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Composition for ROFACT MR

Rofecoxib(50 mg),Tizanidine(NA)

food interaction for ROFACT MR

alcohol interaction for ROFACT MR

pregnancy interaction for ROFACT MR

lactation interaction for ROFACT MR

food
alcohol
pregnancy
lactation
There is no data available. Please consult doctor before consuming the drug.
Rofact mr tablet may cause excessive drowsiness and calmness with alcohol.
UNSAFE
Rofact mr tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Rofact mr tablet is probably unsafe to use during breastfeeding. Please consult your doctor.
UNSAFE

SALT INFORMATION for ROFACT MR

Rofecoxib(50 mg)

Uses

Rofecoxib is used in the treatment of osteoarthritis, rheumatoid arthritis, menstrual pain and migraine.

How it works

Rofecoxib belongs to a group of medicines called COX-2 selective nonsteroidal anti-inflammatory drugs (NSAIDs). It works by inhibiting certain chemical called prostaglandin which is responsible for pain and inflammation.

Common side effects

Abdominal pain, Abnormal liver function tests, Headache, Heart attack, Heartburn, Hepatitis (viral infection of liver), Increased blood pressure, Renal disorder, Nausea, Diarrhoea, Bloating, Vomiting
Tizanidine(NA)

Uses

Tizanidine is used for muscle relaxation.

How it works

Tizanidine belongs to group of medicines called centrally acting muscle relaxants. It acts by blocking the nerve impulses which excites the muscles reducing their tone. As a result, the muscle relaxes and there is reduction of pain and spasms.

Common side effects

Vomiting, Nausea, Abdominal pain, Skin rash, Allergic reaction, Altered vision, Back pain, Bruise, Bleeding, Dizziness, Depression, Drowsiness, Nervousness, Dry mouth, Fatigue, Heartburn, Altered heart rate, Bradycardia, Increased sweating, Influenza like symptoms, Loss of appetite, Muscle cramp, Tingling sensation, Auditory hallucination, Visual hallucination, Weakness, Yellow discoloration of skin, Yellow discoloration of eye, Constipation, Diarrhoea

SUBSTITUTES for ROFACT MR

No substitutes found

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Expert advice for ROFACT MR

  • Inform your doctor before taking the drug if you are allergic to aspirin or other NSAIDs.
  • Stop taking rofecoxib and seek immediate medical attention if you develop: abdominal pain, tenderness, or discomfort; nausea; blood in your vomit; bloody, black, or tarry stools; unexplained weight gain; swelling or water retention; fatigue or lethargy; a skin rash; itching; yellowing of your skin or eyes; or unusual bruising or bleeding.
  • Tell your doctor if you have asthma, stomach problems such as ulcers or bleeding, kidney disease, liver disease, angina (chest pain), heart attack, or a blocked artery in the heart, heart failure, high blood pressure.

Frequently asked questions for ROFACT MR

Rofecoxib

Q.Is rofecoxib a narcotic?
No, rofecoxib is a nonsteroidal anti-inflammatory drugs (NSAIDs)

Q.Is rofecoxib deadly?
Rofecoxib is relatively safe if used as prescribed. In case of any side-effects, please consult your doctor

Q.How does rofecoxib work?
Rofecoxib belongs to a group of medicines called COX-2 selective nonsteroidal anti-inflammatory drugs (NSAIDs). It works by inhibiting certain chemical called prostaglandin which is responsible for pain and inflammation.

Tizanidine

Q.Does tizanidine contain sulfa or asprin?
Tizanidine does not contain sulfa and aspirin

Q.Is tizanidine an opiate, NSAID, blood thinner, controlled substance, or muscle relaxer?
Tizanidine is not an opiate, NSAID, blood thinner or a controlled substance. It is a muscle relaxant

Q.Is tizanidine like valium?
Valium is a brand name for drug diazepam. It is also used as a muscle relaxant, but both have different functions. Please consult your doctor before taking the drug

Q.Is tizanidine stronger than Flexeril?
Flexeril is a brand name for drug cyclobenzaprine, which is also used as a muscle relaxant. Effect of the drug may vary upon individual response. Please consult your doctor before taking the drug

Q.Is tizanidine water soluble?
Tizanidine is a lipid-soluble drug; it is only slightly soluble in water and methanol

Q.Is tizanidine gluten free?
Tizanidine is gluten free. However, please refer to package insert of the prescribed brand before use

Q.Can I take tizanidine or Zanaflex for menstrual cramps, headaches, or anxiety?
No, you cannot take tizanidine or Zanaflex (which contains tizanidine) for menstrual cramps, headaches, or anxiety. Please consult your doctor before taking the drug

Q.Does tizanidine cause weight loss or keep you awake (insomnia)?
You may experience insomnia or weight loss with the use of tizanidine. Few people may experience excessive sleepiness. If you experience such side effects, consult your doctor

Q.Can I take tizanidine with Aleve (naproxen), Ambien (zolpidem), Norco (acetaminophen and hydrocodone), Tylenol (paracetamol), Valium (diazepam), or Xanax (alprazolam)?
You may take Aleve and Tylenol with tizanidine, but Ambien, Norco, Valium, and Xanax should not be given with tizanidine. Consult your doctor before simultaneous use

Q.Can I take tizanidine with prednisone, ibuprofen, tramadol, or oxycodone?
Tizanidine may be taken with prednisone or ibuprofen, but tramadol or oxycodone with tizanidine may increase their side effects. Consult your doctor before simultaneous use

Q.Does tizanidine show on a drug test?
No, tizanidine does not show on a drug test. Only narcotic drugs show up on a drug test.

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Content on this page was last updated on 23 August, 2015, by Dr. Varun Gupta (MD Pharmacology)