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Picofen Syrup

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 09 Apr 2026 | 06:54 PM (IST)
Picofen Syrup is a combination medicine used to treat constipation. It works by drawing water into the bowel, softening stools, and making them easier to pass. It also helps relieve discomfort associated with gas.
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Cremaffin Plus Syrup Refreshing Sugar Free
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Picofen Syrup
Picofen Syrup
bottle of 100 ml Syrup
₹93.2
₹103.13
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Same composition
Cremaffin Plus  Syrup Refreshing Sugar Free
Cremaffin Plus Syrup Refreshing Sugar Free
bottle of 225 ml Syrup
by Abbott
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Picofen Syrup image
Picofen Syrup image

Product introduction

Take Picofen Syrup as advised by your doctor, with or without food. The dose may depend on the severity of your condition and response to treatment. Continue using it for the recommended duration for best results. Inform your doctor about all other medicines you are taking, as some may interact with this medicine.


Common side effects include nausea, diarrhea, abdominal cramps, and bloating. These are usually mild and temporary, but consult your doctor if they persist or worsen. Drinking plenty of fluids, eating a fiber-rich diet, and regular physical activity can help improve results.


Before taking Picofen Syrup, inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Also, let your doctor know if you have any underlying medical conditions so that the treatment can be used safely.

Uses of Picofen Syrup

Benefits of Picofen Syrup

Treatment of Constipation
Picofen Syrup is a laxative used to treat constipation (infrequent bowel movements and hard, dry stools). It works by drawing water into the bowels, making the stools softer and easier to pass. It also increases the movement of the intestines, which helps empty the bowels more easily. This helps reduce pain and discomfort and improves quality of life.

Side effects of Picofen Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Picofen
  • Diarrhea
  • Abdominal discomfort
  • Stomach pain

How to use Picofen Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Picofen Syrup may be taken with or without food.

How Picofen Syrup works

Picofen Syrup is a combination of three medicines: sodium picosulfate, liquid paraffin, and milk of magnesia. Sodium picosulfate is a stimulant laxative that increases peristalsis (the wave-like movement of the intestines) and helps push stools forward. Liquid paraffin is a lubricant laxative that helps retain water and fat in the stools, making them softer. Milk of magnesia is an osmotic laxative that draws water into the intestine through osmosis, which softens the stools. Together, these medicines make stools easier to pass.

Quick tips

  • An overdose of Picofen Syrup may also lead to dehydration. Drink plenty of water during the day to help soften stools and reduce the risk of dehydration.
  • Eat a fiber-rich diet (about 20–35 g/day), stay physically active, and follow a regular toilet routine to help prevent constipation.
  • Do not hold stools when you feel the urge, as delaying bowel movements can worsen constipation and make stools harder.
  • Plan to stay near a toilet after taking Picofen Syrup, as laxatives may stimulate bowel movements. Avoid long-distance travel since the medicine can cause stimulated bowel movements.
  • Avoid using Picofen Syrup for prolonged periods without medical advice, as it is usually intended for short-term relief of constipation.
  • Consult your doctor if constipation persists, if you need the medicine daily, or if symptoms do not improve.
  • Stop taking Picofen Syrup and seek medical advice if you develop severe abdominal pain, vomiting, or persistent diarrhea.
  • Seek urgent medical attention if you notice rectal bleeding or black stools.
  • Inform your doctor if you have a history of bowel obstruction, appendicitis, kidney disease, or other serious gastrointestinal conditions before using Picofen Syrup.
  • Consult your doctor if constipation is persistent, new, or associated with symptoms such as unexplained weight loss or fever.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Picofen Syrup. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Picofen Syrup during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Picofen Syrup may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Picofen Syrup may cause side effects that could affect your ability to drive.
Kidney

Kidney

CAUTION
Picofen Syrup should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

SAFE IF PRESCRIBED
Picofen Syrup is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Frequently asked questions

Picofen Syrup syrup is used to treat constipation and make bowel movements easier. It works by drawing water into the stool, which softens it and helps it pass more comfortably. It may also help relieve gas and abdominal discomfort associated with constipation. This medicine provides symptom relief but should be used only as advised by a doctor, especially if constipation is frequent. Drinking enough fluids and eating fiber-rich foods can also help improve bowel habits.
Picofen Syrup syrup should be taken in the dose and duration advised by your doctor. It can usually be taken with or without food, depending on what feels comfortable for your stomach. Follow the schedule recommended by your doctor and do not stop too early, as constipation may return. Drink plenty of water and maintain a fiber-rich diet to help the medicine work better. Consult your doctor if symptoms persist or worsen.
Picofen Syrup syrup may cause diarrhea, stomach discomfort, or abdominal cramps in some people. These side effects are usually mild and temporary as the body adjusts to the medicine. Occasionally, people may also experience bloating or loose stools. If diarrhea becomes severe, persistent, or is associated with dehydration or weakness, stop using the medicine and consult your doctor. Always use it only in the recommended dose and duration.
Picofen Syrup syrup helps relieve constipation by softening stools and improving bowel movement. It works through three actions: one ingredient stimulates the intestines to move stool forward, another draws water into the bowel to soften the stool, and another acts as a lubricant to help stool pass more easily. Together, these effects make bowel movements smoother and more comfortable. Relief usually occurs within several hours to a day, depending on the person.
It’s unsafe to take alcohol while taking Picofen Syrup. Alcohol can make the medicine work less effectively and may increase side effects like loose stools, dehydration, and dizziness. Since this medicine already helps your bowel movement, adding alcohol can make you lose too much fluid and feel weak or unwell. If you accidentally drink alcohol and notice symptoms like severe diarrhea, vomiting, or feeling very dizzy, contact your doctor.
Picofen Syrup syrup should be used only with a doctor’s advice in people who are pregnant, breastfeeding, or have kidney, liver, or heart problems. Extra caution is also needed if you are taking other medicines, as interactions may occur. It may not be suitable for everyone, especially if you have severe dehydration, bowel obstruction, ongoing stomach problems, or certain chronic illnesses. Always inform your doctor about your medical history and other medicines before using it.
Picofen Syrup should be stored exactly as directed on the label or by your doctor. The medicine may lose effectiveness if exposed to excessive heat, sunlight, or moisture. Keep it in a cool, dry place away from direct heat and light, and avoid storing it in very hot areas such as near a stove or inside a parked car. Always keep it out of reach of children and do not use it after the expiration date or if the color, smell, or texture changes unexpectedly.

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GASTRO INTESTINAL
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mediyork Pharma Pvt Ltd
Address: CF 261, 1st & 2nd Floor, Motor Market, Manimajra (Chandigarh) - 160101

Vendor Details

Country of origin: India
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