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Pacigrip D 5mg/250mg Tablet

Domperidone (5mg)+ Paracetamol (250mg)
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Pacigrip D 5mg/250mg Tablet is used to relieve migraine headaches and to treat nausea and vomiting associated with it. This medicine may also be used in ailments where fever is accompanied by vomiting.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 23 Dec 2025 | 12:37 PM (IST)
₹57.8 MRP ₹62.818% off 
 
 
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Pacigrip D 5mg/250mg Tablet image
Pacigrip D 5mg/250mg Tablet image

Your child’s medicine at a glance

Give Pacigrip D 5mg/250mg Tablet to your child orally, preferably 30 minutes before meals. Stick to the dose, time, and way prescribed by your doctor as that depends on your child’s clinical condition, body weight, and age.  In case your child vomits within 30 minutes of taking this medicine, let the child calm down, and then repeat the dose.

Pacigrip D 5mg/250mg Tablet should be given at the first sign of a migraine attack. If symptoms persist, further doses may be given but a gap of 4 hours must be maintained between each dose. However, never exceed the total dose that has been prescribed for a day.

Diarrhea, rash, restlessness, and drowsiness are some of the common yet temporary side effects of this medicine. Make sure to report to your child’s doctor if the side effects persist or become bothersome for your child.

Before giving this medicine to your child, let the doctor know if your child has had any previous episodes of medicine allergy, metabolic disorder, liver impairment, kidney malfunction, asthma, or blood disorder. This information is critical for dose alterations and for planning your child’s overall treatment.

Uses of Pacigrip D 5mg/250mg Tablet in children

Benefits of Pacigrip D 5mg/250mg Tablet for your child

Treatment of Migraine
Pacigrip D 5mg/250mg Tablet is a combination of medicines that helps prevent migraine by changing the way that your nerves receive pain signals. It also blocks the action of chemicals in the body that can make you feel or be sick. This treats as well as prevents nausea or vomiting effectively. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.

Side effects of Pacigrip D 5mg/250mg Tablet in children

Pacigrip D 5mg/250mg Tablet does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Pacigrip D
  • Restlessness
  • Diarrhea
  • Rash
  • Drowsiness

How can I give Pacigrip D 5mg/250mg Tablet to my child?

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pacigrip D 5mg/250mg Tablet is to be taken on an empty stomach.

How Pacigrip D Tablet works

Pacigrip D 5mg/250mg Tablet contains two medicines: Domperidone and Paracetamol. Domperidone is an antiemetic that works on the vomiting center in the brain. It also increases the movement of the muscles of the stomach and intestines, allowing food to move more easily through the stomach. This prevents nausea and vomiting caused due to migraines. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer) which blocks the release of certain chemical messengers that cause the pain associated with migraine.

Quick tips

  • If diarrhea develops as a side effect, encourage your child to drink plenty of fluids.
  • Never give any other medicines containing paracetamol along with this medicine as that may lead to serious side effects.
  • Do not alter the dose by yourself as it can result in unwanted side effects in your child.
  • Do not mix Pacigrip D 5mg/250mg Tablet with any herbal or ayurvedic preparations as it will not be effective.
  • Stop the medicine and report to the doctor on an immediate basis if your child exhibits side effects such as itching, breathing difficulty, and swelling of the face soon after taking Pacigrip D 5mg/250mg Tablet.
  • Pacigrip D 5mg/250mg Tablet helps to ease the pain you feel during a migraine headache as well as helps to stop you from feeling sick.
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • Inform your doctor if you are taking any pain relief medicine.
  • Pacigrip D 5mg/250mg Tablet can only decrease the number and severity of attacks but may not completely stop them.
  • Some tips that may help avoid a migraine attack:
    1. Have your meals at the same time every day.
    2. Avoid bright lights and extreme temperatures.
    3. Avoid loud music and noisy places.
    4. Avoid chocolates,  cheese, processed food, alcohol, and smoking.
    5. Get sufficient sleep and avoid stress.

Safety advice

Kidney

Kidney

SAFE IF PRESCRIBED
Pacigrip D 5mg/250mg Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
However, dose adjustments may be required in severe kidney disease. Please consult with your child's doctor before giving the medicine to your child.
Liver

Liver

CAUTION
Pacigrip D 5mg/250mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
However, the use of Pacigrip D 5mg/250mg Tablet is not recommended in children with severe liver disease and active liver disease.

Frequently asked questions

Children who have a recent history of gut surgery, have gastrointestinal obstruction or perforation, suffer from epilepsy, or are allergic to any of the ingredients of Pacigrip D 5mg/250mg Tablet should avoid taking this medicine.
Children who are malnourished, suffering from a liver or kidney disease, heart disease, and electrolyte disturbances should remain cautious before taking Pacigrip D 5mg/250mg Tablet. Also, children on antipsychotic medicines and those who have a history of atopic allergies such as hay fever, eczema, or asthma should consult the doctor before consuming Pacigrip D 5mg/250mg Tablet. Always, consult your child’s doctor before giving Pacigrip D 5mg/250mg Tablet in such cases.
Excess intake of Pacigrip D 5mg/250mg Tablet is dangerous as it contains paracetamol which can cause serious liver damage (hepatotoxicity) and CNS side effects. Never give more than the prescribed dose to your child as it will not give fast relief rather it would result in serious adverse effects and can worsen your child’s condition.
Keep this medicine at room temperature in a dry place beyond the reach of the children.
Pacigrip D 5mg/250mg Tablet can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Pacigrip D 5mg/250mg Tablet. Also, check with your child’s doctor before giving any medicine to your child.

Fact Box

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NEURO CNS
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Werke Healthcare
Address: Plot No 406 Industrial Area Panchkula-134109, Haryana, India

Vendor Details

Country of origin: India
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