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Piptashil Capsule

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 25 Nov 2025 | 03:07 PM (IST)
Piptashil Capsule is a prescription medicine used in the treatment of nausea or vomiting experienced as a side effect of chemotherapy or anti-cancer treatment. It inhibits the signal to reach the brain that causes the feeling of nausea or vomiting.
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General Information

Contains

Aprepitant (125mg)+ Aprepitant (80mg)

Marketer

Shilpa Medicare Ltd

Storage

Store below 30°C
The content is shown in English
Piptashil Capsule image
Piptashil Capsule image
Piptashil Capsule image

Product introduction

Piptashil Capsule is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are constipation, indigestion, headache, tiredness, loss of appetite, and hiccups. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine can cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Piptashil Kit

  • Nausea and vomiting due to chemotherapy

Benefits of Piptashil Kit

Nausea and vomiting due to chemotherapy
Piptashil Capsule blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused due to some medicines or cancer treatment. This medicine helps you recover more comfortably from cancer treatments such as radiation therapy or chemotherapy. It is also effective at preventing nausea and vomiting after an operation (in adults only). Take it as prescribed by the doctor to get maximum benefit.

Side effects of Piptashil Kit

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Piptashil
  • Constipation
  • Indigestion
  • Headache
  • Tiredness
  • Loss of appetite
  • Hiccup
  • Increased liver enzymes

How to use Piptashil Kit

Take this medicine in the dose and duration as advised by your doctor. Check the label before use. Piptashil Capsule may be taken with or without food.

How Piptashil Kit works

Piptashil Capsule is a combination of two different doses of Aprepitant. It works by blocking the action of a chemical messenger in the brain that may cause nausea and vomiting during treatment with anti-cancer medicines.

All substitutes for Piptashil Capsule

For information purposes only. Consult a doctor before taking any medicine.

Apretero 125/80 Kit

by Hetero Drugs Ltd
₹1101/kit
13% cheaper
<h3 class=bodySemiBold>Apretero 125/80 Kit</h3>

Prepit Capsule

by Khandelwal Laboratories Pvt Ltd
₹1304/kit
3% costlier
<h3 class=bodySemiBold>Prepit Capsule</h3>

Fixpritant Kit

by RPG Life Sciences Ltd
₹1229/kit
3% cheaper
<h3 class=bodySemiBold>Fixpritant Kit</h3>

Quick tips

  • Piptashil Capsule is taken alongside other medicines to help stop sickness (nausea and vomiting) after chemotherapy.
  • Even if you do not feel like eating or drinking, try to sip water regularly to prevent you from becoming lacking in fluid in the body (dehydrated).
  • If you are taking any contraceptive 'pill' at the same time as this medicine, the effectiveness of the 'pill' can be reduced if you have a bout of being sick (vomiting) which lasts for more than 24 hours. In such a case, ask your doctor for additional contraceptive precautions.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Piptashil Capsule. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Piptashil Capsule during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Piptashil Capsule may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Piptashil Capsule may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

SAFE IF PRESCRIBED
Piptashil Capsule is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver

Liver

SAFE IF PRESCRIBED
Piptashil Capsule is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Frequently asked questions

Piptashil Capsule is a medicine used to prevent and treat nausea and vomiting caused by chemotherapy or other anti-cancer treatments. It works by blocking signals to the brain that trigger the feeling of nausea or vomiting.
Piptashil Capsule should not be taken by anyone allergic to aprepitant or any of the ingredients in the medicine. It must also not be used together with certain medicines such as pimozide, terfenadine, astemizole, or cisapride, because dangerous interactions may occur.
Before taking Piptashil Capsule, tell your doctor if you have liver problems, are taking blood thinners like warfarin, or use hormonal contraceptives. Aprepitant may make contraceptive pills less effective, so extra protection may be needed.
Yes. Piptashil Capsule is metabolised by the liver, so people with moderate to severe liver disease need extra monitoring. Signs of liver problems may include yellowing of the skin or eyes, dark urine, or unusual tiredness.
Serious side effects of Piptashil Capsule may include severe allergic reactions (such as swelling of the face, lips, or throat and difficulty breathing), skin reactions, or liver problems. If you notice these, you should seek medical help immediately.
Yes. Although they are rare, Piptashil Capsule can cause serious allergic reactions. Symptoms include rash, itching, hives, swelling, or difficulty breathing. Emergency treatment is needed if these occur.
Piptashil Capsule can affect blood-thinning medicines like warfarin and may change blood test results. While it does not usually affect heart rhythm, dangerous interactions can happen if taken with certain heart medicines.
Yes. Piptashil Capsule can reduce the effectiveness of birth control pills, patches, or implants. Women using hormonal contraception should use an extra non-hormonal method during treatment and for two months after the last dose of this medicine.

Fact Box

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

References

  1. Aprepitant. Whitehouse Station, New Jersey: Merch & Co, Inc.; 2006. [Accessed 15 Apr. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Shilpa Medicare Ltd
Address: 12-6-214/A1, Hyderabad Road, Raichur – 584 135, Karnataka, India.

Vendor Details

Country of origin: India

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