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Speridon Plus Tablet MD

Risperidone (3mg)+ Trihexyphenidyl (2mg)

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Speridon Plus Tablet MD is a combination medicine used in the treatment of schizophrenia. It works by modulating the action of certain chemical messengers in the brain that affect thoughts.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 22 Sep 2025 | 01:12 AM (IST)

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General Information

Contains

Risperidone (3mg)+ Trihexyphenidyl (2mg)

Marketer

Molekule India Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Speridon Plus Tablet MD is taken with or without food, preferably at night. However, it is advised to take it at the same time each day, as this helps maintain a consistent level of medicine in the body. Take this in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. It is important not to stop this medicine suddenly without talking to the doctor, as it may worsen your symptoms.

Some common side effects of this medicine include nausea, constipation, upper respiratory tract infection, urinary tract infection, tremor, blurred vision, and dryness in the mouth. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. It also causes dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may increase your weight, blood sugar, and cholesterol, but modifying your lifestyle by having a healthy diet and exercising regularly can reduce these side effects.

Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses of Speridon Plus Tablet MD

Treatment of Schizophrenia

Benefits of Speridon Plus Tablet MD

Treatment of Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings, and behavior become abnormal. Speridon Plus Tablet MD helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts and behavior and enhances the quality of life. Do not stop taking it unless advised by the doctor. It can take several weeks for your symptoms to improve, so keep using the medicine even if you do not think it is working.

Side effects of Speridon Plus Tablet MD

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Speridon Plus

Nausea
Constipation
Dryness in mouth
Weight gain
Sleepiness
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Increased prolactin level in blood
Nervousness
Upper respiratory tract infection
Urinary tract infection
Tremors
Blurred vision
Headache
Drooling
Nasal congestion (stuffy nose)

How to use Speridon Plus Tablet MD

Take this medicine in the dose and duration as advised by your doctor. Do not handle the tablets with wet hands. Put it in your mouth but do not swallow it. Speridon Plus Tablet MD may be taken with or without food, but it is better to take it at a fixed time.

How Speridon Plus Tablet MD works

Speridon Plus Tablet MD is a combination of two medicines: Risperidone and Trihexyphenidyl. Risperidone is an atypical antipsychotic that works by balancing the levels of chemical messengers (dopamine and serotonin) to improve mood, thoughts, and behavior. Trihexyphenidyl is an anticholinergic that works on the nervous system and corrects some of the chemical imbalances that cause Parkinson's disease and certain side effects occurring during antipsychotic treatment.

All substitutes for Speridon Plus Tablet MD

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Use caution while driving or doing anything that requires concentration, as Speridon Plus Tablet MD can cause dizziness and sleepiness.
Avoid consuming alcohol while taking this medication, as it may lower its efficacy.
It can cause dry mouth. Maintain good oral hygiene, drink water, chew sugarless gum, or suck on hard candy for the dry mouth.
It may cause an increase in weight, blood sugar, cholesterol, and triglycerides (fat). Eat healthy, exercise, and monitor your levels regularly.
Inform your doctor if you have glaucoma or trouble passing urine.
Do not stop taking Speridon Plus Tablet MD without talking to your doctor first, as it may cause a worsening of symptoms.

Safety advice

Alcohol

UNSAFE

Speridon Plus Tablet MD may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Speridon Plus Tablet MD may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Speridon Plus Tablet MD is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Speridon Plus Tablet MD may cause side effects which could affect your ability to drive.
Speridon Plus Tablet MD can cause blurring of vision, dizziness, mild nausea, and mental confusion in some cases. This may affect your ability to drive.

Kidney

CAUTION

Speridon Plus Tablet MD should be used with caution in patients with kidney disease. Dose adjustment of Speridon Plus Tablet MD may be needed. Please consult your doctor.

Liver

CAUTION

Speridon Plus Tablet MD should be used with caution in patients with liver disease. Dose adjustment of Speridon Plus Tablet MD may be needed. Please consult your doctor.

Frequently asked questions

What is Speridon Plus Tablet MD used for?

Speridon Plus Tablet MD is used to manage symptoms of schizophrenia and other psychiatric conditions. It also helps reduce movement-related side effects caused by antipsychotic medications. Speridon Plus Tablet MD combines two medicines: risperidone, which treats mood and behavior symptoms, and trihexyphenidyl, which helps control movement problems like stiffness or tremors.

How long will I need to take Speridon Plus Tablet MD?

The duration of treatment with Speridon Plus Tablet MD depends on your condition, how well you are responding, and your doctor’s ongoing evaluation. Keep taking it even if you start to feel better, and stop only when your doctor tells you so.

Are there any lifestyle tips while taking Speridon Plus Tablet MD?

Yes. To support your treatment with Speridon Plus Tablet MD, try to stick to a regular sleep schedule, eat a balanced diet, stay hydrated, do light exercise, manage stress, avoid disruptions to your routine, and attend regular doctor visits.

Do I need to make any dietary changes while on Speridon Plus Tablet MD?

Yes. Avoid taking Speridon Plus Tablet MD with acidic foods or drinks like citrus fruits or juices, as they may reduce its effectiveness. Also, do not consume alcohol while on Speridon Plus Tablet MD, as it can lower the medicine’s effect and increase side effects.

When should I avoid taking Speridon Plus Tablet MD?

Avoid taking Speridon Plus Tablet MD if you are allergic to any of its ingredients, have glaucoma, an enlarged prostate, problems with gut movement (such as delayed stomach emptying), or if you are an elderly person with dementia, as it may increase the risk of stroke or death.

What are the serious side effects of Speridon Plus Tablet MD?

The serious side effects of Speridon Plus Tablet MD are high fever, muscle stiffness, or confusion (possible signs of neuroleptic malignant syndrome), uncontrolled movements (tardive dyskinesia), severe dizziness/fainting (due to low blood pressure), increased thirst and frequent urination (signs of high blood sugar), painful, long-lasting erection (priapism), etc. If you notice any of these or other unusual symptoms, contact your doctor immediately.

Fact Box

Habit Forming

Therapeutic Class

NEURO CNS

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Molekule India Pvt Ltd
Address: CRIMPAGE CORPORATION, 3RD FLOOR, PLOT NO. 57, STREET NO. 17, MIDC, MAROL, ANDHERI (EAST), MUMBAI MH 400093 IN , - , .

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Speridon Plus Tablet MD. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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