Sifazyme Tablet

Diastase (10mg)+ Pepsin (10mg)

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Sifazyme Tablet is a digestive enzyme supplement used in the treatment of indigestion/dyspepsia. It helps break down complex food molecules into simpler forms and facilitates better absorption of essential nutrients. This action provides relief from indigestion, bloating, and discomfort after having meals.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 19 Jun 2026 | 02:30 PM (IST)

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General Information

Contains

Diastase (10mg)+ Pepsin (10mg)

Marketer

Pride Pharma

The content is shown in English

Product introduction

Sifazyme Tablet may be taken with or without food. However, always take it in the dose and duration prescribed by your doctor. Continue taking the medicine for as long as your doctor prescribes it even if you feel better. If you stop taking the medicine abruptly, the symptoms may return. Your dose may be decreased gradually over a few days if the doctor finds it suitable to stop the treatment.

Some common side effects of this medicine include nausea, constipation, skin rash, and pruritus. These side effects mostly occur at the initial stage of the treatment and usually disappear within a few days with continued treatment. If any of these symptoms get worse or bother you, consult with the doctor.

Do not take Sifazyme Tablet if you have a known history of allergic reactions to any of the ingredients of this medicine. Let your doctor know if you are taking, have recently taken, or might take any other medicines. To ensure that this medication is safe for you, let the doctor also know if you have any pre-existing medical conditions, are pregnant, are planning to become pregnant, or are breastfeeding.

Uses of Sifazyme Tablet

Treatment of Indigestion

Benefits of Sifazyme Tablet

Treatment of Indigestion
Sifazyme Tablet digests complex carbohydrates and proteins into their simpler constituents and provides relief from various symptoms caused by indigestion.

Side effects of Sifazyme Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sifazyme

Constipation
Skin rash
Itching
Nausea

How to use Sifazyme Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sifazyme Tablet may be taken with or without food.

How Sifazyme Tablet works

Sifazyme Tablet is a combination of two digestive enzymes. Diastase breaks down complex carbohydrates into simple sugars that can be more easily metabolized. On the other hand, pepsin breaks down proteins into smaller peptides and amino acids for their easy absorption in the small intestine.

Quick tips

Inform your doctor if you are allergic to any of the ingredients of this medicine.
Tell your doctor if you are taking, have recently taken, or might take any other medicines.
Do not take this medicine after the expiry date shown on the pack.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Sifazyme Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Sifazyme Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Sifazyme Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Sifazyme Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Sifazyme Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Sifazyme Tablet in patients with liver disease.

Frequently asked questions

What is Sifazyme Tablet used for?

Sifazyme Tablet is used to help improve digestion and provide relief from indigestion, stomach heaviness, bloating, gas, fullness after meals, and digestive discomfort. It may also help when food is not digested properly, leading to symptoms such as burping, abdominal discomfort, or loss of appetite. Some individuals may notice improved digestion and reduced stomach heaviness after regular use.

How does Sifazyme Tablet work?

Sifazyme Tablet contains digestive enzymes that help break down food into simpler forms so that it can be absorbed more easily by the body. Diastase helps digest carbohydrates, while Pepsin helps break down proteins into smaller particles. This may help improve digestion, reduce bloating, and support better absorption of nutrients from food.

Can Sifazyme Tablet help with bloating and gas after meals?

Yes, Sifazyme Tablet may help relieve bloating, fullness, gas, and digestive discomfort that can occur after meals, especially when food digestion is slow or incomplete. Improved digestion may help reduce the feeling of heaviness and abdominal discomfort after eating.

Can Sifazyme Tablet be taken on an empty stomach?

It is generally preferred after meals, as digestive enzymes work on the food present in the stomach and digestive tract. Taking it after eating may help improve digestion and reduce post-meal discomfort more effectively.

How do Diastase and Pepsin help in food absorption?

Diastase breaks down complex carbohydrates into simpler sugars that are easier to digest and absorb. Pepsin helps digest proteins by breaking them into smaller peptides and amino acids. This process helps the body absorb nutrients more efficiently from food.

How long can I use Sifazyme Tablet?

Use Sifazyme Tablet for the duration advised by your doctor. If your symptoms improve, do not stop treatment abruptly without guidance if you have been advised to continue it for a specific period. If indigestion, bloating, or stomach discomfort continue despite regular use, the underlying cause may need further evaluation.

Can people with enzyme allergies take Sifazyme Tablet?

No. If you have a known allergy to diastase, pepsin, or any ingredient in the syrup, avoid using Sifazyme Tablet unless specifically advised by your doctor. Seek medical attention if you develop rash, itching, swelling, or breathing difficulty after taking it.

Can I take Sifazyme Tablet along with medicines for acidity or other stomach problems?

Inform your doctor about all medicines you are taking, including treatments for acidity, indigestion, diabetes, or other digestive conditions. Some medicines may interact with digestive enzyme preparations. This helps ensure safe and effective treatment.

Can Sifazyme Tablet help improve food digestion and appetite?

Yes, by helping break down carbohydrates and proteins more effectively, Sifazyme Tablet may improve digestion and reduce the discomfort that sometimes affects appetite. Some individuals may notice better appetite and less stomach heaviness after meals.

Why do I still feel bloated even after taking Sifazyme Tablet?

Digestive symptoms may have multiple causes, including overeating, fatty meals, food intolerances, stress, or underlying digestive conditions. While Sifazyme Tablet may help improve digestion, symptom relief may vary between individuals. If bloating continues or worsens despite regular use, further evaluation may be needed.

Can Sifazyme Tablet be used daily for digestion problems?

Some individuals may use digestive enzyme preparations regularly when advised by their doctor. However, prolonged self-medication without understanding the cause of digestive symptoms is not recommended. Persistent indigestion, gas, or stomach discomfort may require medical attention by your doctor.

Fact Box

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Pride Pharma
Address: Pride Pharma, No. 24, Shri Ram Complex, No. 94/1, Shri Ram Puram Colony, Dehradun-248001, Uttarakhand, India

Vendor Details

Country of origin: India

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Gastro Intestinal

Enzyme Combinations

Sifazyme Tablet

Sifazyme Tablet

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General Information

Contains

Marketer

Product introduction

Uses of Sifazyme Tablet

Benefits of Sifazyme Tablet

Side effects of Sifazyme Tablet

How to use Sifazyme Tablet

How Sifazyme Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Sifazyme Tablet used for?

How does Sifazyme Tablet work?

Can Sifazyme Tablet help with bloating and gas after meals?

Can Sifazyme Tablet be taken on an empty stomach?

How do Diastase and Pepsin help in food absorption?

How long can I use Sifazyme Tablet?

Can people with enzyme allergies take Sifazyme Tablet?

Can I take Sifazyme Tablet along with medicines for acidity or other stomach problems?

Can Sifazyme Tablet help improve food digestion and appetite?

Why do I still feel bloated even after taking Sifazyme Tablet?

Can Sifazyme Tablet be used daily for digestion problems?

Fact Box

Habit Forming

Therapeutic Class

References

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Have issue with the content

Disclaimer

Marketer details

Vendor Details

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