Ryverna Solution for Infusion is a medicine used to treat sickle cell anemia in patients aged 16 years and older. It stops certain cells in the blood from sticking together and blocking the blood flow. This helps to reduce the number of painful episodes and improves overall quality of life for patients with the condition.
Ryverna Solution for Infusion is administered as an intravenous infusion. Follow the dosing schedule as prescribed by your doctor. Get the injection regularly and for as long as the doctor has prescribed for maximum benefits. Maintain regular appointments and follow any additional recommendations from your doctor to enhance the effectiveness of the treatment.
The most common side effects of Ryverna Solution for Infusion are joint pain, back pain, nausea, fever, and abdominal pain. These side effects are usually mild and temporary. If you experience any severe or persistent side effects, consult your doctor. They may be able to help manage or prevent the side effects.
Do not use Ryverna Solution for Infusion if you have a known history of allergic reactions to any of the components of this medicine. Let your doctor also know about any other medications you are taking to avoid potential interactions. Women who are pregnant or breastfeeding should consult their doctor before starting Ryverna Solution for Infusion.
Ryverna Solution for Infusion is a medicine taken to reduce the number of painful episodes experienced by individuals with sickle cell anemia. When sickled red blood cells block blood flow, it leads to severe pain and potential complications. Ryverna Solution for Infusion works by preventing sickled red blood cells from sticking to blood vessels, which helps to keep blood flowing smoothly and avoid blockages. Reducing the frequency and severity of pain results in fewer hospitalizations and less disruption to daily life, improving overall quality of life for patients.
Side effects of Ryverna Solution for Infusion
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ryverna
Joint pain
Back pain
Nausea
Fever
Abdominal pain
How to use Ryverna Solution for Infusion
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
How Ryverna Solution for Infusion works
Ryverna Solution for Infusion is a monoclonal antibody that works by blocking a molecule called P-selectin, which plays a key role in the sticking of blood cells to blood vessel walls. In sickle cell anemia, this sticking leads to blockages in blood flow, causing painful episodes known as vaso-occlusive crises. Ryverna Solution for Infusion helps maintain smoother blood flow, reducing the frequency of pain crises and improving overall blood circulation in people with sickle cell disease.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Ryverna Solution for Infusion. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Ryverna Solution for Infusion during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Ryverna Solution for Infusion during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Ryverna Solution for Infusion may cause side effects which could affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Ryverna Solution for Infusion in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Ryverna Solution for Infusion in patients with liver disease. Please consult your doctor.
What if you forget to take Ryverna Solution for Infusion?
If you miss a dose of Ryverna Solution for Infusion, consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
Stick to your infusion schedule for maximum benefits. Missing doses can reduce the effectiveness of the treatment.
Drink plenty of water to help your body handle the medication and reduce side effects.
Be alert for symptoms like rash, itching, swelling, or difficulty breathing. Seek immediate medical attention if these occur.
Complement the treatment with a healthy diet and regular exercise to support your overall well-being.
Educate yourself about sickle cell anemia and the benefits of Ryverna Solution for Infusion to stay proactive in managing your health.
Fact Box
Chemical Class
Peptides
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Monoclonal Antibodies (mAbs)
Patient concerns
I'm sickle cell patient now strong pain occurs what i can do ,my MRI report uploaded
Dr. Kamal Rijhwani
Physician
There is sickle cell society in NagpurFind on net and consult
the injection said is Haemaz fort Injection of 5 ml, total 4 nos. injection is injected to sickle cell disease patient, if Hb is 7 gram, what will be the effect to patient?
Dr. Pushkar Mani
Physician
we dont treat sickle cell anaemia online, u need to consult hematologist
I have a stomach problem? When I am eating anything I have to go toilet with in five minute.(in toilet Frist white liquid come.) I am positive(Trait) with sickle cell anemia. Plz help me.
Ryverna Solution for Infusion is used to reduce the frequency of painful episodes in patients with sickle cell anemia.
What is Ryverna Solution for Infusion used for?
Ryverna Solution for Infusion is used to reduce the frequency of painful episodes in patients with sickle cell anemia.
How is Ryverna Solution for Infusion administered?
Ryverna Solution for Infusion is administered as an intravenous infusion, typically once every four weeks.
What should I do if I miss a dose?
If you miss a dose, consult your doctor to reschedule as soon as possible. It is important to stick to the dosing schedule.
Can pregnant or breastfeeding women receive Ryverna Solution for Infusion?
Women who are pregnant or breastfeeding should consult their doctor before starting Ryverna Solution for Infusion.
Can Ryverna Solution for Infusion be used with other sickle cell treatments?
Discuss with your doctor about any other treatments you are on, as Ryverna Solution for Infusion can be part of a comprehensive treatment plan for sickle cell anemia.
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References
Crizanlizumab [Professional Information]. Johannesburg, South Africa: Novartis South Africa (Pty) Ltd.; 2022. [Accessed 08 Augl. 2024] (online) Available from:
Crizanlizumab [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2024. [Accessed 08 Augl. 2024] (online) Available from:
Press Release: New Novartis medicine Adakveo® (crizanlizumab) approved by FDA to reduce frequency of pain crises in individuals living with sickle cell disease. [Accessed 08 Augl. 2024] (online) Available from: