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Parofi Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 02 Mar 2026 | 12:39 PM (IST)
Parofi Tablet is a pain relieving medicine. It is used to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.
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General Information

Contains

Rofecoxib (25mg)+ Paracetamol (500mg)

Marketer

Lupin Ltd

Storage

Store below 30°C
The content is shown in English
Parofi Tablet image
Parofi Tablet image

Product introduction

Parofi Tablet can be taken with or without food. You should take it regularly as advised by your doctor. Your doctor may change the dose and time between doses according to your pain level and your needs. Do not take more or use it for longer duration than recommended by your doctor.

Some of the common side effects of this medicine include diarrhea, stomach pain, indigestion, flatulence, swelling of hands and feet, and flu-like symptoms. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help with ways to reduce or prevent these side effects by prescribing an alternative medicine or adjusting the dose.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, liver, or have stomach ulcers. To make sure it is safe for you, let your doctor know about all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using this medicine.

Uses of Parofi Tablet

Benefits of Parofi Tablet

Pain relief
Parofi Tablet is used to relieve pain and inflammation associated with conditions like arthritis, muscle injuries, and other painful disorders. It helps reduce discomfort, improve mobility, and support daily functioning by targeting both pain and swelling effectively.

Side effects of Parofi Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Parofi
  • Diarrhea
  • Stomach pain
  • Indigestion
  • Flatulence
  • Swelling of hands
  • Feet swelling
  • Flu-like symptoms

How to use Parofi Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Parofi Tablet may be taken with or without food.

How Parofi Tablet works

Parofi Tablet is a combination of two medicines: Rofecoxib and Paracetamol. Rofecoxib is a non-steroidal anti-inflammatory drug (NSAID) and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers in the brain that cause pain and fever.

Quick tips

  • Parofi Tablet is used to treat various painful conditions.
  • It is better to take it with milk or food to prevent stomach upset.
  • Do not take it with any other pain medicine without asking your doctor first.
  • Regularly monitor your blood pressure while taking this medicine, particularly in the first two weeks after starting treatment.
  • During long-term treatment, your doctor may want to take regular blood tests to monitor your liver function.
  • Inform your doctor if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease.
  • Parofi Tablet is used to treat various painful conditions.
  • It is better to take it with milk or food to prevent stomach upset.
  • Do not take it with any other pain medicine without asking your doctor first.
  • Regularly monitor your blood pressure while taking this medicine, particularly in the first two weeks after starting treatment.
  • During long-term treatment, your doctor may want to take regular blood tests to monitor your liver function.
  • Inform your doctor if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Parofi Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

UNSAFE
Parofi Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Parofi Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CAUTION
Parofi Tablet may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Parofi Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
However, Parofi Tablet contains paracetamol which is considered the safest painkiller for kidney disease patients.
Liver

Liver

UNSAFE
Parofi Tablet is unsafe to use in patients with liver disease and should be avoided.
However, the use of Parofi Tablet is not recommended in patients with severe liver disease and active liver disease.

Frequently asked questions

Parofi Tablet should be continued as advised by your doctor if you are using the medicine for a condition associated with long-term pain. It can be discontinued if you are using it for short-term pain relief.
Yes, the use of Parofi Tablet may cause nausea. Eat smaller, more frequent meals to reduce the feeling of nausea. Avoid food that is salty, spicy, fried, or fatty.
No, Parofi Tablet should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.
Yes, Parofi Tablet is a pain killer and prescription medicine that is used to relieve signs and symptoms of arthritis, and acute pain in adults.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. Rofecoxib. Whitehouse Station, New Jersey: Merck & Co., Inc.; 1998. [Accessed 02 Apr. 2019] (online) Available from:
  2. ScienceDirect. Rofecoxib. [Accessed 02 Apr. 2019] (online) Available from:
  3. ScienceDirect. Paracetamol. [Accessed 02 Apr. 2019] (online) Available from:
  4. ScienceDirect. Rofecoxib. [Accessed 02 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Vendor Details

Country of origin: India

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