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Rs.227.51for 1 tube(s) (250 GM cream each)
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Composition FOR SAPHRINE

Sulfadiazine(1%),Chlorhexidine Gluconate(0.2%)

food interaction for SAPHRINE

alcohol interaction for SAPHRINE

pregnancy interaction for SAPHRINE

lactation interaction for SAPHRINE

medicine interaction for SAPHRINE

No interaction found
No interaction found
Saphrine 1%/0.2% cream may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.
No interaction found




Sulfadiazine is used in the treatment of bacterial infections

How it works

Sulfadiazine is an antibiotic. It stops bacteria from producing folic acid, a vitamin required for bacterial replication.

Common side effects

Nausea, Numbness, Depression, Altered sleep, Burning pain, Diarrhoea, Dizziness, Headache, Loss of appetite, Balance disorder (loss of balance), Coordination impaired, Ringing in ear, Stomach pain, Tingling sensation, Vertigo, Vomiting
Chlorhexidine Gluconate(0.2%)


Chlorhexidine Gluconate is used in the treatment of inflammation of gums and bad odor from mouth

How it works

Chlorhexidine gluconate belongs to a class of medication call antiseptic. It acts by killing as well as preventing bacterial growth. It kills bacteria by interacting with its cell surface.

Common side effects

Allergic reaction, Skin redness, Teeth discolouration, Burning sensation of tongue, Altered taste


4 Substitutes
4 Substitutes
Sorted By
    (15 GM cream in tube)
    Laborate Pharmaceuticals India Ltd
    Rs. 1.25/GM of cream
    Rs. 18.75
    pay 37% more per GM of cream
    (10 GM cream in tube)
    Dales Pharmaceuticals Ltd
    Rs. 0.90/GM of cream
    Rs. 9
    save 1% more per GM of cream
  • ARGISEPT 1%/0.2% CREAM
    (10 GM cream in tube)
    Centaur Pharmaceuticals Pvt Ltd
    Rs. 2.37/GM of cream
    Rs. 23.73
    pay 161% more per GM of cream
  • SILVO 1%/0.2% CREAM
    (30 GM cream in tube)
    Lincoln Pharmaceuticals Ltd
    Rs. 0.98/GM of cream
    Rs. 29.42
    pay 8% more per GM of cream

Expert advice FOR SAPHRINE

  • Complete the full course of sulfadiazine treatment to clear the infection and to prevent the development of bacterial resistance.
  • Consult your doctor immediately if you develop any infection as long term use of sulfadiazine is known to cause secondary infection.
  • Avoid exposure to sunlight as sulfadiazine may increase the sensitivity to the sun.
  • Take sulfadiazine with caution if you have diarrhea, sore throat, stomach or intestinal infection; or if you have a history of asthma, glucose-6-phosphate dehydrogenase (G6PD) deficiency or any other blood problems.
  • Take necessary precaution if you have diabetes as sulfadiazine may cause low blood sugar.
  • Do not drive or operate machinery as sulfadiazine may cause dizziness.
  • Do not consume alcohol along with sulfadiazine as it may worsen the side effects.

Frequently asked questions FOR SAPHRINE


Q. Is sulfadiazine an antibiotic?
Sulfadiazine belongs to class of medicines called sulfonamide antibiotic

Q. Does sulfadiazine contain sulfa?
It contains sulfa

Q. Is sulfadiazine the same as sulfasalazine?
No. Sulfadiazine is different from sulfasalazine.

Chlorhexidine Gluconate

Q. How does chlorhexidine gluconate work?
Chlorhexidine gluconate belongs to a class of medication call antiseptic. It acts by killing as well as preventing bacterial growth. It kills bacteria by interacting with its cell surface

Q. Does it burn?
It is not generally known to burn. Please inform the doctor in case of any side effects

Q. Is chlorhexidine gluconate an antibiotic/antifungal/cure acne/cause cancer/good for canker sores?
Chlorhexidine gluconate is not antibiotic/antifungal. It is not used for curing acne and it does not cause cancer. Canker sores (small and shallow ulcers of the mouth) if mild to moderate then can be controlled by using chlorhexidine gluconate mouthwash

Q. Is chlorhexidine gluconate safe?
Chlorhexidine gluconate is safe when taken for an indication and at a dose strictly instructed by your doctor

Q. Is chlorhexidine gluconate an over the counter or prescription only drug?
Chlorhexidine gluconate is an over the counter drug and not a prescription drug

Q. Is chlorhexidine gluconate whiten teeth/contain iodine/stain teeth?
Chlorhexidine gluconate is not used to whiten teeth. It does not contain iodine. It may stain the teeth slightly but this may be removed by brushing with a normal toothpaste

Q. Does chlorhexidine gluconate mouthwash expire?
Chlorhexidine gluconate mouthwash has an expiry date. It should not be used beyond that date.


Content on this page was last updated on 12 January, 2017, by Dr. Varun Gupta (MD Pharmacology)