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Ril-Plus Tablet

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Product introduction

Ril-Plus Tablet is a combination of two antiplatelet medicines or blood thinner used to reduce the formation of harmful blood clots in blood vessels. It is used to prevent a heart attack or stroke in people with heart disease. It is also used to treat acute coronary syndrome (ACS).

Ril-Plus Tablet should be taken with food regularly at a fixed time each day. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. Lifestyle changes like low-fat diet, exercise and not smoking may help this medicine to work better.

Common side effects of this medicine include indigestion, bruising, and nosebleeds. This medicine increases your risk of bleeding, so it is important to be careful while shaving, cutting nails and using sharp objects. Usually, it is advisable to avoid alcohol intake while taking this medicine.

Before taking this medicine, tell your doctor if you have any liver or kidney disease. You must tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.

Uses of Ril-Plus Tablet

  • Prevention of heart attack and stroke
  • Treatment of Acute coronary syndrome

Benefits of Ril-Plus Tablet

In Prevention of heart attack and stroke

Ril-Plus Tablet is a combination of two antiplatelet medicines or blood thinners. It prevents blood from clotting inside the veins and arteries. This helps the blood flow freely around your body thereby preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). Both these medicines together prevent the formation of blood clots and also prevent the existing ones from growing bigger in size. Take it regularly and make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine. Keep taking it even if you feel well.

In Treatment of Acute coronary syndrome

Ril-Plus Tablet helps reduce clot formation and prevents platelets from sticking together to form clots. This way the medicine provides a potent anti-clotting effect, maintaining blood flow in narrowed arteries, which is crucial for preventing heart attacks and other serious cardiovascular events in ACS patients.

Side effects of Ril-Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ril-Plus

  • Bruise
  • Gastrointestinal bleeding
  • Increased bleeding tendency
  • Nosebleeds

How to use Ril-Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ril-Plus Tablet is to be taken with food.

How Ril-Plus Tablet works

Ril-Plus Tablet is a combination of two antiplatelet medicines: Aspirin and Clopidogrel which prevent heart attack. They work by preventing the platelets from sticking together and decrease the formation of harmful blood clots. It is also used to treat acute coronary syndrome (ACS).

Safety advice

It is unsafe to consume alcohol with Ril-Plus Tablet.
Ril-Plus Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
Ril-Plus Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Ril-Plus Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Ril-Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment of Ril-Plus Tablet may be needed. Please consult your doctor.
Use of Ril-Plus Tablet is not recommended in patients with severe kidney disease.
Ril-Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Ril-Plus Tablet may be needed. Please consult your doctor.
Use of Ril-Plus Tablet is not recommended in patients with severe liver disease.

What if you forget to take Ril-Plus Tablet?

If you miss a dose of Ril-Plus Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

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Quick tips

  • You have been prescribed Ril-Plus Tablet to lower your risk of heart attack and stroke.
  • Take it with food to avoid an upset stomach. 
  • It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails or using sharp objects.
  • Let your doctor know you are taking Ril-Plus Tablet before undergoing any surgical procedure.

Fact Box

Habit Forming
Therapeutic Class

Patient concerns

Fast symbol of heart attack and stroke
Dr. Nabajit Talukdar
risk factors undue fatigue chest pain etc
My father had a heart attack on 3-feb -2016 . In emergency we took him to nearby hospital for treatment . There he was given treatment for the Myocardial Infarction . After few days , we took him to Max hospital , Patparganj . A lot of tests like ECG , Blood tests , Echo , Stress Echo were conducted and echo showed LVEF ( 45 % ) and doctor asked to go with medicines . We are not sure that we should go for the Cardiac Angiograph .
Dr. Nabajit Talukdar
needs a coronary angiogram can call 9XXXXXX

User feedback


Q. Why have I been prescribed Ril-Plus Tablet?

You may have been prescribed Ril-Plus Tablet if you had a heart attack, were treated with stents in your coronary arteries, or had coronary artery bypass graft surgery (CABG).

