






Prothiaden M 50 Tablet
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 15 Apr 2026 | 11:58 AM (IST)
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General Information








Product introduction
Prothiaden M 50 Tablet may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of the treatment even if you feel better. It is important not to stop taking this medicine suddenly.
Some common side effects of this medicine include constipation, dry mouth, difficulty in urination, drowsiness, blurred vision, and increased heart rate. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.
You should avoid alcohol while taking Prothiaden M 50 Tablet, as it may worsen certain side effects. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Uses of Prothiaden M Tablet
Benefits of Prothiaden M Tablet
Prothiaden M 50 Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It reduces pain and associated symptoms such as mood changes, sleep problems, and tiredness. It also contains nutritional supplements that improve nerve conduction.
Side effects of Prothiaden M Tablet
- Constipation
- Weight gain
- Dryness in mouth
- Difficulty in urination
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Drowsiness
- Blurred vision
- Increased heart rate
How to use Prothiaden M Tablet
How Prothiaden M Tablet works
Quick tips
- Prothiaden M 50 Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
- Prothiaden M 50 Tablet may ease the pain within a few days but it may take 2-3 weeks before you see maximum benefit.
- Inform your doctor if you are taking any other pain-relieving medicines.
- Along with taking Prothiaden M 50 Tablet, your doctor might advise you to undergo physiotherapy to get relief from pain.
- Prothiaden M 50 Tablet might cause dry mouth. Frequent sips of water may help ease the discomfort.
- Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver
Frequently asked questions
Fact Box
Habit Forming
Therapeutic Class
References
- PubChem. Dothiepin. [Accessed 23 Apr. 2019] (online) Available from:
- MedlinePlus. Vitamin B-12. [Accessed 23 Apr. 2019] (online) Available from:
- Sciencedirect. Dosulepin. [Accessed 23 Apr. 2019] (online) Available from:
- Gupta JK, Sana QS. Potential Benefits of Methylcobalamin: A Review. Austin J Pharmacol Ther. 2015;3(3):1076. [Accessed 23 Apr. 2019] (online) Available from:
- Dosulepin Hydrochloride and methylcobalamin. Mumbai, Maharashtra: John Lee; [Accessed 15 Apr. 2026] (online). Available from:




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Marketer details
Address: 16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Vendor Details
A licensed vendor partner from your nearest location will deliver Prothiaden M 50 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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- Complete Hemogram (CBC & ESR)













