Sign in to your account
or
By signing in you agree to our
Terms & conditions
 and 
Privacy policy

Pimavanserin

Written By Dr. Sakshi JainReviewed By Dr. Rajeev Sharma
Last updated 26 May 2025 | 10:04 AM (UTC)

Pimavanserin Uses

Pimavanserin is used in the treatment of Parkinson's disease.

How Pimavanserin works

Pimavanserin works by modulating serotonin activity in the brain, specifically at 5-HT₂A receptors, which play a key role in hallucinations and delusions. It does not interfere with dopamine, the chemical essential for movement control. This allows Pimavanserin to effectively reduce hallucinations and delusions in people with Parkinson’s disease psychosis without worsening their motor symptoms.

Common side effects of Pimavanserin

Peripheral edema, Confusion
Authenticity

Want to Know More

Read Our Editorial Policy

Expert advice for Pimavanserin

  • Pimavanserin may affect heart rhythm, so patients with a history of heart conditions should have regular checkups.
  • Not everyone responds the same way to Pimavanserin. If symptoms persist or worsen, your doctor may adjust the dose or consider alternative treatments.
  • Maintain proper hydration and a healthy diet.

Frequently asked questions for Pimavanserin

Some medications, like antifungal drugs (e.g., ketoconazole), may interact with Pimavanserin. Always inform your doctor about all medications you are taking.
No, it is different from traditional antipsychotics because it does not block dopamine, making it safer for people with Parkinson’s.
If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not take two doses at once.
Do not stop taking Pimavanserin without consulting your doctor, as symptoms may return.