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Rofact MR Tablet is a pain relieving medicine. It is used to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 23 Jan 2026 | 10:15 AM (IST)
₹51.8 MRP ₹57.3110% off 
As per Ministry of Health and Family Welfare
Gurgaon
 
 
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General Information

Contains

Rofecoxib (50mg)+ Tizanidine (NA)

Marketer

Sun Pharmaceutical Industries Ltd

Storage

Store below 30°C
The content is shown in English
Rofact MR Tablet image
Rofact MR Tablet image

Product introduction

Rofact MR Tablet can be taken with or without food. You should take it regularly as advised by your doctor. Your doctor may change the dose and time between doses according to your pain level and your needs. Do not take more or use it for a longer duration than recommended by your doctor.

Some of the common side effects of this medicine include diarrhea, stomach pain, indigestion, dryness in mouth, and flatulence. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help with ways to reduce or prevent these side effects by prescribing an alternative medicine or adjusting the dose.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, liver, or have stomach ulcers. To make sure it is safe for you, let your doctor know about all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using this medicine.

Uses of Rofact MR Tablet

Benefits of Rofact MR Tablet

Pain relief
Pain, especially when linked with muscle spasms or inflammation, can limit daily activity and reduce quality of life. Rofact MR Tablet works by easing inflammation and relaxing tight muscles. It helps reduce swelling, pain, and relieves muscle spasms. This medicine provides relief from muscular and joint-related pain, helping restore movement and comfort.

Side effects of Rofact MR Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Rofact MR
  • Diarrhea
  • Stomach pain
  • Indigestion
  • Dryness in mouth
  • Flatulence
  • Swelling of hands
  • Feet swelling
  • Weakness
  • Sleepiness
  • Dizziness
  • Flu-like symptoms

How to use Rofact MR Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rofact MR Tablet may be taken with or without food.

How Rofact MR Tablet works

Rofact MR Tablet is a combination of two medicines: Rofecoxib and Tizanidine, which relieves pain and relaxes the muscles. Rofecoxib is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Tizanidine is a muscle relaxant. It works on the centers in the brain and spinal cord to relieve muscle stiffness or spasm and to improve pain and movement of muscles.

Quick tips

  • Rofact MR Tablet is used to reduce pain and inflammation in various conditions.
  • It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Rofact MR Tablet as it may cause excessive drowsiness. 
  • Regularly monitor your blood pressure while taking this medicine, particularly in the first two weeks after starting treatment.
  • Inform your doctor if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease.
  • Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Rofact MR Tablet helps relieve pain due to muscle spasm.
  • Take it without food for quicker relief.
  • It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Rofact MR Tablet as it may cause excessive drowsiness. 
  • Regularly monitor your blood pressure while taking this medicine, particularly in the first two weeks after starting treatment.
  • Inform your doctor if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease.
  • Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Rofact MR Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

UNSAFE
Rofact MR Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Rofact MR Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Rofact MR Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Rofact MR Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Rofact MR Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Rofact MR Tablet is not advised in patients with severe liver disease. Liver function tests are recommended before the start of treatment and then on a regular basis as advised.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. Rofecoxib. [Accessed 02 Apr. 2019] (online) Available from:
  2. Tizanidine. Ardsley, NY: Acorda Therapeutics Inc; 1996 [revised 2013]. [Accessed 02 Apr. 20191] (online) Available from:
  3. ScienceDirect. Rofecoxib. [Accessed 02 Apr. 2019] (online) Available from:
  4. Tizanidine. Hawthorne, NY: Acorda Therapeutics Inc; 2006]. [Accessed 02 Apr. 2019] (online) Available from:
  5. ScienceDirect. Rofecoxib. [Accessed 02 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135 || Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205

Vendor Details

Country of origin: India

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