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Polmeryl 2mg Tablet

Polmacoxib (2mg)
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Polmeryl 2mg Tablet is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat osteoarthritis of knee and hip joints. It inhibits the production of certain enzymes involved in inflammation, resulting in reduced inflammation, pain, and stiffness in the joints, and improves the function of joints.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 15 Jan 2026 | 09:39 AM (IST)
₹140 MRP ₹154.699% off 
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General Information

Contains

Polmacoxib (2mg)

Marketer

Medley Pharmaceuticals
The content is shown in English
Polmeryl 2mg Tablet image
Polmeryl 2mg Tablet image

Product introduction

Polmeryl 2mg Tablet should be taken with food to reduce the risk of an upset stomach. Take it in the dose and duration prescribed by your doctor. Also, continue taking this medicine for as long as your doctor prescribes it because if you stop taking the medicine abruptly, the symptoms may return.

Some common side effects of this medicine are headache, nausea, and upset stomach. These side effects are usually mild and go away on their own. However, if any of these symptoms get worse or bother you, consult with the doctor.

Do not take Polmeryl 2mg Tablet if you have a known history of allergic reactions to any of the ingredients of this medicine. Let your doctor know if you are taking, have recently taken, or might take any other medicines. To ensure that this medication is safe for you, also inform the doctor if you have any other pre-existing medical conditions. This medicine is contraindicated in pregnant and breastfeeding women as it can cause harm to the developing baby.

Uses of Polmeryl Tablet

  • Treatment of Osteoarthritis of knee and hip joints

Benefits of Polmeryl Tablet

Treatment of Osteoarthritis of knee and hip joints
Osteoarthritis is a chronic condition that causes pain, stiffness, and inflammation in the joints. Polmeryl 2mg Tablet provides quick relief from these symptoms of osteoarthritis. It also protects the gastrointestinal and cardiovascular systems. Hence, it is well-suited for patients who are at risk for gastrointestinal or cardiovascular side effects.

Side effects of Polmeryl Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Polmeryl
  • Headache
  • Nausea
  • Upset stomach

How to use Polmeryl Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Polmeryl 2mg Tablet should be taken with or after food.

How Polmeryl Tablet works

Polmeryl 2mg Tablet suppresses the production of proinflammatory substances (prostaglandins) by inhibiting certain enzymes involved in inflammation. This results in a reduction in inflammation-associated symptoms like pain, stiffness, or redness.

Quick tips

  • Drinking alcohol while taking Polmeryl 2mg Tablet may cause stomach bleeding.
  • You must inform your doctor if you have any history of cardiovascular/gastrointestinal diseases or renal/hepatic impairment, or are taking any painkiller medication.
  • You must consult with your doctor if you are planning a pregnancy or are breastfeeding.
  • Drinking alcohol while taking Polmeryl 2mg Tablet may cause stomach bleeding.
  • You must inform your doctor if you have any history of cardiovascular/gastrointestinal diseases or renal/hepatic impairment, or are taking any painkiller medication.
  • You must consult with your doctor if you are planning a pregnancy or are breastfeeding.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Polmeryl 2mg Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Polmeryl 2mg Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

UNSAFE
Polmeryl 2mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Polmeryl 2mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Polmeryl 2mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Polmeryl 2mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Frequently asked questions

Polmeryl 2mg Tablet is a nonsteroidal anti-inflammatory drug (NSAID) used to treat osteoarthritis of the knee and hip. It works by blocking certain enzymes that cause inflammation, helping to reduce pain, swelling, and stiffness, and improving joint movement.
Yes. Polmeryl 2mg Tablet contains polmacoxib, which is a selective COX‑2 NSAID, developed to reduce pain and swelling with the aim of fewer stomach and heart‑related side effects compared with some older NSAIDs like celecoxib or etoricoxib, though careful monitoring is still needed.​
Individuals should not take Polmeryl 2mg Tablet if they are allergic to polmacoxib or other NSAIDs, have active stomach or intestinal bleeding or ulcers, severe liver or kidney disease, uncontrolled high blood pressure, severe heart disease, or soon after heart bypass surgery. Your doctor will screen for these risks first.
Yes. Serious stomach or intestinal bleeding, ulcers, or holes can occur without warning during Polmeryl 2mg Tablet use. Stop the medicine and seek urgent care if you pass black stools, vomit blood, or have severe, persistent stomach pain.​
While on Polmeryl 2mg Tablet treatment, extra care is needed if older than 65 years, a smoker, drink alcohol regularly, have high blood pressure, high cholesterol, diabetes, fluid retention or swelling, asthma, inflammatory bowel disease, or a history of ulcers or GI bleeding.​
Yes. Polmeryl 2mg Tablet can cause fluid retention, raise blood pressure, worsen kidney function, and affect liver tests. Your doctor may monitor blood pressure, kidney function, and liver enzymes during treatment.
Serious side effects of Polmeryl 2mg Tablet include chest pain, sudden shortness of breath, weakness on one side, or slurred speech (possible heart attack or stroke), black stools, blood in vomit, or severe belly pain (GI bleeding/ulcer), swelling of face/lips/tongue, breathing trouble (severe allergy), etc. If you experience any of these symptoms, seek immediate medical attention.

Fact Box

Chemical Class

Stilbenes

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's -Selective COX-2 Inhibitors

References

  1. Intra Life Private Limited. Introducing POLIFORCE-2, the next-generation non-steroidal anti-inflammatory drug (NSAID) for osteoarthritis. [Accessed 27 Jul. 2023]. (online) Available from:
  2. La Renon. Polmacoxib [Product Label]. [Accessed 27 Jul. 2023]. (online) Available from:
  3. CrystalGenomics. Polmacoxib: Prescribing Information and warnings. [Accessed 27 Jul. 2023]. (online) Available from:
  4. La Renon: Polmacoxib [Product Information]. [Accessed 25 Jul. 2024] (online) Available from:
  5. Polmacoxib. Mysore, Bengaluru. Intra Life Pvt. Ltd.; [Accessed 11 Nov. 2025]. (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Medley Pharmaceuticals
Address: Plot No. D2 Medley House,Street No. 6 M.I.D.C. Area, Andheri (East), Mumbai-400 093, INDIA

Vendor Details

Country of origin: India

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