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Pileum Suppository is a prescription medicine having a combination of medicines that is used to treat anal fissures. It provides relief from redness, swelling and itching. It decreases the pain sensation. It helps in softening the skin.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 04 Jan 2026 | 08:36 PM (IST)
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Pileum Suppository image
Pileum Suppository image
Pileum Suppository image
Pileum Suppository image

Product introduction

Pileum Suppository should be used in the dose and duration as advised by your doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. It is for external use only.

Do not use this medicine more than the recommended dose. Inform your doctor if you have known allergies from this medicine. The common side effects of this medicine include burning, irritation, itchiness, and redness at the application site.

If these side effects or any other symptoms which you think are because of this medicine persist for a longer duration, please consult your doctor. Inform your doctor if you are pregnant or are suffering from any other disease. This medicine is safe to use in breastfeeding mothers.

Uses of Pileum Suppository

Benefits of Pileum Suppository

Treatment of Anal fissure
Anal fissure is a small tear in the lining of the anus that may occur when you pass hard stools. Anal fissures typically cause pain while passing stools. Pileum Suppository decreases pain sensation at the affected area and helps in passing the stools easily. It also reduces swelling, redness, itching and irritation in the anal area. It soothes the area and gives relief from burning sensation. Apply Pileum Suppository as prescribed for faster healing. Make sure to avoid spicy, oil-rich food and take plenty of fibers to aid in digestion and thus prevent hard stools.

Side effects of Pileum Suppository

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pileum
  • Application site reactions (burning, irritation, itching and redness)

How to use Pileum Suppository

Remove the wrapper from the suppository before inserting it. Keep lying down for about 15 minutes after insertion so that the suppository does not come out before it melts.

How Pileum Suppository works

Pileum Suppository is a combination of four medicines: Hydrocortisone, Zinc Oxide, Lidocaine, and Allantoin, that helps treat anal fissures . Hydrocortisone is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Zinc Oxide has astringent and antiseptic action. Lidocaine is a local anesthetic which works by blocking pain signals from the nerves to the brain thereby decreasing pain sensation. Allantoin is a skin protectant that moisturizes and softens the skin.

All substitutes for Pileum Suppository

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Pileum Suppository is prescribed to get relief from pain and swelling in the rectal area due to fissures.
  • Do not take any other laxative along with Pileum Suppository without consulting your doctor.
  • Sometimes certain medicines like iron tablets, antibiotics might make your stools hard and difficult to pass. Inform your doctor if you are taking any of them.
  • Apart from using Pileum Suppository, you can indulge in warm baths. It may help soothe the area and thus may ease the pain.
  • Don't ignore the feeling of needing to pass stools. Some people suppress this feeling and put off going to the toilet until later. This may result in bigger and harder stools forming that are more difficult to pass later.
  • A fibre rich diet (wholegrain breads and cereals, fruit and green leafy vegetables) with six to eight full glasses of water each day and daily exercise are important in maintaining healthy bowel function.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Pileum Suppository during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Pileum Suppository may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

No interaction found/established
Kidney

Kidney

SAFE IF PRESCRIBED
Pileum Suppository is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver

Liver

SAFE IF PRESCRIBED
Pileum Suppository is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Frequently asked questions

Pileum Suppository is used to relieve swelling, pain, itching, and discomfort caused by hemorrhoids, anal fissures, and other minor rectal irritations. It helps reduce inflammation, soothe irritated skin, and promote healing.
Individuals should avoid Pileum Suppository if they are allergic to any of its ingredients, have viral, bacterial, or fungal infections in the rectal area, have tuberculosis, or have certain skin conditions around the anus.
Pileum Suppository is intended for short-term use to manage symptoms. Long-term or frequent use without medical advice may lead to skin thinning or irritation.
You should check with your doctor before using Pileum Suppository with other topical treatments to avoid irritation or reduced effectiveness.
You should wash and dry the affected area gently before applying Pileum Suppository, avoid contact with eyes or mouth, and use only the amount recommended by your doctor.
Although they are rare, allergic reactions such as severe itching, rash, swelling, or burning can occur with Pileum Suppository use. If these symptoms appear, stop using the cream and seek medical advice immediately.
If you have chronic skin conditions like eczema or psoriasis near the rectal area, consult your doctor before using Pileum Suppository to ensure it is safe for you.
Yes, Pileum Suppository provides rapid numbing of the affected area, often giving pain relief within minutes. Pileum Suppository also works on healing and reducing inflammation over time.

Fact Box

Habit Forming

No

Therapeutic Class

UROLOGY

References

  1. Hydrocortisone+Zinc Oxide+Lidocaine+Allantoin [Summary of Product Characteristics]. Thane, India: Kremoint Pharma Pvt. Ltd.; 2024.
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User feedback

Once A Day
93%
Twice A Day
7%
Anal fissure
81%
Others
12%
Excessive skin dryness
6%
Poor
53%
Average
27%
Excellent
20%
No Side Effect
67%
Application site reactions (burning, irritation, itching and redness)
33%
With or without food
67%
Empty stomach
33%
Average
67%
Not Expensive
33%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: MMC Healthcare Ltd
Address: 61, Kurinji Street, Fathima Nagar, Valasaravakkam, Chennai - 600087 / 113, Visalakshi Street, Devi Kurumariamman Nagar, Valasaravakkam, Chennai-600087

Vendor Details

Country of origin: India
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