
Repile Cream
Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 04 Jan 2026 | 08:36 PM (IST)
Repile Cream is a prescription medicine having a combination of medicines that is used to treat anal fissures. It provides relief from redness, swelling and itching. It decreases the pain sensation. It helps in softening the skin.
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General Information
The content is shown in English



Product introduction
Repile Cream should be used in the dose and duration as advised by your doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. It is for external use only.
Do not use this medicine more than the recommended dose. Inform your doctor if you have known allergies from this medicine. The common side effects of this medicine include burning, irritation, itchiness, and redness at the application site.
If these side effects or any other symptoms which you think are because of this medicine persist for a longer duration, please consult your doctor. Inform your doctor if you are pregnant or are suffering from any other disease. This medicine is safe to use in breastfeeding mothers.
Uses of Repile Rectal Cream
Benefits of Repile Rectal Cream
Treatment of Anal fissure
Anal fissure is a small tear in the lining of the anus that may occur when you pass hard stools. Anal fissures typically cause pain while passing stools. Repile Cream decreases pain sensation at the affected area and helps in passing the stools easily. It also reduces swelling, redness, itching and irritation in the anal area. It soothes the area and gives relief from burning sensation. Apply Repile Cream as prescribed for faster healing. Make sure to avoid spicy, oil-rich food and take plenty of fibers to aid in digestion and thus prevent hard stools.
Anal fissure is a small tear in the lining of the anus that may occur when you pass hard stools. Anal fissures typically cause pain while passing stools. Repile Cream decreases pain sensation at the affected area and helps in passing the stools easily. It also reduces swelling, redness, itching and irritation in the anal area. It soothes the area and gives relief from burning sensation. Apply Repile Cream as prescribed for faster healing. Make sure to avoid spicy, oil-rich food and take plenty of fibers to aid in digestion and thus prevent hard stools.
Side effects of Repile Rectal Cream
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Repile
- Application site reactions (burning, irritation, itching and redness)
How to use Repile Rectal Cream
This medicine is for external use only. Use it in the dose and duration as advised by your doctor.
How Repile Rectal Cream works
Repile Cream is a combination of four medicines: Hydrocortisone, Zinc Oxide, Lidocaine, and Allantoin, that helps treat anal fissures . Hydrocortisone is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Zinc Oxide has astringent and antiseptic action. Lidocaine is a local anesthetic which works by blocking pain signals from the nerves to the brain thereby decreasing pain sensation. Allantoin is a skin protectant that moisturizes and softens the skin.
Quick tips
- Repile Cream is prescribed to get relief from pain and swelling in the rectal area due to fissures.
- Do not take any other laxative along with Repile Cream without consulting your doctor.
- Sometimes certain medicines like iron tablets, antibiotics might make your stools hard and difficult to pass. Inform your doctor if you are taking any of them.
- Apart from using Repile Cream, you can indulge in warm baths. It may help soothe the area and thus may ease the pain.
- Don't ignore the feeling of needing to pass stools. Some people suppress this feeling and put off going to the toilet until later. This may result in bigger and harder stools forming that are more difficult to pass later.
- A fibre rich diet (wholegrain breads and cereals, fruit and green leafy vegetables) with six to eight full glasses of water each day and daily exercise are important in maintaining healthy bowel function.
Safety advice

Alcohol
No interaction found/established

Pregnancy
CONSULT YOUR DOCTOR
The safety of Repile Cream during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
SAFE IF PRESCRIBED
Repile Cream may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving
No interaction found/established

Kidney
SAFE IF PRESCRIBED
Repile Cream is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.

Liver
SAFE IF PRESCRIBED
Repile Cream is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.
Frequently asked questions
Repile Cream is used to relieve swelling, pain, itching, and discomfort caused by hemorrhoids, anal fissures, and other minor rectal irritations. It helps reduce inflammation, soothe irritated skin, and promote healing.
Individuals should avoid Repile Cream if they are allergic to any of its ingredients, have viral, bacterial, or fungal infections in the rectal area, have tuberculosis, or have certain skin conditions around the anus.
Repile Cream is intended for short-term use to manage symptoms. Long-term or frequent use without medical advice may lead to skin thinning or irritation.
You should check with your doctor before using Repile Cream with other topical treatments to avoid irritation or reduced effectiveness.
You should wash and dry the affected area gently before applying Repile Cream, avoid contact with eyes or mouth, and use only the amount recommended by your doctor.
Although they are rare, allergic reactions such as severe itching, rash, swelling, or burning can occur with Repile Cream use. If these symptoms appear, stop using the cream and seek medical advice immediately.
If you have chronic skin conditions like eczema or psoriasis near the rectal area, consult your doctor before using Repile Cream to ensure it is safe for you.
Yes, Repile Cream provides rapid numbing of the affected area, often giving pain relief within minutes. Repile Cream also works on healing and reducing inflammation over time.
Fact Box
Habit Forming
No
Therapeutic Class
UROLOGY
References
- Hydrocortisone+Zinc Oxide+Lidocaine+Allantoin [Summary of Product Characteristics]. Thane, India: Kremoint Pharma Pvt. Ltd.; 2024.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Colinz Laboratories Ltd
Address: A/101, Pratik Estate, Next to Fortis Hospital, Mulund Link Road, Mumbai-400078.
Address: A/101, Pratik Estate, Next to Fortis Hospital, Mulund Link Road, Mumbai-400078.
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
Why we need a prescription?
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Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose
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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945














