two-dose regime. So, make sure to complete the entire dosing schedule. It is considered to have an efficacy of more than 90% and no serious side effects have been reported so far after taking Sputnik V Vaccine. Getting vaccinated is more of social responsibility and plays a major role in contributing our part to save lives.

Additionally, take all the necessary precautions to ensure your safety, such as wearing a face mask, avoiding crowded places, washing your hands or using a hand sanitizer at regular intervals, and maintaining social distancing whenever possible.

Side effects of Sputnik V Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sputnik V
  • Injection site pain
  • Tiredness
  • Fever

How to use Sputnik V Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Sputnik V Injection works

SARS-CoV-2 virus (that causes Covid-19) uses proteins called spike proteins to enter the cells of our body. Sputnik V Vaccine contains two different adenovirus vectors (rAd26 and rAd5), delivered separately in the first and second dose respectively. These contain the gene for making the SARS-CoV-2 spike protein but have been modified so that they cannot cause the disease. Thus once vaccinated, the body produces antibodies against the coronavirus that helps you fight the virus if exposed. This means there is a reduced risk of developing the illness and its consequences. Using different vectors boosts the immune system even more than using the same version twice and may give longer-lasting protection against the virus when exposed to it.

Quick tips

  • Sputnik V Vaccine is a 2-dose vaccination regimen. The second dose is administered 21 days after the first dose.
  • Sputnik V Vaccine is given into the muscle (intramuscularly) of the upper arm.
  • In addition to vaccination, observe other control measures such as social distancing, mask donning, and hand-washing.
  • Sputnik V Vaccine is currently not meant to be administered in children as safety and efficacy are not yet established.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sputnik V Vaccine. Please consult your doctor.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Sputnik V Vaccine is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Sputnik V Vaccine during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Sputnik V Vaccine may cause side effects that could affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Sputnik V Vaccine in patients with kidney disease. Please consult your doctor.
Liver

Liver

CAUTION
Sputnik V Vaccine should be used with caution in patients with liver disease. Dose adjustment may be needed.
All

Frequently asked questions

Sputnik V Vaccine is one of the three vaccines in the world with reported efficacy of over 90%. Furthermore, the clinical trial data published in The Lancet suggests that no serious adverse events were detected. Most adverse effects were mild, with flu-like symptoms, injection site reactions, headache, and fatigue as the most common side effects.
Sputnik V Vaccine has not been studied for safety and effectiveness in the children/pediatric population so far. As per the current guidelines, only people aged 18 years or older are advised to receive this vaccine. Therefore, it is advised not to give any COVID-19 vaccine to children till we have enough data available.
Yes. It is extremely important to get both the doses of Sputnik V Vaccine. This is because Sputnik V Vaccine contains two different virus vectors in each dose and this is what makes it unique. Both the vectors are weakened human adenovirus, namely rAd26 and rAd5, and they cause common cold symptoms such as cold, fever, cough, watery eyes, sneezing, etc, in humans. These are already known viruses, which are easy to study and have been known for a longer time to our health experts. Moreover, it was seen in the conducted trials that this kind of dosing produced better and longer-lasting immunity in people who received both the doses, 21 days apart. So, for best results, you are advised to take both the doses of Sputnik V Vaccine.
The most common side effects of Sputnik V Vaccine are pain at the injection site, generalized tiredness, and fever. However, these are mild and usually resolve with time. If they bother you or do not go away, please consult your doctor. Your doctor will prescribe some medicines or may suggest ways to cope up with these side effects.
As per Russian guidelines, Sputnik V Vaccine can be stored at a temperature of +2 to +8 degrees Celsius, which allows for easy distribution worldwide.
Sputnik V Vaccine is one of the three vaccines globally, having an efficacy of above 90%, the other two being Pfizer-BioNTech and Moderna. The actual efficacy of the vaccine was clocked at 91.6% by the analysis of data received from 19,800+ volunteers who were administered with both doses.
So far, 14 vaccines have been approved in at least 1 country. The other leading vaccines, except Sputnik V Vaccine, that are being used worldwide are Pfizer-BioNTech, Oxford/Astrazeneca, Moderna, Janssen (Johnson and Johnson), Covaxin, and Covishield. Janssen, AstraZeneca, Covishield, and Sputnik are all based on non-replicating viral vector technology. Moderna and Pfizer-BioNTech are RNA-based while Covaxin uses an inactivated protein subunit. Irrespective of the technology being used, all the vaccines aim at preventing Covid-19 and scientists are still studying as well as developing more vaccines to fight against the global pandemic. While most of the vaccines are given in two doses, Janssen is a single-shot vaccine.
Yes. People who have already been infected with COVID-19 should still get vaccinated unless told otherwise by their healthcare provider. Even if you’ve had a previous infection, the vaccine acts as a booster that strengthens the immune response. There have also been some cases of people getting re-infected with COVID-19, which makes getting vaccinated even more important.
Yes. All vaccines are expected to provide a reasonable amount of protection against the newer strains/mutated versions of the COVID-19 virus also. The body responds to vaccination by making more than one type of antibodies, that effectively destroy the virus. Based on the currently available data, the mutations as reported, are unlikely to make the vaccine ineffective and protect an individual against COVID-19 effectively.
Emergency Use Authorization (EUA) or permission for restricted use is a declaration issued by Indian regulators in alignment with global guidelines, to use certain vaccines, medicines, or devices to diagnose, treat or prevent a serious medical condition (such as COVID-19 in the current scenario) in case there is an outbreak of such an illness that poses threat to public health. Regulatory authorities may not approve the use of any such medical measures but may still allow it to be used against the illness weighing the benefits against the risks involved. However, there are continuous lab assessments and clinical trials to check on the safety, effectiveness, and quality of the vaccines.
Coronavirus disease 2019, better known as COVID-19, is an illness of the lungs caused by a virus called SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2), which is seen to infect humans for the very first time. COVID-19 is a highly infectious viral disease that spreads from one person to another at a very fast pace. Persons suffering from COVID-19 are likely to have breathing difficulties, fever, and cough as the major symptoms.

Fact Box

Chemical Class

Viral vector- based vaccine

Habit Forming

No

Therapeutic Class

VACCINES

References

  1. Sputnik V: The first registered vaccine against COVID-19 [General Information]. [Accessed 20 May 2021] (online) Available from:
  2. Baraniuk C. Covid-19: What do we know about Sputnik V and other Russian vaccines? BMJ. 2021;372:n743. [Accessed 20 May 2021] (online) Available from:
  3. Jones I, Roy P. Sputnik V COVID-19 vaccine candidate appears safe and effective. Lancet. 2021;397(10275):642-643. [Accessed 20 May 2021] (online) Available from:
  4. World Health Organization. Coronavirus disease (COVID-19): Vaccines. [Accessed 20 May 2021] (online) Available from:
  5. Barcelona Institute for Global Health. FAQs on COVID-19 Vaccines. [Accessed 20 May 2021] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Dr Reddy's Laboratories Ltd
Address: Dr. Reddy's Laboratories Ltd., Village Malpur, P.O.Bhud, Baddi, Dist. Solan, H.P.

Vendor Details

Country of origin: Russia

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