Pimareal Capsule is a medication used to treat hallucinations and delusions in people with Parkinson’s disease. It works by balancing serotonin activity in the brain to reduce these symptoms without making movement problems worse.
Take Pimareal Capsule at the same time each day with or without food, even if symptoms improve. Missing doses can reduce its benefits. Patients should follow their doctor’s instructions and report any side effects or concerns to ensure safe and effective treatment.
Common side effects of Pimareal Capsule include swelling in the hands, feet, or legs and a confusional state. Let your doctor know if any of these side effects persist or worsen. They can suggest ways to manage or treat them.
If you have dementia-related psychosis or heart problems, talk to your doctor before taking Pimareal Capsule for safety concerns. Antifungal drugs like ketoconazole may interact with Pimareal Capsule. Inform your doctor about all medications you are taking before starting Pimareal Capsule to avoid any potential risks. Pimareal Capsule cannot be used for the treatment of patients with dementia who experience psychosis unless their hallucinations and delusions are related to Parkinson’s disease.
In Treatment of hallucination and delusion associated with Parkinson's disease
Pimareal Capsule helps to treat Parkinson’s disease psychosis (PDP) by effectively reducing hallucinations and delusions without worsening motor symptoms. By improving the clarity of thought and reducing distressing experiences, Pimareal Capsule improves the quality of life for patients and daily functioning.
Side effects of Pimareal Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pimareal
Peripheral edema
Confusion
How to use Pimareal Capsule
Take this medicine in the dose and duration as advised by your doctor. Pimareal Capsule may be taken with or without food, but it is better to take it at a fixed time.
How Pimareal Capsule works
Pimareal Capsule works by modulating serotonin activity in the brain, specifically at 5-HT₂A receptors, which play a key role in hallucinations and delusions. It does not interfere with dopamine, the chemical essential for movement control. This allows Pimareal Capsule to effectively reduce hallucinations and delusions in people with Parkinson’s disease psychosis without worsening their motor symptoms.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pimareal Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Pimareal Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Pimareal Capsule is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Pimareal Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Pimareal Capsule is safe to use in patients with kidney disease. No dose adjustment of Pimareal Capsule is recommended.
Liver
SAFE IF PRESCRIBED
Pimareal Capsule is safe to use in patients with liver disease. No dose adjustment of Pimareal Capsule is recommended.
What if you forget to take Pimareal Capsule?
If you miss a dose of Pimareal Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Pimareal Capsule may affect heart rhythm, so patients with a history of heart conditions should have regular checkups.
Not everyone responds the same way to Pimareal Capsule. If symptoms persist or worsen, your doctor may adjust the dose or consider alternative treatments.
Maintain proper hydration and a healthy diet.
Fact Box
Chemical Class
Phenol ethers
Habit Forming
.
Therapeutic Class
NEURO CNS
Action Class
5-HT2A receptor inverse agonists
Patient concerns
Parkinson's disease tremors ,Insomnia.
Dr. Ravi Shankar M.
Ayurveda
Use Dhanadanayanadi kashayam 15ml twice a day with 15 ml water before food and Zandopa 10 grams twice a day witk milk after food and Tab Dhanvantari Vati 1-0-1 after food for 2 months
My mother suffering from Parkinson disease from 7 year , any affective medicine ?? Both hand and leg is shaking ,hardly stand up from bed himself, using parking tablet, syndopa plus and parkitidin
Dr. Saurav Arora
Homeopathy
Dear sir Parkinson's can only be managed with Homeopathy. There are few medicines which are used to improve quality of life and decrease disease progression
At times my fingers shiver when I hold cup, paper etc it's subconscious as in I do not notice it person Accompanying me notices I have no other health issues. Does this indicate Parkinson's disease? How is it diagnosed?
Is there have any medicine 4 PD Hi sir ,good afternoon My father is suffering from Parkinson's disease since last 3years. Recently he is taking syndopa plus revemer 3,Ropark 25 and amantrel I am not getting any positive results
Can Pimareal Capsule be taken with other medications?
Some medications, like antifungal drugs (e.g., ketoconazole), may interact with Pimareal Capsule. Always inform your doctor about all medications you are taking.
Is Pimareal Capsule a typical antipsychotic?
No, it is different from traditional antipsychotics because it does not block dopamine, making it safer for people with Parkinson’s.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not take two doses at once.
Can I stop taking Pimareal Capsule if my symptoms improve?
Do not stop taking Pimareal Capsule without consulting your doctor, as symptoms may return.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Pimavanserin [Prescribing Information]. San Diego, CA: Acadia Pharmaceuticals Inc.; 2018. [Accessed 12/02/2025] (online) Available from:
Pimavanserin [Patient Information]. San Diego, CA: ACADIA Pharmaceuticals Inc.; 2018. [Accessed 12/02/2025] (online) Available from:
Kitten AK, Hallowell SA, Saklad SR, Evoy KE. $name: a novel drug approved to treat Parkinson’s disease psychosis. Innovations in Clinical Neuroscience. 2018 Jan;15(1-2):16. (Online) Avaialble from:
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