Q. Is Ril-Plus Tablet a blood thinner?

Yes, Ril-Plus Tablet is a type of blood thinner. It works by preventing platelets (type of blood cells) from sticking together and forming clots. This action of Ril-Plus Tablet helps in preventing conditions like heart attack or stroke in people with heart disease, who have recently suffered a heart attack or severe heart-related chest pain (unstable angina).

Q. How long do I need to take Ril-Plus Tablet after stent insertion?

Your doctor will suggest the exact duration for which you may have to take Ril-Plus Tablet. The duration will be decided after considering various factors like the illness you are being treated for, type of stent inserted, any episodes of bleeding experienced by you during treatment, etc. Usually, Ril-Plus Tablet is prescribed for a minimum duration of 1 year. However, it is advised to follow your doctor's advice precisely to get maximum benefit of Ril-Plus Tablet. Do not stop the medication on your own, consult your doctor first. Sudden discontinuation may increase the chances of clot formation in the stent, heart attack and can even lead to death.

Q. Can I drink alcohol while taking Ril-Plus Tablet?

It is not advised to take alcohol while taking Ril-Plus Tablet, as alcohol may increase your chance of stomach bleeding. As a result, you may vomit blood (which may be bright red blood or black/dark brown like coffee grounds) or you may have bloody or black tarry stools. Discuss with your doctor if you are not sure.

Q. What is the most important information I need to know about Ril-Plus Tablet?

Ril-Plus Tablet may cause serious or life-threatening bleeding. Moreover, you may bruise easily and it may take longer than usual for bleeding to stop even if you have a minor injury like a small cut while shaving. Get emergency medical help if you notice excessive or prolonged bleeding. You should inform your doctor if you notice black tarry stools or if there is blood in the urine. Be vigilant on any signs of stroke such as sudden numbness or weakness (one side or both sides of the body), difficulty walking, mental confusion, slurred speech, dizziness and any unexplained headache. Contact your doctor immediately if you develop any such signs of stroke as stroke is an uncommon side effect of Ril-Plus Tablet and needs urgent medical attention as it can otherwise be fatal.

Q. Do I need to stop Ril-Plus Tablet before surgery?

Your doctor will decide whether you need to stop taking Ril-Plus Tablet before any surgery or treatment or not. Usually, if a surgery or treatment is planned beforehand, the doctor may stop Ril-Plus Tablet a few days (usually 7 days) before the surgery or treatment owing to the increased risk of bleeding during the procedure. You should not stop taking Ril-Plus Tablet on your own without discussing it with your doctor.

Q. Who should not take Ril-Plus Tablet?

Ril-Plus Tablet is not recommended for people who are allergic to it or any of its ingredients. Do not take Ril-Plus Tablet if you have or ever had severe liver disease, stomach ulcers, bleeding in the brain (stroke or a transient ischemic attack, also known as TIA), or if you have a bleeding disorder known as hemophilia (disease in which blood does not clot normally). Additionally, avoid taking Ril-Plus Tablet if you are trying to get pregnant, already pregnant, or breastfeeding.

Q. What if I forget to take a dose of Ril-Plus Tablet?

If you forget to take a dose of Ril-Plus Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

Q. What should I avoid while taking Ril-Plus Tablet?

Avoid activities that may increase your chances of bleeding. Be extra careful while shaving or brushing your teeth to prevent bleeding. Also, you should avoid taking painkillers, but if you need to take one like ibuprofen for joint pain, headache, backache, etc. then consult your doctor first. This is because taking pain killers with Ril-Plus Tablet may increase your chances of developing a stomach ulcer and bleeding. Refrain from taking excessive alcohol with Ril-Plus Tablet as it can irritate your stomach and lead to a stomach ulcer as well.

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  1. MedIndia. Clopidogrel. [Accessed 12 Apr. 2019] (online) Available from:External Link
  2. NHS. Low-dose aspirin. [Accessed 11 Apr. 2019] (online) Available from:External Link
  3. Clopidogrel bisulfate. New York, New York: Bristol-Myers Squibb/Sanofi Pharmaceuticals Partnership; 2006. [Accessed 12 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Artus Pharma Pvt Ltd
Address: 16/A Khadayata Society B/H Balvatika Kankana Maninagar Ahmedabad 380008 Gujrat India
Country of origin: India

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