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Powergesic MR Tablet is a combination medicine used in the treatment of pain due to muscle spasms. It improves the movement of muscles and provides relief from pain and discomfort associated with muscle spasms.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 16 Mar 2026 | 04:08 PM (IST)
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Powergesic MR Tablet
Powergesic MR Tablet
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General Information

Contains

Chlorzoxazone (500mg)+ Diclofenac (50mg)+ Paracetamol (325mg)

Marketer

Jenburkt Pharmaceuticals Ltd

Storage

Store below 25°C
The content is shown in English
Powergesic MR Tablet image
Powergesic MR Tablet image
Powergesic MR Tablet image
Powergesic MR Tablet image
Powergesic MR Tablet image
Powergesic MR Tablet image
Powergesic MR Tablet image

Product introduction

Powergesic MR Tablet can be taken with or without food. Take it in the dose and duration advised by your doctor. Do not take more or use it for a longer duration than recommended by your doctor.


Common side effects of Powergesic MR Tablet include nausea, dizziness, and stomach pain. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help with ways to reduce or prevent these side effects.


The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, or liver. To make sure it is safe for you, let your doctor also know about all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using the medicine.

Uses of Powergesic Tablet

  • Treatment of Pain due to muscle spasm

Benefits of Powergesic Tablet

Treatment of Pain due to muscle spasm
Powergesic MR Tablet is a combination medicine that is used to relieve pain, inflammation, and swelling in conditions that affect muscles. Also, it effectively relieves muscle stiffness or spasm, thereby improving muscle movement. It works by blocking chemical messengers in the brain that tell us we have pain.

Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Powergesic Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Powergesic
  • Dizziness
  • Constipation
  • Abdominal pain
  • Indigestion
  • Nausea

How to use Powergesic Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Powergesic MR Tablet may be taken with or without food.

How Powergesic Tablet works

Powergesic MR Tablet is a combination of a muscle relaxant (Chlorzoxazone) and two pain-relieving medicines (Diclofenac and Paracetamol). The muscle relaxant works on the centers in the brain and spinal cord to relieve muscle stiffness or spasms, thereby improving the movement of muscles. The pain-relieving medicines work by blocking the release of certain chemical messengers in the brain that cause pain and inflammation (redness and swelling).

All substitutes for Powergesic MR Tablet

For information purposes only. Consult a doctor before taking any medicine.

Cip-Zox Tablet

by Cipla Ltd
₹11.4/tablet
44% cheaper
<h3 class=bodySemiBold>Cip-Zox Tablet</h3>

Cip-Zox Tablet

by Cipla Ltd
₹13.85/tablet
31% cheaper
<h3 class=bodySemiBold>Cip-Zox Tablet</h3>

Mobizox Tablet

by Sun Pharmaceutical Industries Ltd
₹23.7/tablet
17% costlier
<h3 class=bodySemiBold>Mobizox Tablet</h3>

Myospaz Forte Tablet

by Win-Medicare Pvt Ltd
₹35.2/tablet
74% costlier
<h3 class=bodySemiBold>Myospaz Forte Tablet</h3>

Orthodex MR Tablet

by Psychotropics India Ltd
₹12.3/tablet
39% cheaper
<h3 class=bodySemiBold>Orthodex MR Tablet</h3>

Quick tips

  • Powergesic MR Tablet is most effective when taken along with proper rest and physical therapy.
  • Avoid consuming alcohol when taking Powergesic MR Tablet, as it may cause excessive drowsiness and increase the risk of liver damage.
  • Older adults may have increased drowsiness, confusion, and a higher risk of falling as a result of taking Powergesic MR Tablet.
  • Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough and cold) without asking your doctor first.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Powergesic MR Tablet.
Pregnancy

Pregnancy

UNSAFE
Powergesic MR Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Powergesic MR Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Powergesic MR Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Powergesic MR Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
Powergesic MR Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Powergesic MR Tablet is a combination of three medicines: diclofenac, paracetamol, and chlorzoxazone. This medication helps relieve muscle pain. Chlorzoxazone is a muscle relaxant that works by acting on the central nervous system. Diclofenac and paracetamol work by lowering the chemical substance (prostaglandins) in the body that causes pain and inflammation.
Powergesic MR Tablet should be continued if advised for a specific time duration by your doctor. However, it can be discontinued if you are using it for short-term pain relief.
Yes, the use of Powergesic MR Tablet can cause nausea and vomiting. In case you experience nausea while taking this medicine, take it with milk, food, or antacids. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small, frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark-colored, strong-smelling, and infrequent urination. Do not take any other medicine without speaking to your doctor.
Yes, the use of Powergesic MR Tablet can cause dizziness (feeling faint, weak, unsteady, or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.
Yes, the long-term use of Powergesic MR Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. The use of painkillers lowers the levels of prostaglandins in the body, leading to kidney damage on long-term use. The use of painkillers is not recommended for patients with underlying kidney disease.
No, taking a higher dose than the recommended dose of Powergesic MR Tablet can increase the risks of side effects. If you are experiencing increased severity of pain or if the pain is not relieved by the recommended doses, please consult your doctor for reevaluation.
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. Diclofenac [Prescribing Information]. Rouse Boulevard, Philadelphia: Iroko Pharmaceuticals; 1998 [revised Oct. 2013]. [Accessed 02 Apr. 2019] (online) Available from:
  2. Diclofenac [EMC Label]. Daventry, Northamptonshire: Dexcel Pharma Ltd.; 2017]. [Accessed 02 Apr. 2019] (online) Available from:
  3. ScienceDirect. Paracetamol. [Accessed 02 Apr. 2019] (online) Available from:
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User feedback

Twice A Day
52%
Once A Day
36%
Thrice A Day
12%
Muscle relaxation
52%
Others
15%
Pain relief
15%
Pain during menstruation
7%
Fever
7%
Excellent
53%
Average
33%
Poor
14%
Body ache
14%
Vomiting
10%
Sleepiness
10%
Dark colored urine
10%
Heartburn
10%
With food
80%
With or without food
20%
Average
52%
Expensive
29%
Not Expensive
20%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Jenburkt Pharmaceuticals Ltd
Address: Nirmala Apartments,93, Jayprakash Road, Andheri (West),Mumbai - 400 058. India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Powergesic MR Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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