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Last updated
20 May 2025 | 04:16 PM (IST)

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Sompraz D 40 Capsule SR


Product introduction

Sompraz D 40 Capsule SR is a prescription medicine used to treat gastroesophageal reflux disease (acid reflux). It helps relieve symptoms such as heartburn, stomach pain, or irritation. It also neutralizes the acid in the stomach and promotes easy gas passage to reduce stomach discomfort.

Sompraz D 40 Capsule SR is best taken on an empty stomach. Take it in the dose and duration advised by the doctor. Continue taking this medicine for as long as your doctor recommends. If you stop treatment too early, your symptoms may come back, and your condition may worsen. Let your doctor know about all other medications you are taking, as some may affect, or be affected by, this medicine.


The most common side effects of Sompraz D 40 Capsule SR include diarrhea, flatulence, stomach pain, dryness in the mouth, and headache. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any side effects. It may also cause sleepiness and dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.


Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy, or breastfeeding. You should also tell your doctor if you have severe liver disease so that your doctor can prescribe a suitable dose for you. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food, or chocolate can help you get better results.


Benefits of Sompraz D Capsule SR

In Treatment of Gastroesophageal reflux disease (Acid reflux)

Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition in which there is an excess production of acid in the stomach. Sompraz D 40 Capsule SR reduces the amount of acid in your stomach and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.

Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight; and try to find ways to relax. Do not eat within 3-4 hours of going to bed.

Side effects of Sompraz D Capsule SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sompraz D

  • Diarrhea
  • Flatulence
  • Stomach pain
  • Dryness in mouth
  • Headache
  • Nausea

How to use Sompraz D Capsule SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sompraz D 40 Capsule SR is to be taken empty stomach.

How Sompraz D Capsule SR works

Sompraz D 40 Capsule SR is a combination of two medicines: Domperidone and Esomeprazole. Domperidone is a prokinetic that works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Esomeprazole is a proton pump inhibitor (PPI) that works by reducing the amount of acid in the stomach, which helps in the relief of acid-related indigestion and heartburn.

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Sompraz D 40 Capsule SR. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Sompraz D 40 Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
UNSAFE
Sompraz D 40 Capsule SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Sompraz D 40 Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Sompraz D 40 Capsule SR should be used with caution in patients with severe kidney disease. Dose adjustment of Sompraz D 40 Capsule SR may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Sompraz D 40 Capsule SR is safe to use in patients with liver disease. No dose adjustment of Sompraz D 40 Capsule SR is recommended.

What if you forget to take Sompraz D Capsule SR?

If you miss a dose of Sompraz D 40 Capsule SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Sompraz D 40 Capsule SR
₹17.13/Capsule SR
Es-omepraz -DSR Capsule
Alkem Laboratories Ltd
₹8.6/capsule sr
50% cheaper
Espra DSR Capsule
Zydus Cadila
₹13/capsule sr
24% cheaper
Nexopil -DSR Capsule
Psychotropics India Ltd
₹8.7/capsule sr
49% cheaper
Nexpro RD 40 Capsule SR
Torrent Pharmaceuticals Ltd
₹19.1/capsule sr
12% costlier
₹20/capsule sr
17% costlier

Quick tips

  • Take Sompraz D 40 Capsule SR on an empty stomach 30 minutes to 1 hour before the meal.
  • It is a well-tolerated medicine and provides relief for a long time.
  • Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
  • Long-term use can cause weak bones and a deficiency of minerals such as magnesium.
  • Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.

Fact Box

Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL

Patient concerns

Gastric nausea vomiting reflux
Dr. Pushkar Mani
Physician
sompraz D 40 mg twice daily 1 hour before meal for 10 days
Many a times I feel acid reflux in the evening. Need help with diet to avoid that
Dr. Sfurti Mann
Internal Medicine
Avoid oily spicy food , eat small frequent meals can take tab sompraz IT before breakfast.

User feedback


FAQs

Is it safe to use Sompraz D 40 Capsule SR?

Yes, Sompraz D 40 Capsule SR is safe for most of the patients. However, in some patients, it may cause common side effects like diarrhea, stomach pain, flatulence, dryness in the mouth, dizziness, headache, and other uncommon and rare side effects. Inform your doctor if you experience any persistent problems while taking this medicine.

What is the best time to take Sompraz D 40 Capsule SR?

It is best to take Sompraz D 40 Capsule SR before the first meal of the day or on an empty stomach.

What are the contraindications associated with the use of Sompraz D 40 Capsule SR?

The use of Sompraz D 40 Capsule SR is considered to be harmful for patients with a known hypersensitivity to esomeprazole and domperidone or any other inactive ingredients of the medicine. Caution is advised in patients with underlying kidney or liver disease.

Can the use of Sompraz D 40 Capsule SR cause dry mouth?

Yes, the use of Sompraz D 40 Capsule SR can cause dry mouth. Dryness of the mouth occurs due to domperidone. If you experience dry mouth, drink plenty of water. Take regular sips of water during the day and keep some water on your bedside at night. If you have a dry mouth, try to use alcohol-free mouthwash, as its use can increase the risk of tooth decay.

Can the use of Sompraz D 40 Capsule SR cause diarrhea?

Yes, the use of Sompraz D 40 Capsule SR can cause diarrhea. In case of diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists and if you notice signs of dehydration, like less frequent urination and dark-colored and strong-smelling urine. Avoid taking fatty or fried foods with this medication. Also, do not take any medicines without consulting the doctor.

What are the storage conditions for Sompraz D 40 Capsule SR?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Esomeprazole [EMC Label]. Luton, UK: AstraZeneca UK Ltd.; 2018. [Accessed 12 Apr. 2019] (online) Available from: External Link
  2. International Breastfeeding Center. Domperidone. [Accessed 12 Apr. 2019] (online) Available from: External Link
  3. Esomeprazole Magnesium and Domperidone Sustained Release [Patient Information Leaflet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Pvt. Ltd.; 2022. [Accessed 28th Sept. 2023] (online) Available from: External Link
  4. Esomeprazole and Domperidone [Product Information]. Mumbai, Maharashtra: Blue Cross Laboratories Pvt Ltd.; 2023. [Accessed 13 Mar. 2025] (online) Available from: External Link

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Country of origin: India
Expires on or after: December, 2025

A licensed vendor partner from your nearest location will deliver Sompraz D 40 Capsule SR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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