Pyrope NT 75mg/10mg Tablet


Overview

Uses of Pyrope NT Tablet

Pyrope NT 75mg/10mg Tablet is used in the treatment of neuropathic pain.

Pyrope NT Tablet side effects

Common
  • Constipation
  • Difficulty in urination
  • Weight gain
  • Sleepiness
  • Dizziness
  • Tiredness
  • Blurred vision
  • Dryness in mouth
  • Increased heart rate
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Uncoordinated body movements

How to use Pyrope NT Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pyrope NT 75mg/10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Pyrope NT Tablet works

Pyrope NT 75mg/10mg Tablet is a combination of two medicines: Pregabalin and Nortriptyline. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves).

Pyrope NT Tablet related warnings

Alcohol
CAUTION
Pyrope NT 75mg/10mg Tablet may cause excessive drowsiness and calmness with alcohol.
Pregnancy
WEIGH RISKS VS BENEFITS
Pyrope NT 75mg/10mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
CAUTION
Pyrope NT 75mg/10mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
Do not drive unless you are feeling well.
As Pyrope NT 75mg/10mg Tablet may affect your alertness which may affect your ability to drive.
Kidney
CAUTION
Pyrope NT 75mg/10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pyrope NT 75mg/10mg Tablet may be needed. Please consult your doctor.
Liver
Pyrope NT 75mg/10mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pyrope NT 75mg/10mg Tablet may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Pyrope NT 75mg/10mg Tablet
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Patient Concerns

Questions Related to Pyrope NT

I suffered from brain stroke. How long can I use gabapentin 300 mg tablets ?
Dr. Anshul Varshney
General Physician
Hello, Welcome to 1mg. I am Anshul Varshney for your help. This medicine is used to calm down the neuropathic pain. You may take it till you feel better. Later your doctor may reduce the dose and stop it.
I m suffering due to pain in left testis, so I visited pgimer Chandigarh in urology deptt. There I had gone for dopler ultrasound testis and its reports are normal Now whenever I lay down at bed I felt a smaal lump in testis,when I touchdown it, the pain radiates in whole left testis Now I m feeling pain sometimes in both tastis Is it a sign of early vericoseal Or something else Pls. Suggest
Dr. Pranay Gandhi
Sexologist
it is a neuropathic pain and it won't show any abnormality in USG. i am worried about the lump u r talking about. its better if u consult a surgeon, PGIMER UROLOGY is the best place to go for examination. if they say its normal, its normal. for pain take pregaba m 1 od
Do you have any questions related to Pyrope NT 75mg/10mg Tablet?

User Feedback


FAQs

Q. What is Pyrope NT?
Pyrope NT is a combination of two medicines: Pregabalin and Nortriptyline. This medicine is useful in the treatment of nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain. Thereby, decreasing the pain sensation.
Q. Can I stop taking Pyrope NT when my pain is relieved?
No, you should not stop taking Pyrope NT even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Pyrope NT, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the dose before you stop the medication completely.
Q. How to manage weight gain associated with the use of Pyrope NT?
Pyrope NT can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight.. However, preventing weight gain is easier than losing increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). DO not eat foods that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
Q. Can the use of Pyrope NT cause sleepiness or drowsiness?
Yes, Pyrope NT may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while taking this medicine.
Q. Can the use of Pyrope NT affect my sexual life?
The use of Pyrope NT can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while intercourse. If you experience these problems, discuss them with your doctor but do not stop taking Pyrope NT.
Q. Are there any serious side effects associated with the use of Pyrope NT?
Serious side effects because of Pyrope NT are uncommon and rare. Consult your doctor if you notice any of the following: changes in body temperature, difficulty in breathing, increased heartbeat (palpitations), weakness, unsteadiness when walking, reduced coordination or slowed reactions, unusual changes in mood or behavior (such as restlessness, nervousness or excitement), signs of depression, seeing or hearing things that are not there, irrational thinking, blurred or double vision, uncontrollable jerky eye movements, difficulty seeing, signs of frequent infections such as fever, severe chills, sore throat or mouth ulcers. These side effects are uncommon but may be serious and need urgent medical attention.
Q. How long will the Pyrope NT take to act?
An initial benefit with Pyrope NT may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see full benefit. It may even take longer in some patients.
Q. What if I forget to take Pyrope NT?
If you forget to take the scheduled dose of Pyrope NT and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects due to overdosage. If you are not sure what to do, consult your doctor about how to manage a situation like this.
Q. What if I take too much of this drug by mistake?
In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteadiness while walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.
Q. Will Pyrope NT be more effective if a higher than the recommended dosage is taken?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Q. Is there anything I need to avoid while taking Pyrope NT?
Pyrope NT may impair your thinking or reactions. Be careful while driving or doing an activity that requires you to be alert. Do not drink alcohol while you are taking Pyrope NT. It can increase the effects of alcohol, which could be dangerous. Grapefruit and grapefruit juice may also interact with this medicine and cause unwanted side effects. Avoid exposure to sunlight or tanning beds. Use of Pyrope NT can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.
Q. How often should I see the doctor ?
You may need to see your doctor regularly if you have started to take Pyrope NT. However, you must consult your doctor if the advised dosage of Pyrope NT does not improve your symptoms or you continue experiencing some unwanted side effects that affect your routine activities.
Q. Are there any special instructions regarding the storage and disposal of this medicine?
Keep your tablets in the pack until it is time to take them. Store them in a cool and dry place. Store them out of sight and reach of the children. Unused medications should be disposed of in special ways to ensure that pets, children and other people cannot consume them.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 14th Feb 2018.
The medicine details are for information purpose only. Consult a doctor before taking any medicine.
Manufacturer/Marketer Address
A – 504, Shapath-4, B/S Hotel Crowne Plaza, Opp. Karnavati Club, S. G. Highway ,Ahmedabad 380 051 Gujarat
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MRP
145.2
10 tablets in 1 strip
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