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Pregem NT Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 06 Apr 2026 | 06:37 PM (IST)
Pregem NT Tablet is a combination medicine used for the treatment of neuropathic pain. This medicine decreases the pain by stopping the movement of pain signals to the brain.
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Pregem NT Tablet is currently sold out
Same composition alternative:
Nortryptomer-P 10mg/75mg Tablet
₹263₹285.23
Available alternative from Dr Reddy's
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Pregem NT Tablet
Pregem NT Tablet
strip of 10 tablets
₹124
₹140.63
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Same composition
Nortryptomer-P 10mg/75mg Tablet
Nortryptomer-P 10mg/75mg Tablet
strip of 10 tablets
Pregabalin (75mg) + Nortriptyline (10mg)
by Dr Reddy's Laboratories Ltd
Get by 6pm
₹263
₹22.4 per tablet

₹224

order for
₹1200

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General Information

Contains

Pregabalin (75mg)+ Nortriptyline (10mg)

Marketer

Gemith Pharma Pvt Ltd

Storage

Store below 25°C
The content is shown in English
Pregem NT Tablet image
Pregem NT Tablet image
Pregem NT Tablet image

Product introduction

Pregem NT Tablet may be taken with or without food, preferably at bedtime. Take it at the same time each day as this helps to maintain a consistent level of medicine in the blood. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the complete course of treatment even if you feel better. Do not stop this medication suddenly without talking to the doctor.


Some common side effects of this medicine include constipation, nausea, vision disturbance, and excessive sweating. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain, and to control it, you should exercise regularly and have a balanced diet. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.


Before taking Pregem NT Tablet, let your doctor know if you suffer from kidney or liver disease. Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses of Pregem NT Tablet

Benefits of Pregem NT Tablet

Treatment of Neuropathic pain
Pregem NT Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain.
Taking Pregem NT Tablet regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep taking the medicine until your doctor advises you to stop.

Side effects of Pregem NT Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pregem NT
  • Dryness in mouth
  • Dizziness
  • Sleepiness
  • Shakiness
  • Altered vision
  • Fast heart rate
  • Constipation
  • Nausea
  • Increased sweating
  • Weight gain
  • Nasal congestion (stuffy nose)
  • Aggressive behavior

How to use Pregem NT Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pregem NT Tablet may be taken with or without food.

How Pregem NT Tablet works

Pregem NT Tablet is a combination of two medicines: Pregabalin and Nortriptyline. Pregabalin is an alpha-2 delta ligand that decreases pain by modulating the calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant that increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves).

All substitutes for Pregem NT Tablet

For information purposes only. Consult a doctor before taking any medicine.

Nortryptomer-P 10mg/75mg Tablet

by Dr Reddy's Laboratories Ltd
₹26.3/tablet
112% costlier
<h3 class=bodySemiBold>Nortryptomer-P 10mg/75mg Tablet</h3>

Pregabid NT Tablet

by Intas Pharmaceuticals Ltd
₹24.67/tablet
99% costlier
<h3 class=bodySemiBold>Pregabid NT Tablet</h3>

PREgabA NT 75mg/10mg Tablet

by Torrent Pharmaceuticals Ltd
₹23.5/tablet
90% costlier
<h3 class=bodySemiBold>PREgabA NT 75mg/10mg Tablet</h3>

Pregadoc NT 75mg/10mg Tablet

by Lupin Ltd
₹26.2/tablet
111% costlier
<h3 class=bodySemiBold>Pregadoc NT 75mg/10mg Tablet</h3>

Nervite Tablet

by Macleods Pharmaceuticals Pvt Ltd
₹22.7/tablet
83% costlier
<h3 class=bodySemiBold>Nervite Tablet</h3>

Quick tips

  • Pregem NT Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
  • Inform your doctor if you are taking any other pain-relieving medicines.
  • Inform your doctor if you have a history of seizures.
  • Immediately seek medical help if you experience hallucinations, fever, sweating, shivering, fast heart rate, muscle twitching, or loss of coordination.
  • Along with taking Pregem NT Tablet, your doctor might advise you to undergo physiotherapy to get relief from pain.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Pregem NT Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Pregem NT Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

UNSAFE
Pregem NT Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Pregem NT Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
As Pregem NT Tablet may affect your alertness which may affect your ability to drive.
Kidney

Kidney

CAUTION
Pregem NT Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Pregem NT Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Pregem NT Tablet is a prescription medicine used to treat nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain. Thereby decreasing the pain sensation.
No, you should not stop taking Pregem NT Tablet even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Pregem NT Tablet, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain, and sweating. You may need to gradually taper the dose before you stop the medication completely.
Pregem NT Tablet can make you feel hungry, which might make you eat more, thereby increasing your chances of putting on weight.. However, preventing weight gain is easier than losing increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). DO not eat foods that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables, and low-calorie foods. Regular exercise will prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
Yes, Pregem NT Tablet may make you feel drowsy, or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights, or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while taking this medicine.
If you forget to take the scheduled dose of Pregem NT Tablet, and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects due to overdosage. If you are not sure what to do, consult your doctor about how to manage a situation like this.
No, taking a higher-than-recommended dose may not be more effective; rather, it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Pregem NT Tablet may impair your thinking or reactions. Be careful while driving or doing an activity that requires you to be alert. Do not drink alcohol while you are taking Pregem NT Tablet. It can increase the effects of alcohol, which could be dangerous. Grapefruit and grapefruit juice may also interact with this medicine and cause unwanted side effects. Avoid exposure to sunlight or tanning beds. Use of Pregem NT Tablet can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.
You may need to see your doctor regularly if you have started to take Pregem NT Tablet. However, you must consult your doctor if the advised dosage of Pregem NT Tablet does not improve your symptoms or if you continue experiencing some unwanted side effects that affect your routine activities. Pregem NT Tablet can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.

Fact Box

Habit Forming

No

Therapeutic Class

NEURO CNS

References

  1. Pregabalin [Prescribing Information]. Vega Baja, Puerto Rico: Pfizer Pharmaceuticals LLC; 2009. [Accessed 22 Apr. 2019] (online) Available from:
  2. Pregabalin [Prescribing Information]. New York, NY: Pfizer; 2011. [Accessed 22 Apr. 2019] (online) Available from:
  3. Pregabalin and Nortriptyline [Product Information]. Ahmedabad, Gujarat: La Renon Healthcare Limited. [Accessed 28th Sept. 2023] (online) Available from:
  4. Pregabalin+Nortriptyline [Prescribing Information]. Mumbai, Maharashtra: Alkem Laboratories Limited. [Accessed 28th Sept. 2023] (online) Available from:
  5. Nortriptyline [Prescribing Information]. Middlesex, London: Brown & Burk UK Ltd. 2025 [Accessed 14 Apr. 2025] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Gemith Pharma Pvt Ltd
Address: 228/A, Talpukur, Baghajatin Kolkata Kolkata WB 700086 IN

Vendor Details

Country of origin: India

Lab tests offered by us

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