Roff Plus 25 mg/500 mg Tablet

Rofecoxib (25mg)+ Paracetamol (500mg)

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Roff Plus 25 mg/500 mg Tablet is a pain relieving medicine. It is used to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 18 Aug 2026 | 01:02 AM (IST)

₹35.8 MRP ₹38.938% off

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General Information

Contains

Rofecoxib (25mg)+ Paracetamol (500mg)

Marketer

Torrent Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Roff Plus 25 mg/500 mg Tablet can be taken with or without food. You should take it regularly as advised by your doctor. Your doctor may change the dose and time between doses according to your pain level and your needs. Do not take more or use it for longer duration than recommended by your doctor.

Some of the common side effects of this medicine include diarrhea, stomach pain, indigestion, flatulence, swelling of hands and feet, and flu-like symptoms. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help with ways to reduce or prevent these side effects by prescribing an alternative medicine or adjusting the dose.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, liver, or have stomach ulcers. To make sure it is safe for you, let your doctor know about all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using this medicine.

Uses of Roff Plus Tablet

Pain relief

Benefits of Roff Plus Tablet

Pain relief
Roff Plus 25 mg/500 mg Tablet is used to relieve pain and inflammation associated with conditions like arthritis, muscle injuries, and other painful disorders. It helps reduce discomfort, improve mobility, and support daily functioning by targeting both pain and swelling effectively.

Side effects of Roff Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Roff Plus

Diarrhea
Stomach pain
Indigestion
Flatulence
Swelling of hands
Feet swelling
Flu-like symptoms

How to use Roff Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Roff Plus 25 mg/500 mg Tablet may be taken with or without food.

How Roff Plus Tablet works

Roff Plus 25 mg/500 mg Tablet is a combination of two medicines: Rofecoxib and Paracetamol. Rofecoxib is a non-steroidal anti-inflammatory drug (NSAID) and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers in the brain that cause pain and fever.

Quick tips

Roff Plus 25 mg/500 mg Tablet is used to treat various painful conditions.
It is better to take it with milk or food to prevent stomach upset.
Do not take it with any other pain medicine without asking your doctor first.
Regularly monitor your blood pressure while taking this medicine, particularly in the first two weeks after starting treatment.
During long-term treatment, your doctor may want to take regular blood tests to monitor your liver function.
Inform your doctor if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease.
Roff Plus 25 mg/500 mg Tablet is used to treat various painful conditions.
It is better to take it with milk or food to prevent stomach upset.
Do not take it with any other pain medicine without asking your doctor first.
Regularly monitor your blood pressure while taking this medicine, particularly in the first two weeks after starting treatment.
During long-term treatment, your doctor may want to take regular blood tests to monitor your liver function.
Inform your doctor if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Roff Plus 25 mg/500 mg Tablet may cause excessive drowsiness when taken with alcohol.

Pregnancy

UNSAFE

Roff Plus 25 mg/500 mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CONSULT YOUR DOCTOR

Roff Plus 25 mg/500 mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CAUTION

Roff Plus 25 mg/500 mg Tablet may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur.

Kidney

CAUTION

Roff Plus 25 mg/500 mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
However, Roff Plus 25 mg/500 mg Tablet contains paracetamol which is considered the safest painkiller for kidney disease patients.

Liver

UNSAFE

Roff Plus 25 mg/500 mg Tablet is unsafe to use in patients with liver disease and should be avoided.
However, the use of Roff Plus 25 mg/500 mg Tablet is not recommended in patients with severe liver disease and active liver disease.

Frequently asked questions

Can I stop taking Roff Plus 25 mg/500 mg Tablet when my pain is relieved?

Roff Plus 25 mg/500 mg Tablet should be continued as advised by your doctor if you are using the medicine for a condition associated with long-term pain. It can be discontinued if you are using it for short-term pain relief.

Can Roff Plus 25 mg/500 mg Tablet cause nausea?

Yes, the use of Roff Plus 25 mg/500 mg Tablet may cause nausea. Eat smaller, more frequent meals to reduce the feeling of nausea. Avoid food that is salty, spicy, fried, or fatty.

Is Roff Plus 25 mg/500 mg Tablet helpful in relieving stomach pain?

No, Roff Plus 25 mg/500 mg Tablet should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.

Is Roff Plus 25 mg/500 mg Tablet a painkiller?

Yes, Roff Plus 25 mg/500 mg Tablet is a pain killer and prescription medicine that is used to relieve signs and symptoms of arthritis, and acute pain in adults.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Torrent Pharmaceuticals Ltd
Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India

Vendor Details

Country of origin: India

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Why we need a prescription?

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Pain Analgesics

Anti Rheumatics Non Steroidal Systemic

Roff Plus 25 mg/500 mg Tablet

Roff Plus 25 mg/500 mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Roff Plus Tablet

Benefits of Roff Plus Tablet

Side effects of Roff Plus Tablet

How to use Roff Plus Tablet

How Roff Plus Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Can I stop taking Roff Plus 25 mg/500 mg Tablet when my pain is relieved?

Can Roff Plus 25 mg/500 mg Tablet cause nausea?

Is Roff Plus 25 mg/500 mg Tablet helpful in relieving stomach pain?

Is Roff Plus 25 mg/500 mg Tablet a painkiller?

Fact Box

Habit Forming

Therapeutic Class

References

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Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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