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Pantrum-O Tablet is a combination of two medicines which is used in the treatment of nausea and vomiting. It is used only when prescribed by a doctor. This medicine works by controlling the acidity and altering the chemicals in the brain that trigger nausea or vomiting.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 22 Jul 2026 | 01:01 AM (IST)
₹70.7 MRP ₹76.888% off 
 
 
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Pantrum-O Tablet image
Pantrum-O Tablet image

Product introduction

Pantrum-O Tablet should be taken in the dose and duration advised by your doctor. Take it on an empty stomach, but try taking it at a fixed time each day. Remember you should not stop taking the medication suddenly without talking to your doctor. In case you vomit within one hour of taking a dose, then take another dose and avoid heavy meals throughout the day. Before taking this medicine, it is better to inform your doctor if you have any liver disease as the dose of your medicine may need adjustment. Your doctor may regularly monitor your liver enzymes, especially when the medicine is prescribed for a long time.

It is a well-tolerated and safe medicine and has a very low incidence of any harmful effects. But, it may cause certain side effects like constipation, stomach pain, fatigue, headache, flatulence, and flushing of skin. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.

This medicine may cause diarrhea, so it is better to take plenty of fluids while taking this medicine as it may help prevent dehydration. However, it is better to consult your doctor if you get watery diarrhea with fever or stomach pain that does not go away. Dizziness and sleepiness may also occur, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

Uses of Pantrum-O Tablet

Benefits of Pantrum-O Tablet

Nausea
Pantrum-O Tablet blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused due to some medicines or cancer treatment. This medicine helps you recover more comfortably from cancer treatments such as radiation therapy or chemotherapy. It is also effective at preventing nausea and vomiting after an operation (in adults only). The dose will depend on what you are being treated for but always take this medicine as it is prescribed.

Side effects of Pantrum-O Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pantrum-O
  • Diarrhea
  • Constipation
  • Stomach pain
  • Fatigue
  • Headache
  • Flatulence
  • Dizziness
  • Flushing of skin

How to use Pantrum-O Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pantrum-O Tablet is to be taken on an empty stomach.

How Pantrum-O Tablet works

Pantrum-O Tablet is a combination of two medicines: Pantoprazole and Ondansetron.

Quick tips

  • Pantrum-O Tablet helps treat nausea and vomiting.
  • Take it one hour before meal, preferably in the morning.
  • It is fast-acting and starts working within 30 minutes.
  • If you vomit within one hour of taking a dose, take another dose.
  • Avoid heavy meals and sip water regularly while taking this medicine.
  • Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.

Safety advice

Alcohol

Alcohol

SAFE
Consuming alcohol with Pantrum-O Tablet does not usually cause any harmful side effects.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Pantrum-O Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CAUTION
Pantrum-O Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Pantrum-O Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Pantrum-O Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
However, inform your doctor if you have an underlying kidney disease. Limited information is available in patients taking this medicine for more than one day.
Liver

Liver

CAUTION
Pantrum-O Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Fact Box

Habit Forming

No

Therapeutic Class

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Integral Lifesciences
Address: 377, SCF First floor Motor Market, Manimajra, Chandigarh, Haryana 160101

Vendor Details

Country of origin: India
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