Silofirst D 8mg/0.5mg Tablet is a combination of two medicines that work in different ways to treat men with an enlarged prostate gland. It helps to relieve symptoms such as difficulty urinating or needing to go to the toilet more often. It is not used to prevent prostate cancer.

Silofirst D 8mg/0.5mg Tablet should be taken at the same time each day. Take it as a whole, do not break, chew, or crush them. Your doctor will prescribe the dose most suitable for you. To gain the most benefit and treat your symptoms effectively you should not miss doses, even if you feel well. It may take up to 4 weeks to notice an improvement in symptoms but keep taking them regularly. Tell your doctor if your symptoms do not improve after 4 weeks or if they get worse.

The most common side effects of this medicine include decreased libido, inability to get an erection (impotence), breast tenderness, and enlargement of your breasts. If these effects worry you or do not go away, call your doctor for advice. You may also feel dizzy or drowsy. These risks are higher when you first start taking this drug. Remember, your doctor has given you this medicine because the benefits are greater than the risks of the side effects.

This medicine should not be taken by women or children. Before taking it, tell your doctor if you have low blood pressure or liver or kidney disease. This medicine may not be suitable. It can also affect, or be affected by, other drugs so let your doctor know all other medicines you are taking. You may be advised to wear a condom during sex and to have your blood pressure checked frequently. Talk to your healthcare team if you drink alcohol.

Uses of Silofirst D Tablet

Treatment of Benign prostatic hyperplasia

Benefits of Silofirst D Tablet

In Treatment of Benign prostatic hyperplasia

When your prostate gland becomes enlarged it can cause urinary problems such as difficulty passing urine and a need to go to the toilet frequently or urgently. It can also cause urine flow to be slower. If not treated, there is a risk that your urine flow will be completely blocked. Silofirst D 8mg/0.5mg Tablet is a combination of two medicines that reduces the size of your prostate by blocking the production of a hormone which causes it to grow. Additionally, it relaxes the muscles in the bladder and prostate. Together they can rapidly relieve the symptoms and make it easier for you to urinate. However, it may take up to 6 months to notice the full benefits. Take this medicine exactly as prescribed for maximum benefits.

Side effects of Silofirst D Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Silofirst D

Ejaculation disorder
Impotence
Decreased libido
Breast enlargement in male
Breast tenderness in male
Headache
Dizziness
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Nausea
Abdominal pain
Diarrhea
Nasopharyngitis (inflammation of the throat and nasal passages)

How to use Silofirst D Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Silofirst D 8mg/0.5mg Tablet is to be taken with food.

How Silofirst D Tablet works

Silofirst D 8mg/0.5mg Tablet is a combination of two medicines: Silodosin and Dutasteride, which relieves the symptoms of benign prostatic hyperplasia. Silodosin is an alpha-blocker. It works by relaxing the muscle around the bladder exit and prostate gland so as to allow easy passage of urine. Dutasteride is a 5-alpha-reductase inhibitor which helps in shrinking the prostate gland by decreasing the level of the hormone which helps the prostate gland grow.

Safety advice

Alcohol

UNSAFE

Silofirst D 8mg/0.5mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Silofirst D 8mg/0.5mg Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Silofirst D 8mg/0.5mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Silofirst D 8mg/0.5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Silofirst D 8mg/0.5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Silofirst D 8mg/0.5mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Silofirst D 8mg/0.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Silofirst D 8mg/0.5mg Tablet may be needed. Please consult your doctor.
Use of Silofirst D 8mg/0.5mg Tablet is not recommended in patients with severe liver disease.

What if you forget to take Silofirst D Tablet?

