


Pacigrip D 5mg/250mg Tablet
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 23 Dec 2025 | 12:37 PM (IST)
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General Information



Your child’s medicine at a glance
Give Pacigrip D 5mg/250mg Tablet to your child orally, preferably 30 minutes before meals. Stick to the dose, time, and way prescribed by your doctor as that depends on your child’s clinical condition, body weight, and age. In case your child vomits within 30 minutes of taking this medicine, let the child calm down, and then repeat the dose.
Pacigrip D 5mg/250mg Tablet should be given at the first sign of a migraine attack. If symptoms persist, further doses may be given but a gap of 4 hours must be maintained between each dose. However, never exceed the total dose that has been prescribed for a day.
Diarrhea, rash, restlessness, and drowsiness are some of the common yet temporary side effects of this medicine. Make sure to report to your child’s doctor if the side effects persist or become bothersome for your child.
Before giving this medicine to your child, let the doctor know if your child has had any previous episodes of medicine allergy, metabolic disorder, liver impairment, kidney malfunction, asthma, or blood disorder. This information is critical for dose alterations and for planning your child’s overall treatment.
Uses of Pacigrip D 5mg/250mg Tablet in children
Benefits of Pacigrip D 5mg/250mg Tablet for your child
Pacigrip D 5mg/250mg Tablet is a combination of medicines that helps prevent migraine by changing the way that your nerves receive pain signals. It also blocks the action of chemicals in the body that can make you feel or be sick. This treats as well as prevents nausea or vomiting effectively. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.
Side effects of Pacigrip D 5mg/250mg Tablet in children
- Restlessness
- Diarrhea
- Rash
- Drowsiness
How can I give Pacigrip D 5mg/250mg Tablet to my child?
How Pacigrip D Tablet works
Quick tips
- If diarrhea develops as a side effect, encourage your child to drink plenty of fluids.
- Never give any other medicines containing paracetamol along with this medicine as that may lead to serious side effects.
- Do not alter the dose by yourself as it can result in unwanted side effects in your child.
- Do not mix Pacigrip D 5mg/250mg Tablet with any herbal or ayurvedic preparations as it will not be effective.
- Stop the medicine and report to the doctor on an immediate basis if your child exhibits side effects such as itching, breathing difficulty, and swelling of the face soon after taking Pacigrip D 5mg/250mg Tablet.
- Pacigrip D 5mg/250mg Tablet helps to ease the pain you feel during a migraine headache as well as helps to stop you from feeling sick.
- Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
- Inform your doctor if you are taking any pain relief medicine.
- Pacigrip D 5mg/250mg Tablet can only decrease the number and severity of attacks but may not completely stop them.
- Some tips that may help avoid a migraine attack:
- Have your meals at the same time every day.
- Avoid bright lights and extreme temperatures.
- Avoid loud music and noisy places.
- Avoid chocolates, cheese, processed food, alcohol, and smoking.
- Get sufficient sleep and avoid stress.
Safety advice

Kidney
However, dose adjustments may be required in severe kidney disease. Please consult with your child's doctor before giving the medicine to your child.

Liver
However, the use of Pacigrip D 5mg/250mg Tablet is not recommended in children with severe liver disease and active liver disease.
Frequently asked questions
Fact Box
Habit Forming
Therapeutic Class
References
- Royal United Hospitals Bath: NHS. Using Domperidone + Ibuprofen/Aspirin/Paracetamol for Migraine Attacks. 2017. [Accessed 22 Feb. 2021] (online) Available from:
- MacGregor EA, Wilkinson M, Bancroft K. Domperidone plus paracetamol in the treatment of migraine. Cephalalgia. 1993;13(2):124-7. [Accessed 22 Feb. 2021] (online) Available from:
- Ong JJY, De Felice M. Migraine Treatment: Current Acute Medications and Their Potential Mechanisms of Action. Neurotherapeutics 2018;15:274-90. [Accessed 22 Feb. 2021] (online) Available from:




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