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Pregastar Plus SR 75 Tablet is a medicine used in the treatment of neuropathic pain. It helps to decrease pain by controlling calcium channel activity of the nerve cells. It also provides essential nutrients to the body.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 08 May 2026 | 05:15 PM (IST)
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15 tablet sr
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Pregastar Plus SR 75 Tablet image
Pregastar Plus SR 75 Tablet image
Pregastar Plus SR 75 Tablet image
Pregastar Plus SR 75 Tablet image

Product introduction

Pregastar Plus SR 75 Tablet can be taken with or without food. The dose and duration will depend on what you are using it for and how well it helps your symptoms. Use it regularly and do not discontinue using it until the doctor tells you it is alright to stop.

The most common side effects of this medicine include dizziness, headache, sleepiness, and tiredness. If you experience any side effects that does not go away or worsen, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. In general, you should try to use the smallest amount necessary to control your symptoms.

Before using the medicine, you should tell your doctor if you have any other illnesses or disorders. It may also affect, or be affected by, some other medicines you are using so let your doctor know all the other medicines you are taking. Do not consume alcohol when on treatment with this medicine as it may cause excessive sleepiness. Pregnant and breastfeeding women should consult their doctors first before using the medicine.

Uses of Pregastar Plus Tablet SR

Benefits of Pregastar Plus Tablet SR

Neuropathic pain
Pregastar Plus SR 75 Tablet is used in neuropathic pain to support nerve health and reduce discomfort. It may help ease nerve inflammation, while Vitamin D3 supports nerve function and may improve symptoms like tingling, burning, or numbness.

Side effects of Pregastar Plus Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pregastar Plus
  • Dizziness
  • Sleepiness
  • Tiredness
  • Uncoordinated body movements

How to use Pregastar Plus Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pregastar Plus SR 75 Tablet may be taken with or without food.

How Pregastar Plus Tablet SR works

Pregastar Plus SR 75 Tablet is a combination of four medicines: Pregabalin, Methylcobalamin, Vitamin B6 (Pyridoxine) and Folic Acid. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Methylcobalamin and Vitamin B6 (Pyridoxine) are forms of vitamin B which help in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Folic Acid is also a form of vitamin B which provides essential nutrients to the nerves. Together, they relieve neuropathic pain (pain from damaged nerves).

All substitutes for Pregastar Plus SR 75 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Pregastar Plus SR 75 Tablet helps in treating and preventing nerve pain.
  • Its side effects are usually mild and temporary.
  • It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • To lower the chances of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Avoid consuming alcohol when taking Pregastar Plus SR 75 Tablet, as it may cause excessive sleepiness.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression or suicidal thoughts or behavior.
  • Do not stop taking the medication suddenly without talking to your doctor.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Pregastar Plus SR 75 Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Pregastar Plus SR 75 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Pregastar Plus SR 75 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Pregastar Plus SR 75 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Pregastar Plus SR 75 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Pregastar Plus SR 75 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Pregastar Plus SR 75 Tablet is primarily used to treat neuropathic pain, which is nerve pain often associated with conditions like diabetes, shingles, or nerve injury. It may also be prescribed to support nerve health in various neuropathic disorders.
Take Pregastar Plus SR 75 Tablet exactly as prescribed, usually once or twice daily. You may take it with or without food, but taking it with food may reduce stomach upset. Swallow Pregastar Plus SR 75 Tablet whole with water. Do not skip doses, and finish the course as advised by your doctor.
Before using Pregastar Plus SR 75 Tablet, inform your doctor about any allergies, kidney or liver disease, pregnancy, or breastfeeding. Use caution if you have a history of depression, seizures, or alcohol/substance use, as pregabalin can sometimes affect mood or cause drowsiness. Let your doctor know about any other medications you use.
Individuals should not take Pregastar Plus SR 75 Tablet if they are allergic to any of its ingredients. It is also contraindicated in people with end-stage kidney disease needing dialysis or those with a known allergy to similar drugs.
Seek immediate medical help if you notice serious side effects of Pregastar Plus SR 75 Tablet, such as severe allergic reactions (rash, itching, swelling, trouble breathing), mood changes, severe drowsiness, or unsteady movements. Contact your doctor if these occur.

Fact Box

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Therapeutic Class

NEURO CNS
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User feedback

Neuropathic pain
100%
Excellent
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Average
33%
Uncoordinated body movements
100%
With or without food
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Pregastar Plus SR 75 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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