If you miss a dose of Silofirst D 8mg/0.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Silofirst D 8mg/0.5mg Tablet

₹44.3/Tablet

Alphacept-D 8 Tablet

Lupin Ltd

₹45/tablet

2% costlier

Maxvoid Plus 8 Tablet

Alkem Laboratories Ltd

₹47.2/tablet

7% costlier

Silotrif-D 8 Tablet

MSN Laboratories

₹45.3/tablet

2% costlier

Silosam D 8 Tablet

Samarth Life Sciences Pvt Ltd

₹39.47/tablet

11% cheaper

AMPS-SD Tablet

AMPS Biotech Pvt Ltd

₹43.6/tablet

2% cheaper

View all substitutes

Quick tips

You have been prescribed Silofirst D 8mg/0.5mg Tablet to relieve the symptoms of benign prostatic hyperplasia (BPH).
Take it approximately 30 minutes after the same meal each day.
Silofirst D 8mg/0.5mg Tablet may cause dizziness or blurring of vision. Do not drive or do anything requiring concentration until you know how it affects you.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
If you are scheduled to undergo an eye surgery due to cataract or glaucoma, inform your eye doctor about the usage of Silofirst D 8mg/0.5mg Tablet.
It may cause difficulty achieving or maintaining an erection (impotence), decreased sex drive, and ejaculation disorders such as decreased amount of semen produced or decreased sperm count.
Do not donate blood for 6 months after taking the last dose of Silofirst D 8mg/0.5mg Tablet.

Fact Box

Habit Forming

Therapeutic Class

UROLOGY

Patient concerns

What is hyperplasia nd wht a treatment

Dr. Banashree Majumdar

Dermatology

Mr. PATIENT is not a medical condition, it's just a histological term mentioned in pathology reports

Sir please advice PSA very rise

Dr. Vijay Sharnangat

Medical Oncology and Hematology

It's benign enlargement of prostate

FAQs

Is Silofirst D 8mg/0.5mg Tablet effective?

Silofirst D 8mg/0.5mg Tablet is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Silofirst D 8mg/0.5mg Tablet too early, the symptoms may return or worsen.

What is benign prostate hyperplasia (BPH)?

Benign prostatic hyperplasia (BPH) is also known as prostate gland enlargement. It is a common condition in older men. BPH may cause symptoms like frequent or urgent need to urinate, increased frequency of urination at night (nocturia) and inability to completely empty the bladder.

Can the use of Silofirst D 8mg/0.5mg Tablet cause dizziness?

Yes, the use of Silofirst D 8mg/0.5mg Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. These symptoms could be due to the presence of silodosin in the medicine. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.

Are there any specific contraindications associated with the use of Silofirst D 8mg/0.5mg Tablet?

The use of Silofirst D 8mg/0.5mg Tablet is considered to be harmful in patients who are allergic to any active or inactive ingredients of the medicine. Caution is advised in patients with underlying kidney or liver disease. If not sure, consult your doctor.

What are the instructions for storage and disposal of Silofirst D 8mg/0.5mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Is Silofirst D 8mg/0.5mg Tablet safe?

Silofirst D 8mg/0.5mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

What is the best time to take Silofirst D 8mg/0.5mg Tablet?

It is best to take Silofirst D 8mg/0.5mg Tablet after meals. The capsules should be swallowed whole; do not chew or split. Follow the doctor’s advice properly and do not miss the dose.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

CiplaMed. Silodosin + Dutasteride. [Accessed 25 Apr. 2019] (online) Available from:
Silodosin. Corona, California: Watson Laboratories, Inc.; 2008 [revised Jan. 2013]. [Accessed 04 Apr. 2019] (online) Available from:
Dutasteride. Research Triangle Park, North Carolina: GlaxoSmithKline; 2001 [revised Jun. 2008]. [Accessed 04 Apr. 2019] (online) Available from:
La Renon. Silodosin and Dutasteride [Product Information]. [Accessed 28th Sept. 2023] (online) Available from:
[Accessed 28th Sept. 2023] (online) Available from:

Marketer details

Name: Johnlee Pharmaceuticals Pvt Ltd

Address: 42/44, Babu Genu Road, Shop No. 06, 2nd Floor, Om Shanti Co-op Housing Society, Kalbadevi Road, Mumbai-400002. (India)

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.