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Prothiaden M 50 Tablet is a combination of two medicines used to treat neuropathic pain. It works by protecting the nerve fibers against damage, repairing the damaged nerves. This way it effectively relieves the pain sensation and also elevates the mood.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 15 Apr 2026 | 11:58 AM (IST)
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Prothiaden M  50 Tablet image
Prothiaden M  50 Tablet image
Prothiaden M  50 Tablet image
Prothiaden M  50 Tablet image
Prothiaden M  50 Tablet image
Prothiaden M  50 Tablet image
Prothiaden M  50 Tablet image

Product introduction

Prothiaden M 50 Tablet may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of the treatment even if you feel better. It is important not to stop taking this medicine suddenly.

Some common side effects of this medicine include constipation, dry mouth, difficulty in urination, drowsiness, blurred vision, and increased heart rate. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.

You should avoid alcohol while taking Prothiaden M 50 Tablet, as it may worsen certain side effects. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.

Uses of Prothiaden M Tablet

Benefits of Prothiaden M Tablet

Neuropathic pain
Prothiaden M 50 Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It reduces pain and associated symptoms such as mood changes, sleep problems, and tiredness. It also contains nutritional supplements that improve nerve conduction.

Side effects of Prothiaden M Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Prothiaden M
  • Constipation
  • Weight gain
  • Dryness in mouth
  • Difficulty in urination
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Drowsiness
  • Blurred vision
  • Increased heart rate

How to use Prothiaden M Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prothiaden M 50 Tablet may be taken with or without food.

How Prothiaden M Tablet works

Prothiaden M 50 Tablet is a combination of two medicines:

Quick tips

  • Prothiaden M 50 Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
  • Prothiaden M 50 Tablet may ease the pain within a few days but it may take 2-3 weeks before you see maximum benefit.
  • Inform your doctor if you are taking any other pain-relieving medicines.
  • Along with taking Prothiaden M 50 Tablet, your doctor might advise you to undergo physiotherapy to get relief from pain.
  • Prothiaden M 50 Tablet might cause dry mouth. Frequent sips of water may help ease the discomfort.
  • Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Prothiaden M 50 Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Prothiaden M 50 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Prothiaden M 50 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Prothiaden M 50 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Prothiaden M 50 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Prothiaden M 50 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Prothiaden M 50 Tablet is used to treat neuropathic pain (nerve-related pain) and may also support mental health by improving mood.
Individual should not take Prothiaden M 50 Tablet if they are allergic to dosulepin, methylcobalamin, or any of its ingredients, have epilepsy (seizure disorder), severe liver problems, a recent heart attack, or are currently taking monoamine oxidase inhibitors (MAOIs, a type of antidepressant).
Prothiaden M 50 Tablet may increase the risk of abnormal heart rhythms, especially in elderly individuals or those with heart conditions. It can also lower the seizure threshold, increasing the risk of seizures. Use with caution if you have a history of suicidal thoughts, bipolar disorder, or alcohol abuse.
Serious side effects of Prothiaden M 50 Tablet include rapid or irregular heartbeat, chest pain, severe headache, confusion, yellowing of the skin or eyes (possible liver problem), thoughts of self-harm, persistent constipation or difficulty urinating, and allergic reactions such as swelling, rash, or trouble breathing. Seek immediate medical attention if you experience any of these symptoms.
Yes, Prothiaden M 50 Tablet may cause drowsiness, tiredness, and blurred vision, especially when starting treatment or increasing the dose. Avoid driving, operating machinery, or performing important tasks until you know how the medicine affects you.
Your doctor will determine the appropriate duration of Prothiaden M 50 Tablet based on your condition. Do not stop taking it suddenly, as abrupt withdrawal may cause mood changes, irritability, or other symptoms. Regular medical reviews are important during long-term use.

Fact Box

Habit Forming

No

Therapeutic Class

NEURO CNS
100% genuine products
100% genuine products
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Safe & secure payments
No contact delivery
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Fully sanitized facilities
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User feedback

Once A Day
98%
Alternate Day
1%
Thrice A Day
1%
Neuropathic pain
80%
Others
20%
Poor
67%
Average
33%
Dryness in mouth
100%
With food
100%
Average
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Abbott
Address: 16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Prothiaden M 50 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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