Reliseal Kit

Aprotinin (3000KIU)+ Fibrinogen (70mg)+ Thrombin (500IU)

Genuine

Authenticity Assured

Prescription

required

Cold stored

Stored between 2-8°C

Reliseal Kit is a combination medicine used to prevent bleeding in a variety of surgical procedures. It works by preventing the breakdown of clots and control excessive bleeding. It also helps in healing wounds.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 13 Apr 2026 | 05:40 PM (IST)

₹3621 MRP ₹3970.319% off

Gurgaon

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General Information

Contains

Aprotinin (3000KIU)+ Fibrinogen (70mg)+ Thrombin (500IU)

Marketer

Reliance Formulation Pvt Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Reliseal Kit is to be administered by a doctor or a nurse in a clinical setting of a hospital. Do not self administer this medicine at home. The dose and duration of the medicine will depend on the severity of your condition. Make sure to get the complete dose of the medicine for full benefit.

Some common side effects of this medicine include fever, headache, increased heart rate, anemia, low blood platelets, pleuritis, asthma, pneumonia, acute kidney failure, nausea, vomiting, dizziness, constipation, and allergy. Let your doctor know if any of these side effects do not go away on their own or get worse.

Before receiving this medicine, let your doctor know if you have any bleeding disorders or are on any blood-thinning medications. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. To make sure it is safe for you, let your doctor know about all the medicines you are taking.

Uses of Reliseal Injection

Treatment of Bleeding

Benefits of Reliseal Injection

Treatment of Bleeding
Reliseal Kit helps in controlling bleeding by speeding up blood clotting. It helps to prevent excessive loss of blood, stops bleeding and enhances the healing process. This helps prevent complications of excessive bleeding such as hemorrhage.

Side effects of Reliseal Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Reliseal

Fever
Headache
Increased heart rate
Anemia (low number of red blood cells)
Low blood platelets
Pleuritis (inflammation of the tissues that line the lungs and chest cavity)
Asthma
Pneumonia
Kidney damage
Nausea
Vomiting
Dizziness
Constipation
Allergy

How to use Reliseal Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Reliseal Injection works

Reliseal Kit is a combination of three medicines: Aprotinin, Fibrinogen and Thrombin. They work by preventing the breakdown of clots and control excessive bleeding.

Quick tips

Reliseal Kit helps in controlling excessive bleeding.
Your doctor may monitor your vision regularly while you are taking this medicine.
Inform your doctor if you do not notice any improvement within 3 days of the treatment.
You will be monitored carefully for any allergic reaction to the medicine.
Inform your doctor if you have kidney problems.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Reliseal Kit. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Reliseal Kit during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.

Driving

NOT RELEVANT

Not relevant, as Reliseal Kit is intended for use in hospitalized patients.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Reliseal Kit in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Reliseal Kit should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

What is Reliseal Kit used for?

Surgeons use Reliseal Kit on bleeding surfaces during surgery to improve hemostasis (help blood clot), support sutures, and act as a tissue glue for sealing or adhesion when standard techniques alone are not sufficient.

How is Reliseal Kit given, and who gives it?

Reliseal Kit is prepared and applied by trained surgeons in the operating room directly onto the tissue surface. It is for epilesional use only (on the wound surface), not into a vein or artery.

Who should not receive Reliseal Kit?

Individuals should not receive Reliseal Kit if they have a known allergy to any component (human fibrinogen, human factor XIII, bovine aprotinin, thrombin, calcium chloride) or excipients, or if there is arterial or strong venous bleeding where this medicine is not appropriate. It must never be injected into a blood vessel.

What are the most important safety warnings of Reliseal Kit?

Avoid injecting Reliseal Kit into a blood vessel, as this can cause life‑threatening clots and widespread clotting (DIC). Severe allergic reactions, including anaphylaxis, may occur—especially in those previously exposed due to the presence of bovine aprotinin, so prior use should be recorded. Care should also be taken to protect areas outside the target site to prevent unwanted tissue adhesion.

What serious side effects of Reliseal Kit need urgent medical help?

Seek urgent medical help if you experience signs of serious side effects of Reliseal Kit, such as severe allergic reaction, including rash, hives, chest tightness, wheezing, swelling of the face or tongue, or sudden breathing difficulty, as these may lead to anaphylactic shock. After endoscopic treatment for GI bleeding, new stomach pain, nausea, or vomiting within 1 to 3 days may indicate a wall hematoma or, rarely, pancreatitis and should be checked immediately. Also, accidental injection into a blood vessel can cause serious blood clots and requires emergency care.

What should caregivers and patients remember post‑operation after Reliseal Kit use?

Reliseal Kit remains in place and is naturally broken down by the body as healing advances. Unlike some medicines or agents, it is not routinely removed. Report any unusual allergic symptoms or severe abdominal pain after endoscopic GI treatment promptly to the surgical team.

Fact Box

Habit Forming

Therapeutic Class

BLOOD RELATED

References

User feedback

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Others

75%

Bleeding

25%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Reliance Formulation Pvt Ltd
Address: Reliance Formulation Private Limited, 201-202, Anand Mangal-3, Rajnagar Club Road Ambabadi, Ahmedabad-380015, Gujarat, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Reliseal Kit

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Reliseal Injection

Benefits of Reliseal Injection

Side effects of Reliseal Injection

How to use Reliseal Injection

How Reliseal Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Reliseal Kit used for?

How is Reliseal Kit given, and who gives it?

Who should not receive Reliseal Kit?

What are the most important safety warnings of Reliseal Kit?

What serious side effects of Reliseal Kit need urgent medical help?

What should caregivers and patients remember post‑operation after Reliseal Kit use?

Fact Box

Habit Forming

Therapeutic Class

References

User feedback

What are you using Reliseal Injection for?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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