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Pruf-P Tablet

Flupirtine (100mg)+ Paracetamol (325mg)

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Pruf-P Tablet is a pain relieving medicine. It is used to treat pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 07 Apr 2026 | 02:54 PM (IST)

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General Information

Contains

Flupirtine (100mg)+ Paracetamol (325mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Pruf-P Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, constipation, dryness in mouth, dizziness, headache, and sleepiness. If any of these side effects bother you or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.

Uses of Pruf-P Tablet

Pain relief

Benefits of Pruf-P Tablet

Pain relief
Pruf-P Tablet is used to treat pain associated with muscles, joints, cancer, dysmenorrhoea (severe abdominal pain during menstruation), tension headache and pain following orthopaedic surgery or injuries. It works by reducing substances in the body that cause pain. Take Pruf-P Tablet as prescribed by the doctor.

Side effects of Pruf-P Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pruf-P

Nausea
Vomiting
Constipation
Dryness in mouth
Dizziness
Headache
Sleepiness

How to use Pruf-P Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pruf-P Tablet should be taken with or after food.

How Pruf-P Tablet works

Pruf-P Tablet is a combination of two medicines: Flupirtine and Paracetamol, which relieves pain. Flupirtine is an analgesic (pain reliever) which works by blocking transmission of pain signals to the brain to lower pain perception. Paracetamol is an analgesic (pain reliever) and an anti-pyretic (fever reducer) which works by blocking the release of certain chemical messengers that cause fever and pain.

All substitutes for Pruf-P Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
Do not take indigestion remedies (antacids) within two hours of taking Pruf-P Tablet.
Do not take it with any other pain medicine without asking your doctor first.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Pruf-P Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Pruf-P Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Pruf-P Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Pruf-P Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Pruf-P Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Pruf-P Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
However, the use of Pruf-P Tablet is not recommended in patients with severe liver disease and active liver disease.

Frequently asked questions

Can I stop taking Pruf-P Tablet when my pain is relieved?

Pruf-P Tablet is usually used for short term and can be discontinued when your pain is relieved. However, Pruf-P Tablet should be continued if you are advised by your doctor to do so.

Can the use of Pruf-P Tablet cause damage to the liver?

Pruf-P Tablet contains Paracetamol, which is known to cause liver damage. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with underlying liver disease.

Can I take a higher than the recommended dose of Pruf-P Tablet?

No, taking a higher than the recommended dose of Pruf-P Tablet can lead to increased chances of side effects. If the recommended doses do not relieve your symptoms of if you experience increased severity of pain, please consult your doctor for re-evaluation.

What are the instructions for the storage and disposal of Pruf-P Tablet?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

References

User feedback

Patients taking Pruf-P Tablet

Twice A Day

58%

Once A Day

36%

Thrice A Day

Four Times A Day

What are you using Pruf-P Tablet for?

Pain relief

73%

Others

27%

How much was the improvement?

Average

44%

Excellent

33%

Poor

22%

What were the side-effects while using Pruf-P Tablet?

No Side Effect

50%

Nausea

25%

Dryness in mouth

25%

How do you take Pruf-P Tablet?

With food

83%

With or without food

17%

Please rate Pruf-P Tablet on price

Average

78%

Not Expensive

22%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Pruf-P Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

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Pruf-P Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Pruf-P Tablet

Benefits of Pruf-P Tablet

Side effects of Pruf-P Tablet

How to use Pruf-P Tablet

How Pruf-P Tablet works

All substitutes for Pruf-P Tablet

Ketoflam-P Tablet

Lupirtin-P Tablet

Flugesic-P Tablet

Vasfree P 100mg/325mg Tablet

Prasmol FP 100mg/325mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Can I stop taking Pruf-P Tablet when my pain is relieved?

Can the use of Pruf-P Tablet cause damage to the liver?

Can I take a higher than the recommended dose of Pruf-P Tablet?

What are the instructions for the storage and disposal of Pruf-P Tablet?

Fact Box

Habit Forming

Therapeutic Class

References

User feedback

Patients taking Pruf-P Tablet

What are you using Pruf-P Tablet for?

How much was the improvement?

What were the side-effects while using Pruf-P Tablet?

How do you take Pruf-P Tablet?

Please rate Pruf-P Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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