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Composition for PERINORM MPS

Metoclopramide(5 mg),Simethicone(125 mg)

food interaction for PERINORM MPS

alcohol interaction for PERINORM MPS

pregnancy interaction for PERINORM MPS

lactation interaction for PERINORM MPS

There is no data available. Please consult doctor before consuming the drug.
Perinorm mps 5 mg/125 mg tablet may cause excessive drowsiness and calmness with alcohol.
Perinorm mps 5 mg/125 mg tablet is probably safe to use during pregnancy.
Either animal studies have shown no adverse effect on the fetus, but there is no human studies or animal studies have shown an adverse effect that was not confirmed in human studies. Please consult your doctor.
Perinorm mps 5 mg/125 mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.


Metoclopramide(5 mg)


Metoclopramide speeds up the rate at which the stomach empties its contents into the intestines. It  is used for short-term treatment of heartburn caused by gastroesophageal reflux . Metoclopramide is also used to treat slow emptying of food from the stomach in people with diabetes (also called diabetic gastroparesis), which can cause nausea, vomiting, heartburn, loss of appetite, and a feeling of fullness after meals. It is used to prevent or treat nausea and vomiting associated with chemotherapy, radiotherapy or migraine.

How it works

Metoclopramide belongs to a class of drugs called anti-emetics that works against a chemical called dopamine secreted in intestine and brain. It works on a part of intestine and brain that controls vomiting sensations and speeds up  emptying of stomach.

Common side effects

Nausea, Diarrhoea, Frequent urge to urinate, Absence of menstrual periods, Breast enlargement, Decreased sexual function, Drowsiness, Fatigue, Dizziness, Headache
Simethicone(125 mg)


Simethicone is used to relieve painful pressure, hiccups, bloating and fullness caused by excess gas in the stomach and intestines in adults as well as in children.

How it works

Simethicone belongs to class of medications called surface active substances. It is an antifoaming agents and works by acting on inner lining of intestine and allowing gas bubbles to come together more easily helping to release trapped wind.

Common side effects

Allergic reaction


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Expert advice for PERINORM MPS

  • Take metoclopramide half an hour before your meals.
  • Consult a doctor immediately if you begin to have repetitive movements of the eyes, tongue, face, arm, or legs.
  • Do not take the medicine if you are allergic to it.
  • Do not take this drug if you are breast-feeding.
  • Do not o drive or operate heavy machinery after taking this drug as it can make you feel drowsy.
  • Avoid taking alcohol till you know how the drug affects your body.

Frequently asked questions for PERINORM MPS


Q. Is metoclopramide antacid, anticholinergic, antihistamine, steroid, antipsychotic or antibiotic?
Metoclopramide is not antacid, anticholinergic, antihistamine, steroid, antipsychotic or antibiotic. It is an antiemetic drug belonging to class of dopamine antagonists. 
Q. Is Metoclopramide/Reglan safe?
Metoclopramide/Reglan is a relatively safe drug if used in prescribed dose for prescribed duration as advised by your doctor.

Q. How long can I take it?
 Do not take it for more than 12 weeks.
Q. Are there any serious side-effects associated with metoclopramide?
Metoclopramide might cause side-effects like hallucinations, decreased consciousness, allergies, slowing of heartbeats, shaking, low blood pressure, or depression.
Q. Can I take metoclopramide with diazepam?
Metoclopramide may increase the sedative effect of diazepam. Consult your doctor before taking the drug if you are also taking cetrizine, digoxin, mevacuronium, levodopa or codeine.
Q. Is metoclopramide available over the counter?
No. Metoclopramide is not available as an over the counter (OTC) drug. It is dispensed only upon a valid prescription from a doctor.
Q. Does affect birth control?
There is no evidence of metoclopramide affecting birth control or contraception. Please consult your doctor to confirm whether you require a secondary birth control measure while taking the medicine.


Q. Is simethicone antacid?
No. Simethicone is not an antacid. But it is used in preparations which are used as antacid.

Q. Does it contain aspirin?
It does not contain aspirin.
Q. Is simethicone available over the counter?
Yes. Simethicone is sold over the counter without a prescription.
Q. Is simethicone gluten free?
Yes. Simethicone is gluten free. However, please refer to package insert of the prescribed brand before use.
Q. Is simethicone safe?
Yes. Simethicone is relatively safe.

Q. Is it safe for babies?
 Safe for infants and babies, if used as recommended. In case of any side-effects, consult your doctor.
Q. Is it safe to take simethicone daily?
It is advisable to take simethicone only as per the instructions of the doctor.
Q. Is simethicone good for gas?
Yes. Simethicone is effective in the treatment of gas.

Q. Does it have any side effects?
 It does not have any known serious side-effects.
Q. Can I take simethicone with ibuprofen, famotidine, lansoprazole, omeprazole, antibiotics, ranitidine, ciprofloxacin, Pepto-bismol, or Depakote?
Yes. Simethicone can be taken with ibuprofen, famotidine, lansoprazole, omeprazole, antibiotics, ranitidine, ciprofloxacin, Pepto-bismol (bismuth subsalicylate) or Depakote (divalproate sodium), if prescribed by your doctor.
Q. Does simethicone cause nausea or constipation?
Simethicone is not known to cause nausea or constipation. If you experience any such symptoms, please consult your doctor.
Q. Is simethicone effective against acid reflux?
Simethicone is effective in controlling acid reflux if combined with an antacid.


Content on this page was last updated on 01 November, 2015, by Dr. Varun Gupta (MD Pharmacology)