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Parexel Plus 5mg/2.5mg Tablet

Prescription Required

Product introduction

Parexel Plus 5mg/2.5mg Tablet is used to treat irritable bowel syndrome (symptoms include abdominal pain, cramping, bloating, and diarrhea or constipation). It prevents the sudden spasm of muscles to relieve stomach pain and cramps. It also promotes easy passage of gas to reduce stomach discomfort.

Parexel Plus 5mg/2.5mg Tablet is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are nausea, constipation, memory impairment, blurred vision, dryness in the mouth, difficulty in urination, and coordination impairment. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.
Lifestyle modifications like having a fiber-rich diet, avoiding foods that trigger your symptoms, increasing fluid intake, and regular exercise can help you to get better results. Before taking it, you should tell your doctor if you have any kidney or liver diseases. You should also tell your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses of Parexel Plus Tablet

Benefits of Parexel Plus Tablet

In Treatment of Irritable bowel syndrome

Irritable bowel syndrome is a chronic (long-term) inflammatory disease of the large intestine (colon) that usually needs long term management. This can lead to bleeding, frequent diarrhea, bloating, flatulence, cramps and stomach pain. Parexel Plus 5mg/2.5mg Tablet relaxes the muscles in your stomach and gut(intestine) and relieves these symptoms effectively. Usually, it is used along with other medicines for the management of your condition.
Continue taking it for as long as the doctor may advise you to. You need to take this medicine regularly to get the most out of it. Take a fiber-rich diet, avoid oily or spicy food and drink plenty of fluids while taking it to make sure you stay hydrated.

Side effects of Parexel Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Parexel Plus

  • Sleepiness
  • Nausea
  • Constipation
  • Memory impairment
  • Dizziness
  • Blurred vision
  • Dryness in mouth
  • Difficulty in urination
  • Impaired coordination
  • Depression

How to use Parexel Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Parexel Plus 5mg/2.5mg Tablet is to be taken empty stomach.

How Parexel Plus Tablet works

Parexel Plus 5mg/2.5mg Tablet is a combination of two medicines: Chlordiazepoxide and Clidinium. Chlordiazepoxide is a benzodiazepine. It works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain. Clidinium works by relaxing the muscles in your stomach and gut (intestine). It stops sudden muscle contractions (spasms) which in turn relieves cramps, pain, bloating, and discomfort.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Parexel Plus 5mg/2.5mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Parexel Plus 5mg/2.5mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Parexel Plus 5mg/2.5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Parexel Plus 5mg/2.5mg Tablet may cause side effects which could affect your ability to drive.
As Parexel Plus 5mg/2.5mg Tablet may make you feel drowsy or affect your concentration and this may affect your ability to drive.
Kidney
CAUTION
Parexel Plus 5mg/2.5mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Parexel Plus 5mg/2.5mg Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Parexel Plus 5mg/2.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Parexel Plus 5mg/2.5mg Tablet may be needed. Please consult your doctor.

What if you forget to take Parexel Plus Tablet?

If you miss a dose of Parexel Plus 5mg/2.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Parexel Plus 5mg/2.5mg Tablet
₹3.73/Tablet
Equirex Tablet
Jagsonpal Pharmaceuticals Ltd
₹7.47/tablet
100% costlier
Normaxin-CC Tablet
Systopic Laboratories Pvt Ltd
₹2.23/tablet
40% cheaper
Spasrax Tablet
Overseas Healthcare Pvt Ltd
₹4.65/tablet
25% costlier
Spasril Tablet
Sun Pharmaceutical Industries Ltd
₹3.83/tablet
3% costlier
Libratex Tablet
Talent India
₹5.82/tablet
56% costlier

Quick tips

  • Parexel Plus 5mg/2.5mg Tablet is prescribed to give relief from the symptoms of irritable bowel syndrome.
  • If you are due to have an operation or any dental treatment, please tell the doctor carrying out the treatment that you are taking Parexel Plus 5mg/2.5mg Tablet. This is because it increases the effects of some anesthetics.
  • Inform your doctor if you have an enlarged prostate gland, glaucoma, or trouble passing urine.
  • Inform your doctor if you are pregnant or breastfeeding.
  • If you are 65 or older, use Parexel Plus 5mg/2.5mg Tablet with care. You could have more side effects.
  • Parexel Plus 5mg/2.5mg Tablet is prescribed to give relief from the symptoms of irritable bowel syndrome.
  • If you are due to have an operation or any dental treatment, please tell the doctor carrying out the treatment that you are taking Parexel Plus 5mg/2.5mg Tablet. This is because it increases the effects of some anesthetics.
  • Inform your doctor if you have an enlarged prostate gland, glaucoma, or trouble passing urine.
  • Inform your doctor if you are pregnant or breastfeeding.
  • If you are 65 or older, use Parexel Plus 5mg/2.5mg Tablet with care. You could have more side effects.

