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SEREnace Injection 1ml

Haloperidol Decanoate (5mg)

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SEREnace Injection 1ml is used in the treatment of schizophrenia. It is also used to treat psychosis, mania, severe behavior problems, and Tourette syndrome (chronic multiple motor and vocal problems and involuntary responses) in adults and children.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 10 Mar 2026 | 11:05 AM (IST)

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5 injections

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General Information

Contains

Haloperidol Decanoate (5mg)

Marketer

RPG Life Sciences Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

SEREnace Injection 1ml works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood. It is given under the supervision of a healthcare professional only. Use it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. Do not stop suddenly without talking to the doctor, as it may worsen your symptoms. The doctor may check heart function and level of electrolytes such as sodium and magnesium before you start treatment with this medicine and regularly thereafter. Take plenty of fluids while taking this medicine as it may also cause dehydration.

Some common side effects of this medicine include injection site reactions (pain, swelling, redness), dryness in the mouth, urinary retention, constipation, and tremor. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It also causes dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. Additionally, this medicine can lead to weight gain, eat a healthy balanced diet, and exercise regularly.

Uses of SEREnace Injection

Schizophrenia

Benefits of SEREnace Injection

Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. SEREnace Injection 1ml helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

Side effects of SEREnace Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of SEREnace

Abnormality of voluntary movements
Constipation
Dryness in mouth
Increased prolactin level in blood
Muscle stiffness
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Sleepiness
Tremors
Urinary retention
Weight gain

How to use SEREnace Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How SEREnace Injection works

SEREnace Injection 1ml is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

All substitutes for SEREnace Injection 1ml

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Use caution while driving or doing anything that requires concentration as SEREnace Injection 1ml may cause dizziness and sleepiness.
Avoid drinking alcohol while taking this medicine as it can cause increased dizziness.
It may affect how your body regulates your temperature. Avoid getting dehydrated and drink plenty of fluids.
Inform your doctor if you experience any abnormal movements or have difficulty controlling movements.
Inform your doctor if you experience symptoms such as high fever, sweating, muscle stiffness, and faster breathing. These may be due to a rare side effect known as the neuroleptic malignant syndrome.
Your doctor may check your heart function and level of electrolytes such as sodium and magnesium before you start treatment with this medicine and regularly thereafter.
Do not stop taking SEREnace Injection 1ml without talking to your doctor first as it may cause worsening of symptoms.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. SEREnace Injection 1ml may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

The safety of SEREnace Injection 1ml during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

SEREnace Injection 1ml should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

SEREnace Injection 1ml may cause side effects that could affect your ability to drive.

Kidney

CAUTION

SEREnace Injection 1ml should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

SEREnace Injection 1ml should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

What is SEREnace Injection 1ml used for?

SEREnace Injection 1ml is a long‑acting antipsychotic injection given into the muscle to treat schizophrenia in people who need ongoing, monthly treatment to help prevent symptom relapses.

Who should not receive SEREnace Injection 1ml?

Individuals should not use SEREnace Injection 1ml if they have Parkinson’s disease, dementia with Lewy bodies, a severe allergy to haloperidol, or severe central nervous system depression/coma. It must not be given into a vein.

What serious heart risks should be watched for during SEREnace Injection 1ml treatment?

While on SEREnace Injection 1ml treatment, cases of sudden death, dangerous heart rhythm changes (QTc prolongation), and a rhythm called torsades de pointes have been reported. Risk is higher with high doses, low potassium or magnesium, existing heart problems, thyroid issues, or when used with other QT‑prolonging medicines.

Can SEREnace Injection 1ml cause long‑term movement problems?

Yes, tardive dyskinesia (uncontrolled, possibly permanent movements) can happen from SEREnace Injection 1ml use, especially with longer use and higher total doses. Doctors aim for the lowest effective dose and regularly reassess the need for ongoing treatment.

Can SEREnace Injection 1ml cause neuroleptic malignant Syndrome (NMS), and what are the signs?

SEREnace Injection 1ml can cause neuroleptic malignant syndrome (NMS), which is a rare, life‑threatening reaction with very high fever, severe muscle stiffness, confusion, unstable heart rate or blood pressure, and possible kidney injury. Treatment requires stopping SEREnace Injection 1ml and urgent hospital care.

What blood or liver problems can occur with SEREnace Injection 1ml use?

Low white blood cells (including severe neutropenia), liver injury (including acute liver failure, hepatitis, jaundice), and blood abnormalities have been reported with SEREnace Injection 1ml use. Doctors may monitor blood counts and liver tests and stop treatment if serious changes occur.

During SEREnace Injection 1ml treatment, what immediate symptoms need emergency care?

During SEREnace Injection 1ml treatment, severe chest pain or fainting, very fast or irregular heartbeat, severe dizziness, uncontrollable muscle movements, very high fever with rigidity, trouble breathing or swelling of face/throat, or severe allergic rash/peeling skin should be treated as emergencies.

Fact Box

Chemical Class

Alkyl- phenylketones

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Typical Antipsychotics

References

User feedback

Patients taking SEREnace Injection 1ml

Once A Day

45%

Once A Month

30%

Once A Week

Thrice A Day

Twice A Day

Twice A Week

What are you using SEREnace Injection for?

Schizophrenia

77%

Others

23%

How much was the improvement?

Average

53%

Excellent

33%

Poor

13%

What were the side-effects while using SEREnace Injection 1ml?

Sleepiness

27%

Orthostatic hypotension (sudden lowering of blood pressure on standing)

27%

Abnormality of voluntary movements

18%

Dryness in mouth

18%

Weight gain

How do you take SEREnace Injection?

With food

100%

Please rate SEREnace Injection 1ml on price

Not Expensive

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: RPG Life Sciences Ltd
Address: 463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver SEREnace Injection 1ml. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

SEREnace Injection 1ml

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of SEREnace Injection

Benefits of SEREnace Injection

Side effects of SEREnace Injection

How to use SEREnace Injection

How SEREnace Injection works

All substitutes for SEREnace Injection 1ml

Trancodol 5mg Injection

Halow Injection

Sydol 5mg Injection

Talendol 5mg Injection

Mindol 5mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is SEREnace Injection 1ml used for?

Who should not receive SEREnace Injection 1ml?

What serious heart risks should be watched for during SEREnace Injection 1ml treatment?

Can SEREnace Injection 1ml cause long‑term movement problems?

Can SEREnace Injection 1ml cause neuroleptic malignant Syndrome (NMS), and what are the signs?

What blood or liver problems can occur with SEREnace Injection 1ml use?

During SEREnace Injection 1ml treatment, what immediate symptoms need emergency care?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking SEREnace Injection 1ml

What are you using SEREnace Injection for?

How much was the improvement?

What were the side-effects while using SEREnace Injection 1ml?

How do you take SEREnace Injection?

Please rate SEREnace Injection 1ml on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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