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Sothrex Plus Syrup is used to treat cough. It thins the mucus in the nose, making it easier to cough out. This medicine narrows the blood vessels in the nose to relieve congestion or stuffiness. It also relieves allergy symptoms like watery eyes, sneezing, runny nose, and throat irritation.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 24 Sep 2025 | 02:34 PM (IST)
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General Information

Contains

Guaifenesin (50mg/5ml)+ Ambroxol (15mg/5ml)+ Chlorpheniramine Maleate (2mg/5ml)+ Phenylephrine (5mg/5ml)+ Menthol (1mg/5ml)

Marketer

Psychotropics India Ltd

Storage

Store below 25°C
The content is shown in English
Sothrex Plus Syrup image
Sothrex Plus Syrup image
Sothrex Plus Syrup image

Product introduction

Sothrex Plus Syrup is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are nausea, diarrhea, vomiting, stomach discomfort, headache, rash, itching, loss of appetite, and insomnia. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine can also cause sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can make sleepiness worse.

Never support self-medication or recommend your medicine to another person. It is beneficial to have plenty of fluids while taking this medication. Before you start taking this medicine you should tell your doctor if you are pregnant or planning a pregnancy.

Uses of Sothrex Plus Syrup

Benefits of Sothrex Plus Syrup

Cough
Sothrex Plus Syrup gives relief from cough by loosening thick mucus and making it easier to cough it out. It also makes it easier for air to move in and out of your airways. This reduces the frequency of coughing and makes you feel better. Sothrex Plus Syrup also relieves allergy symptoms like watery eyes, sneezing, runny nose or throat irritation. Along with medications, drink enough lukewarm water and gargle with warm salt water to ease the symptoms.

Side effects of Sothrex Plus Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sothrex Plus
  • Nausea
  • Diarrhea
  • Vomiting
  • Stomach discomfort
  • Dizziness
  • Headache
  • Rash
  • Itching
  • Hives
  • Allergic reaction
  • Sleepiness
  • Loss of appetite
  • Insomnia (difficulty in sleeping)

How to use Sothrex Plus Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Sothrex Plus Syrup may be taken with or without food, but it is better to take it at a fixed time.

How Sothrex Plus Syrup works

Sothrex Plus Syrup is a combination of five medicines: Guaifenesin, Ambroxol, Chlorpheniramine Maleate, Phenylephrine and Menthol which relieve cough.

Quick tips

  • Sothrex Plus Syrup is prescribed to get relief from cough.
  • Drink warm water to help loosen the congestion and lubricate your throat while you are taking this medication.
  • Take exactly as directed by your doctor or on the label. Do not increase the dosage or take for longer than is recommended.
  • In general, most coughs do not last more than 2-3 weeks. If your cough does last longer than this then it's better to see your doctor.
  • Inform your doctor if you have a history of stomach ulcers or asthma.

Safety advice

Alcohol

Alcohol

CAUTION
Caution is advised when consuming alcohol with Sothrex Plus Syrup. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Sothrex Plus Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Sothrex Plus Syrup during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Sothrex Plus Syrup may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

SAFE IF PRESCRIBED
Sothrex Plus Syrup is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Sothrex Plus Syrup may not be needed in these patients. Please consult your doctor.
Liver

Liver

SAFE IF PRESCRIBED
Sothrex Plus Syrup is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Sothrex Plus Syrup may not be needed in these patients. Please consult your doctor.

Frequently asked questions

Sothrex Plus Syrup is used to treat cough. It thins the mucus in the nose, making it easier to cough out. This medicine narrows the blood vessels in the nose to relieve congestion or stuffiness. It also relieves allergy symptoms like watery eyes, sneezing, a runny nose, and throat irritation.
Individuals should not take Sothrex Plus Syrup if they are allergic to any ingredient present in it, have high blood pressure, heart disease, glaucoma, urinary retention, or are taking MAO inhibitors or medications.
Although they are rare, serious side effects of Sothrex Plus Syrup may include high blood pressure spikes or severe dizziness. Seek medical help if these occur.
Sothrex Plus Syrup is typically recommended for adults and children over twelve years. Use in younger children only under medical guidance.
Yes, due to chlorpheniramine present in Sothrex Plus Syrup, this medicine may cause sedation. You should avoid driving or operating machinery until you know how it affects you.

Fact Box

Habit Forming

No

Therapeutic Class

RESPIRATORY

References

  1. Chlorpheniramine Maleate + Phenylephrine HCL. Lumberton, New Jersey: AAA Pharmaceutical, Inc. [Accessed 17 Apr. 2019] (online) Available from:
  2. European Medicine Agency. Revised assessment report: Ambroxol; 2001. [Accessed 17 Apr. 2019] (online) Available from:
  3. ScienceDirect. Menthol. [Accessed 17 Apr. 2019] (online) Available from:
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User feedback

Cough
91%
Cough with mucus
9%
Poor
67%
Excellent
22%
Average
11%
No Side Effect
100%
With food
67%
Empty stomach
33%
Average
67%
Expensive
33%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Psychotropics India Ltd
Address: Plot No -17, Sector – 20A, Faridabad, Haryana – 121001, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Sothrex Plus Syrup. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?
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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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