Peraflox MS Syrup

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 25 Nov 2025 | 03:07 PM (IST)

Peraflox MS Syrup is given to children for the treatment of bacterial infections of the teeth, lungs, gastrointestinal tract, urinary tract, and genital tract. This medicine is also given as an empirical antibiotic for infected diarrhea mixed with blood and serious infections like peritonitis.

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General Information

Contains

Ofloxacin (50mg)+ Metronidazole (125mg)+ Simethicone (2mg)

Marketer

Periodic Healthcare

Storage

Store below 30°C

The content is shown in English

Product introduction

Give Peraflox MS Syrup to your child orally, preferably at a fixed time, either before or after meals. In case your child develops a stomach upset, prefer giving it with meals. Generally, this medicine is prescribed to be given two times a day, in the morning and evening. If your child vomits within 30 minutes of intake, repeat the same dose but do not double the dose if it is time for the next dose. Never change the dose, time, and way prescribed by the doctor since these depend upon the type and severity of the infection, your child’s age, and body weight.

In some cases, this medicine may cause some minor and temporary side effects, including nausea, vomiting, weight loss, metallic taste, headache, loss of appetite, abdominal cramps, and mild skin rash. These side effects are temporary and recede when your child gets used to the medicine. In case the side effects persist or start bothering your child, consult your child’s doctor without any delay.

Narrate your child’s complete medical history to your child’s doctor, including any previous episode of allergy, heart problem, liver impairment, and kidney malfunction. This information is critical for dose alterations and for planning your child’s overall treatment.

Uses of Peraflox MS Syrup

Treatment of Bacterial infections

Benefits of Peraflox MS Syrup

Treatment of Bacterial infections
Peraflox MS Syrup is an antibiotic medicine given to children for the treatment of a wide range of bacterial infections such as tooth abscess, gum infection, pneumonia, diarrhea, dysentery, peritonitis, burning sensation while passing urine, and certain genital tract infections. This medicine inhibits the growth of infection-causing bacteria by stopping it from multiplying. You may start seeing an improvement in the infection within 3 to 5 days of regular dosing. But, you must still finish the full course of the medicine and never stop it abruptly by yourself as that may worsen your child’s condition or cause infection recurrence.

Side effects of Peraflox MS Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Peraflox MS

Vomiting
Nausea
Weight loss
Abdominal pain
Headache
Diarrhea
Loss of appetite
Dizziness
Insomnia (difficulty in sleeping)
Metallic taste
Urine discoloration

How to use Peraflox MS Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Peraflox MS Syrup may be taken with or without food.

How Peraflox MS Syrup works

Peraflox MS Syrup is a combination of three active ingredients. While two of its ingredients, namely ofloxacin and metronidazole are antibiotics, simethicone is a gas-absorbing agent that improves gastric tolerability of the combination. The antibiotic ingredients interfere with the genetic material of bacteria by impairing its DNA. This kills the infection-causing bacteria, preventing its growth and stopping the infection. On the other hand, Simethicone binds with the gas bubbles produced as a result of the other two ingredients or as a result of some other problem. By doing so, it aids in the removal of gases and provides relief in stomach pain and bloating.

Quick tips

Diarrhea is a common side effect of this medicine. If it occurs, make sure your child drinks plenty of water.
Your child may have an altered taste or furry tongue (coating of Peraflox MS Syrup on tongue) after taking Peraflox MS Syrup. Eating citrus fruit or sipping plenty of water or fruit juice may help.
Do not give any calcium, magnesium, iron, vitamin, or antacid within 2 hours of taking Peraflox MS Syrup as these can affect the absorption of the medicine.
Never use this medicine for the common cold and flu as they are caused by viruses and Peraflox MS Syrup treats only bacterial infections.
Discontinue Peraflox MS Syrup and inform the doctor immediately if your child develops a rash, itchy skin, swelling of face and mouth, or has difficulty in breathing.
Only give Peraflox MS Syrup to your child for their current infection. Never save medicine for future illnesses.

Safety advice

Alcohol

UNSAFE

Consumption of alcohol with Peraflox MS Syrup may cause a disulfiram-like reaction, leading to symptoms such as flushing, increased heart rate, low blood pressure, nausea, lightheadedness, and severe headache.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Peraflox MS Syrup during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Peraflox MS Syrup may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Peraflox MS Syrup may cause side effects that could affect your ability to drive.
Peraflox MS Syrup may make you feel sleepy, dizzy, confused. You may have hallucinations, fits (convulsions) or temporary eyesight problems (such as blurred or double vision) affecting your ability to drive.

Kidney

CAUTION

Peraflox MS Syrup should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Peraflox MS Syrup should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Frequently asked questions

What should I tell the doctor before giving Peraflox MS Syrup to my child?

You must tell the doctor if your child is suffering from heart disease, seizures, psychiatric disorders, diabetes, photoallergy (allergy from sunlight), neuromuscular disorders, rheumatoid arthritis, or genetic disorders involving blood vessels. This is because there is a possibility that Peraflox MS Syrup may aggravate these conditions and result in complications.

Can Peraflox MS Syrup be given along with cough and cold medicines?

No, do not give Peraflox MS Syrup with cough and cold medicines. The reason being, one of the ingredients present in Peraflox MS Syrup can interact with alcohol-containing medicines like cough syrups and can lead to disulfiram reaction, causing nausea, vomiting, flushing, dizziness, etc.

What if I give an overdose of Peraflox MS Syrup by mistake?

An extra dose of Peraflox MS Syrup is unlikely to harm. However, if you think you have given too much to your child, immediately speak to a doctor. Overdose may cause unwanted side effects such as seizures, tremors, severe headache, sudden weakness, blood cell abnormalities, and rapid and irregular heartbeat. Rush to your child’s doctor if you notice any of these symptoms.

What should I do if my child shows no improvement even after taking Peraflox MS Syrup for the prescribed duration?

It could mean that Peraflox MS Syrup is unable to kill the infection-causing bacteria. In such a case, visit your child’s doctor who may prescribe some other antibiotic that has a higher efficacy against the disease-causing bacteria. Remember, that sometimes, such antibiotics may have to be given by IV route (intravenous injection) in the hospital.

Can other medicines be given at the same time as Peraflox MS Syrup?

Peraflox MS Syrup can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Peraflox MS Syrup. Also, check with your child’s doctor before giving any medicine to your child.

How should Peraflox MS Syrup be stored?

Store Peraflox MS Syrup at room temperature, in a dry place, away from direct heat and light. Children may accidentally consume medicines if they find them while playing around. So, make sure that all the medicines are kept away from their reach and sight.

Can I get my child vaccinated while on treatment with Peraflox MS Syrup?

Antibiotics usually do not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, children taking antibiotics should not get vaccinated until they recover from the illness. As soon as your child feels better, the vaccine can be given.

My child has been passing red-brown urine ever since he started taking Peraflox MS Syrup? Is it normal?

Peraflox MS Syrup contains active ingredient metronidazole, which causes red-brown urine. It is not pathogenic but a side effect. It subsides once the medicine is stopped after the completion of the treatment.

Fact Box

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Periodic Healthcare
Address: Plot 97, Industrial Area, Phase 1 Panchkula, Haryana, India Pincode: 134113

Vendor Details

Country of origin: India

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