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Spasril Tablet

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 23 Jan 2026 | 10:15 AM (IST)
Spasril Tablet is used to treat irritable bowel syndrome (symptoms include abdominal pain, cramping, bloating, and diarrhea or constipation). It prevents the sudden spasm of muscles to relieve stomach pain and cramps. It also promotes easy passage of gas to reduce stomach discomfort.
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The content is shown in English
Spasril Tablet image
Spasril Tablet image

Product introduction

Spasril Tablet is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are nausea, constipation, memory impairment, blurred vision, dryness in the mouth, difficulty in urination, and coordination impairment. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.
Lifestyle modifications like having a fiber-rich diet, avoiding foods that trigger your symptoms, increasing fluid intake, and regular exercise can help you to get better results. Before taking it, you should tell your doctor if you have any kidney or liver diseases. You should also tell your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Benefits of Spasril Tablet

Treatment of Irritable bowel syndrome
Irritable bowel syndrome is a chronic (long-term) inflammatory disease of the large intestine (colon) that usually needs long term management. This can lead to bleeding, frequent diarrhea, bloating, flatulence, cramps and stomach pain. Spasril Tablet relaxes the muscles in your stomach and gut(intestine) and relieves these symptoms effectively. Usually, it is used along with other medicines for the management of your condition.
Continue taking it for as long as the doctor may advise you to. You need to take this medicine regularly to get the most out of it. Take a fiber-rich diet, avoid oily or spicy food and drink plenty of fluids while taking it to make sure you stay hydrated.

Side effects of Spasril Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Spasril
  • Sleepiness
  • Nausea
  • Constipation
  • Memory impairment
  • Dizziness
  • Blurred vision
  • Dryness in mouth
  • Difficulty in urination
  • Impaired coordination
  • Depression

How to use Spasril Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Spasril Tablet is to be taken on an empty stomach.

How Spasril Tablet works

Spasril Tablet is a combination of two medicines: Chlordiazepoxide and Clidinium. Chlordiazepoxide is a benzodiazepine. It works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain. Clidinium works by relaxing the muscles in your stomach and gut (intestine). It stops sudden muscle contractions (spasms) which in turn relieves cramps, pain, bloating, and discomfort.

Quick tips

  • Spasril Tablet is prescribed to give relief from the symptoms of irritable bowel syndrome.
  • If you are due to have an operation or any dental treatment, please tell the doctor carrying out the treatment that you are taking Spasril Tablet. This is because it increases the effects of some anesthetics.
  • Inform your doctor if you have an enlarged prostate gland, glaucoma, or trouble passing urine.
  • Inform your doctor if you are pregnant or breastfeeding.
  • If you are 65 or older, use Spasril Tablet with care. You could have more side effects.
  • Spasril Tablet is prescribed to give relief from the symptoms of irritable bowel syndrome.
  • If you are due to have an operation or any dental treatment, please tell the doctor carrying out the treatment that you are taking Spasril Tablet. This is because it increases the effects of some anesthetics.
  • Inform your doctor if you have an enlarged prostate gland, glaucoma, or trouble passing urine.
  • Inform your doctor if you are pregnant or breastfeeding.
  • If you are 65 or older, use Spasril Tablet with care. You could have more side effects.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Spasril Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Spasril Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Spasril Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Spasril Tablet may cause side effects that could affect your ability to drive.
As Spasril Tablet may make you feel drowsy or affect your concentration and this may affect your ability to drive.
Kidney

Kidney

CAUTION
Spasril Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Spasril Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Yes, Spasril Tablet may cause physical dependence as it contains Chlordiazepoxide as one of the ingredients. Physical dependence is defined as the occurrence of a withdrawal reaction following sudden stoppage of the drug or a decrease in dose. Consult your doctor before taking this medicine or if you need to make any change in the dose.
The use of Spasril Tablet is not recommended to patients with known allergy to any of the components or excipients of Spasril Tablet. Its use is also not advisable in patients of glaucoma, benign prostate enlargement and bladder neck obstruction.
Spasril Tablet should not be taken along with opioids-like substances as it contains chlordiazepoxide. Use of opioids along with chlordiazepoxide may cause excessive sedation (state of calm or sleep), respiratory depression and eventually coma or death. Inform your doctor about all the medicines that you are taking if you are advised to take Spasril Tablet.
Both Chlordiazepoxide and Clidinium show different symptoms of overdose. Chlordiazepoxide can cause sleepiness, reflexes, confusion and coma. Clidinium can cause excessive dryness of mouth, blurred vision, urinary hesitancy and constipation. Inform the doctor in case you take a higher dose and any of these symptoms appear.
Yes, Spasril Tablet may make you feel drowsy or sleepy. Do not drive, operate any machines, work at heights, or participate in potentially dangerous activities at the start of your treatment. Inform your doctor if you experience such episodes while you are taking this medicine.
Yes, the use of Spasril Tablet can cause constipation. Eat high-fiber foods like vegetables, fruits and cereals, and drink plenty of water. Exercise regularly by engaging in activities like swimming, jogging or going for a walk. Consult a doctor if constipation persists for a long duration.
No, avoid drinking alcohol while you are taking Spasril Tablet. Drinking alcohol can increase the risk of side effects like drowsiness or sleepiness.
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

Yes

Therapeutic Class

GASTRO INTESTINAL

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User feedback

Twice A Day
50%
Once A Day
43%
Thrice A Day
7%
Irritable bowel syndrome
100%
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135 || Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205

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Country of origin: India
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