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MBA, MD Pharmacology
Last updated
22 Sep 2025 | 12:36 AM (IST)

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Pyrigesic Nano Gel

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Product introduction

Pyrigesic Nano Gel is a pain relieving medicine applied topically to relieve pain. It is used to treat pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve muscle pain, back pain, and other inflammatory conditions.

Pyrigesic Nano Gel is only meant for external use and should be used strictly as advised by your doctor. Rub a thin layer of the medicine into the affected areas with clean and dry hands. Avoid getting in contact with your eyes, nose, or mouth and avoid applying it on wounded or damaged skin. In case of accidental contact with these areas, you should rinse it with plenty of cold water.

Use of this medicine may cause few common side effects such as burning or stinging sensation, irritation, itching, and redness at the site of application in some people. Usually, the side effects will slowly go away as your body gets used to it. If they get worse or do not go away, you should let your doctor know.

Although medicines used on the skin are not normally affected by other medicines you should let your doctor know if you are taking any other medicine to be safe. You should also let your doctor know if you have any medical conditions or disorders to make sure it is safe. Ask your doctor for advice if you are pregnant or breastfeeding.


Uses of Pyrigesic Gel

Benefits of Pyrigesic Gel

In Pain relief

Pyrigesic Nano Gel gives fast relief from pain and swelling in conditions like rheumatoid arthritis, osteoarthritis and back pain by creating a cooling-warming effect. It works by causing the skin to feel cool and then warm. These feelings on the skin distract you from feeling the pain in your muscles and joints. Altogether, it will help you do your daily activities without much problem. Apply a thin layer of the medicine to the affected area no more than 3 to 4 times a day and rub in gently and thoroughly.

Side effects of Pyrigesic Gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pyrigesic

  • Application site reactions (burning, irritation, itching and redness)

How to use Pyrigesic Gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

How Pyrigesic Gel works

Pyrigesic Nano Gel is a combination of four medicines: Diclofenac, Linseed Oil, Menthol and Methyl Salicylate. Diclofenac and Methyl Salicylate are non-steroidal anti-inflammatory drugs (NSAIDs) which work by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Linseed Oil is a plant-based oil which further reduces inflammation and improves blood circulation at the site of application.It also increases the penetration of Diclofenac through the skin. Menthol produces a cooling effect on the skin.

Safety advice

Alcohol
No interaction found/established
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Pyrigesic Nano Gel during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Pyrigesic Nano Gel during breastfeeding is not available. Please consult your doctor.
Driving
No interaction found/established
Kidney
No interaction found/established
Liver
No interaction found/established

What if you forget to take Pyrigesic Gel?

If you miss a dose of Pyrigesic Nano Gel, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • You have been prescribed Pyrigesic Nano Gel to get relief from pain.
  • Apply 2-3 times daily or as prescribed by the doctor.
  • Do not apply to large areas of skin or near sensitive areas such as private parts or on broken or injured skin.
  • Avoid contact with the eyes, mouth, nose and rinse thoroughly in case of accidental contact or seek medical help in case of swallowing.
  • Avoid applying Pyrigesic Nano Gel right after bathing or shaving. Using this medication on freshly shaved skin areas can cause severe skin irritation.
  • Consult your doctor if you get excessive skin irritation or other unwanted effects.

Fact Box

Habit Forming
No
Therapeutic Class
DERMA

Patient concerns

I am having fever and cold since last two days
Dr. Sunil Sekhri
Diabetology
Tab Pyrigesic 500 1 SOS, Tab Loridin 1 Od x 3 days, Steam inhalation
Vomitings, nausea, dizziness,fever
Dr. Sunil Sekhri
Diabetology
Tab Pyrigesic 500 1 tab SOS, Tab Domstal 1 tab stat and gt yourself examined in clinic

FAQs

What is Pyrigesic Nano Gel used for?

Pyrigesic Nano Gel is used to relieve joint and muscle pain, reduce swelling, and ease inflammation. It is commonly used for backache, sprains, strains, tendon injuries, and conditions like arthritis or tennis elbow.

What precautions should I take while using Pyrigesic Nano Gel?

Avoid applying Pyrigesic Nano Gel to open wounds, eyes, mouth, or mucous membranes. Wash your hands thoroughly after application, and do not cover the area with tight bandages or apply heat unless advised by a doctor.

Who should not use Pyrigesic Nano Gel?

People should not use Pyrigesic Nano Gel if they are allergic to diclofenac, aspirin, or other NSAIDs. It is also not suitable for individuals who experience asthma attacks or skin reactions after using pain-relief medicines.

How should I apply Pyrigesic Nano Gel?

Apply Pyrigesic Nano Gel gently to the affected area three to four times a day. The amount depends on the size of the painful area. Do not apply it to open wounds or broken skin.

Is Pyrigesic Nano Gel safe for children?

Pyrigesic Nano Gel should not be used in children under 14 years of age. It is recommended only for adults and adolescents aged 14 and older.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Diclofenac diethylammonium. Brentford, Middlesex: GlaxoSmithKline Consumer Healthcare; 1997 [revised 24 Apr. 2017]. [Accessed 02 Apr. 2019] (online) Available from:External Link
  2. ScienceDirect. Linseed Oil. [Accessed 29 Apr. 2019] (online) Available from:External Link
  3. PubChem. Menthol. [Accessed 29 Apr. 2019] (online) Available from:External Link
  4. PubChem. Methyl salicylate. [Accessed 29 Apr. 2019] (online) Available from:External Link

Marketer details

Name: East India Pharmaceutical Works Ltd
Address: 6, NANDALAL BOSE SARANI,KOLKATA -700071
Country of origin: India

99.1
Inclusive of all taxes
MRP103.13  4% OFF
30.0 gm in 1 tube
SOLD OUT
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Available alternative with same salt composition
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Diclofenac (1.16% w/w) + Linseed Oil (3% w/w) + Menthol (5% w/w) + Methyl Salicylate (10% w/w)

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