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R-Loc D Tablet
Domperidone (10mg)+ Ranitidine (150mg)
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R-Loc D Tablet is a combination medicine used to treat acid reflux (GERD) and indigestion. It works by reducing excess stomach acid and improving the movement of food through the stomach and intestines. This helps relieve symptoms such as heartburn, acidity, bloating, and discomfort after meals.
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)
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30 tablets
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General Information
The content is shown in English






Product introduction
Take R-Loc D Tablet in the dose and duration advised by your doctor. Finish the full course of treatment even if you feel better. A high dose or overdose may have harmful effects on the body.
There is limited data on the side effects of R-Loc D Tablet. Let your doctor know if you experience any symptoms while taking R-Loc D Tablet. They may be able to suggest ways to treat or manage the side effects.
Before taking the medicine, always consult your doctor if you are pregnant or breastfeeding. Let your doctor also know if you are suffering from any severe stomach, liver, kidney, or any known diseases. Do not take R-Loc D Tablet if you have a known history of allergic reactions to any of the components of this medicine.
Uses of R-Loc D Tablet
Benefits of R-Loc D Tablet
Treatment of Indigestion
R-Loc D Tablet provides relief from indigestion and related symptoms like bloating, nausea, and a feeling of fullness after meals. It enhances the natural movement of the stomach and intestines, allowing food to pass more easily through the digestive tract. Regular use as prescribed helps restore normal digestion and reduces discomfort after eating.
R-Loc D Tablet provides relief from indigestion and related symptoms like bloating, nausea, and a feeling of fullness after meals. It enhances the natural movement of the stomach and intestines, allowing food to pass more easily through the digestive tract. Regular use as prescribed helps restore normal digestion and reduces discomfort after eating.
Treatment of Gastroesophageal reflux disease (Acid reflux)
R-Loc D Tablet helps relieve symptoms of gastroesophageal reflux disease (GERD), such as heartburn, acidity, and discomfort after meals. It works by reducing excess stomach acid and improving the movement of food through the stomach, preventing acid from flowing back into the food pipe. This helps you eat more comfortably and improves overall digestive health.
R-Loc D Tablet helps relieve symptoms of gastroesophageal reflux disease (GERD), such as heartburn, acidity, and discomfort after meals. It works by reducing excess stomach acid and improving the movement of food through the stomach, preventing acid from flowing back into the food pipe. This helps you eat more comfortably and improves overall digestive health.
Side effects of R-Loc D Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of R-Loc D
- Limited data available
How to use R-Loc D Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. R-Loc D Tablet is to be taken on an empty stomach.
How R-Loc D Tablet works
R-Loc D Tablet is a combination of domperidone and ranitidine. Domperidone is a prokinetic that helps improve digestion by increasing the movement of the stomach and intestines, allowing food to pass more easily, and preventing reflux. Ranitidine is an H2 blocker that reduces stomach acid production, providing relief from acid-related conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers.
All substitutes for R-Loc D Tablet
For information purposes only. Consult a doctor before taking any medicine.
Rantac-D Tablet
by J B Chemicals and Pharmaceuticals Ltd
₹3.44/tablet
131% costlier
Raspar D 10mg/150mg Tablet
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₹2.12/tablet
42% costlier
Rantac-Dom Tablet
by J B Chemicals and Pharmaceuticals Ltd
₹3.44/tablet
131% costlier
Ranic Plus 10mg/150mg Tablet
by Tunic Healthcare
₹1.87/tablet
26% costlier
Periran 10 mg/150 mg Tablet
by Mercury Laboratories Ltd
₹2.04/tablet
37% costlier
Quick tips
- Swallow whole with water; do not crush, chew, or break, as this may affect how the medicine works.
- Avoid alcohol and caffeine, as these can irritate your stomach and may reduce the effectiveness of the medicine.
- Be cautious if you have heart, liver, or kidney conditions, as this medicine may not be safe for such individuals.
- Stick to the prescribed dose and do not take extra doses even if you miss one. Overuse may lead to side effects like dizziness, dry mouth, or diarrhea.
- Avoid taking soft drinks and citrus fruits like oranges and lemons while taking this medicine. These can irritate the stomach and increase acid secretion.
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with R-Loc D Tablet

Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of R-Loc D Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding
SAFE IF PRESCRIBED
R-Loc D Tablet may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving
CONSULT YOUR DOCTOR
It is not known whether R-Loc D Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney
CONSULT YOUR DOCTOR
There is limited data available on the use of R-Loc D Tablet in patients with kidney disease. Please consult your doctor.

Liver
CONSULT YOUR DOCTOR
There is limited data available on the use of R-Loc D Tablet in patients with liver disease.
Frequently asked questions
Take R-Loc D Tablet exactly as directed by your doctor. It can be taken with or without food. To prevent heartburn and acid indigestion, take it 30-60 minutes before eating food or drinking beverages, as that can lead to indigestion. Follow all directions as advised.
Serious side effects are rare but can occur if you take a higher-than-recommended dose. You could have stomach pain that seems to be getting worse (sign of an inflamed liver or pancreas), back pain, fever, pain while peeing, or blood in your urine (signs of kidney problems), rash, and a slow or irregular heartbeat.
Yes, the use of R-Loc D Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry.
Speak with your doctor if you conceive while taking R-Loc D Tablet. Let your doctor know even if you are planning a baby. Some studies have shown that its use is unsafe during pregnancy, as it may harm the fetus.
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, or other people.
Fact Box
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
References
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Disclaimer
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Zydus Cadila
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver R-Loc D Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver R-Loc D Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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