Fact Box

Habit Forming
Yes
Therapeutic Class
GASTRO INTESTINAL

Patient concerns

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Restless leg syndrome with irritable bowel syndrome
Dr. Pushkar Mani
Physician
take cobadex czs once daily for 1 monthevion 400 mg once daily for 1 month
I have irritable bowel syndrome
Dr. Deepak Kumar Soni
Ayurveda
https://goo.gl/forms/5QhDt8ZurRhhcjvD2 Kindly fill the health information so that I can advice best products to you thanks
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FAQs

Can the use of Parexel Plus 5mg/2.5mg Tablet cause physical dependence?

Yes, Parexel Plus 5mg/2.5mg Tablet may cause physical dependence as it contains Chlordiazepoxide as one of the ingredients. Physical dependence is defined as the occurrence of a withdrawal reaction following sudden stoppage of the drug or a decrease in dose. Consult your doctor before taking this medicine or if you need to make any change in the dose.

Are there any specific contraindications associated with the use of Parexel Plus 5mg/2.5mg Tablet?

The use of Parexel Plus 5mg/2.5mg Tablet is not recommended to patients with known allergy to any of the components or excipients of Parexel Plus 5mg/2.5mg Tablet. Its use is also not advisable in patients of glaucoma, benign prostate enlargement and bladder neck obstruction.

What precautions do I need to take while using Parexel Plus 5mg/2.5mg Tablet?

Parexel Plus 5mg/2.5mg Tablet should not be taken along with opioids-like substances as it contains chlordiazepoxide. Use of opioids along with chlordiazepoxide may cause excessive sedation (state of calm or sleep), respiratory depression and eventually coma or death. Inform your doctor about all the medicines that you are taking if you are advised to take Parexel Plus 5mg/2.5mg Tablet.

What are the symptoms of an overdose of Parexel Plus 5mg/2.5mg Tablet?

Both Chlordiazepoxide and Clidinium show different symptoms of overdose. Chlordiazepoxide can cause sleepiness, reflexes, confusion and coma. Clidinium can cause excessive dryness of mouth, blurred vision, urinary hesitancy and constipation. Inform the doctor in case you take a higher dose and any of these symptoms appear.

Can the use of Parexel Plus 5mg/2.5mg Tablet cause sleepiness or drowsiness?

Yes, Parexel Plus 5mg/2.5mg Tablet may make you feel drowsy or sleepy. Do not drive, operate any machines, work at heights, or participate in potentially dangerous activities at the start of your treatment. Inform your doctor if you experience such episodes while you are taking this medicine.

Can the use of Parexel Plus 5mg/2.5mg Tablet cause constipation?

Yes, the use of Parexel Plus 5mg/2.5mg Tablet can cause constipation. Eat high-fiber foods like vegetables, fruits and cereals, and drink plenty of water. Exercise regularly by engaging in activities like swimming, jogging or going for a walk. Consult a doctor if constipation persists for a long duration.

Can I drink alcohol while taking Parexel Plus 5mg/2.5mg Tablet?

No, avoid drinking alcohol while you are taking Parexel Plus 5mg/2.5mg Tablet. Drinking alcohol can increase the risk of side effects like drowsiness or sleepiness.

What are the instructions for storage and disposal of Parexel Plus 5mg/2.5mg Tablet?

Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. MedlinePlus. Chlordiazepoxide+Clidinium. [Accessed 15 Apr. 2019] (online) Available from:External Link
  2. Mayo Clinic. Chlordiazepoxide+Clidinium. [Accessed 15 Apr. 2019] (online) Available from:External Link

Marketer details

Name: A N Pharmacia
Address: 315, 3rd Floor DLF Tower B, Jasola, Delhi -110044
Country of origin: India

NOT FOR SALE
We do not facilitate sale of this product at present

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