PRESTIFEN MR TABLET

Paracetamol (500mg)+ Chlormezanone (NA)+ Ibuprofen (NA)

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PRESTIFEN MR TABLET is a combination medicine used in the treatment of pain due to muscle spasm. It improves the movement of muscles and provides relief from pain and discomfort associated with muscle spasms.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 13 Jan 2026 | 09:25 PM (IST)

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General Information

Contains

Paracetamol (500mg)+ Chlormezanone (NA)+ Ibuprofen (NA)

Marketer

Synthiko Formulations & Pharma Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

PRESTIFEN MR TABLET may be prescribed alone or in combination with another medicine. It can be taken with or without food. You should take it strictly as advised by your doctor. Do not take more or use it for longer duration than recommended by your doctor.

Using of this medicine may cause few common side effects such as nausea, indigestion, stomach pain, weakness, dizziness, and sleepiness. If you experienced any such side effects that do not resolve with time or get worse, you should let your doctor know. Your doctor may help with ways to reduce or prevent them.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any medical conditions or disorders. Let your doctor also know all the other medicines you are taking. Pregnant and breastfeeding mothers should consult their doctors first before using the medicine.

Uses of Prestifen MR Tablet

Pain due to muscle spasm

Benefits of Prestifen MR Tablet

Pain due to muscle spasm
PRESTIFEN MR TABLET treats pain due to muscle spasm by relaxing stiff muscles. It also reduces swelling in the muscles. Altogether, it helps in easy movement and reduces discomfort. Once you see some improvement, you can start doing therapy exercises (such as walking or breathing exercises) that will help you get your strength back more quickly.
PRESTIFEN MR TABLET also does not cause much sleepiness due to the presence of Caffeine in it. As a result, you can do your daily activities more easily.

Side effects of Prestifen MR Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Prestifen MR

Nausea
Indigestion
Stomach pain
Weakness
Dizziness
Sleepiness
Heartburn

How to use Prestifen MR Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. PRESTIFEN MR TABLET may be taken with or without food.

How Prestifen MR Tablet works

PRESTIFEN MR TABLET is a combination of two pain relievers (Paracetamol, Ibuprofen) and a muscle relaxant (Chlormezanone). The pain relievers work by blocking the release of certain chemical messengers in the brain that cause pain and inflammation (redness and swelling). The muscle relaxant works on the centers in the brain and spinal cord to relieve muscle stiffness or spasm and improve movement of muscles.

Quick tips

You have been prescribed PRESTIFEN MR TABLET to get relief from pain and stiffness in the muscles.
It is better to take it with food or milk to prevent an upset stomach.
You may see results within 1.5 to 2 hours after taking PRESTIFEN MR TABLET. Take it exactly as advised by your doctor.
Avoid consuming alcohol while taking PRESTIFEN MR TABLET as it can increase your risk of stomach problems.
Inform your doctor if you have a history of seizures.
Along with taking PRESTIFEN MR TABLET, your doctor might advise you to undergo physiotherapy to get relief from muscle pain.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with PRESTIFEN MR TABLET

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of PRESTIFEN MR TABLET during pregnancy is not available. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

PRESTIFEN MR TABLET may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

CONSULT YOUR DOCTOR

It is not known whether PRESTIFEN MR TABLET alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

PRESTIFEN MR TABLET should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of PRESTIFEN MR TABLET is not recommended in patients with severe kidney disease. Long term use of this medicine can affect the kidney function.

Liver

CAUTION

PRESTIFEN MR TABLET should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of PRESTIFEN MR TABLET is not recommended in patients with severe liver disease.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

References

Roelofs PD, Deyo RA, Koes BW, et al. Non-steroidal anti-inflammatory drugs for low back pain. Cochrane Database Syst Rev. 2008 Jan 23;2008(1):CD000396. [Accessed 13 Jan. 2026]. Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Synthiko Formulations & Pharma Pvt Ltd
Address: 23, Vaibhav Industrial Estate. , Opp. ONIDA House, Mahakali Caves Road. , Andheri (E), Mumbai -400 093.

Vendor Details

Country of origin: India

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