


P Gest O Tablet
Pantoprazole (40mg)+ Ondansetron (4mg)
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P Gest O Tablet is a combination of two medicines which is used in the treatment of nausea and vomiting. It is used only when prescribed by a doctor. This medicine works by controlling the acidity and altering the chemicals in the brain that trigger nausea or vomiting.
Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)
Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)
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General Information
Contains
Pantoprazole (40mg)+ Ondansetron (4mg)
Marketer
Asterisk Laboratories India Pvt Ltd
Storage
Store below 30°C
The content is shown in English



Product introduction
P Gest O Tablet should be taken in the dose and duration advised by your doctor. Take it on an empty stomach, but try taking it at a fixed time each day. Remember you should not stop taking the medication suddenly without talking to your doctor. In case you vomit within one hour of taking a dose, then take another dose and avoid heavy meals throughout the day. Before taking this medicine, it is better to inform your doctor if you have any liver disease as the dose of your medicine may need adjustment. Your doctor may regularly monitor your liver enzymes, especially when the medicine is prescribed for a long time.
It is a well-tolerated and safe medicine and has a very low incidence of any harmful effects. But, it may cause certain side effects like constipation, stomach pain, fatigue, headache, flatulence, and flushing of skin. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.
This medicine may cause diarrhea, so it is better to take plenty of fluids while taking this medicine as it may help prevent dehydration. However, it is better to consult your doctor if you get watery diarrhea with fever or stomach pain that does not go away. Dizziness and sleepiness may also occur, so do not drive or do anything that requires mental focus until you know how this medicine affects you.
It is a well-tolerated and safe medicine and has a very low incidence of any harmful effects. But, it may cause certain side effects like constipation, stomach pain, fatigue, headache, flatulence, and flushing of skin. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.
This medicine may cause diarrhea, so it is better to take plenty of fluids while taking this medicine as it may help prevent dehydration. However, it is better to consult your doctor if you get watery diarrhea with fever or stomach pain that does not go away. Dizziness and sleepiness may also occur, so do not drive or do anything that requires mental focus until you know how this medicine affects you.
Uses of P Gest O Tablet
Benefits of P Gest O Tablet
Nausea
P Gest O Tablet blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused due to some medicines or cancer treatment. This medicine helps you recover more comfortably from cancer treatments such as radiation therapy or chemotherapy. It is also effective at preventing nausea and vomiting after an operation (in adults only). The dose will depend on what you are being treated for but always take this medicine as it is prescribed.
P Gest O Tablet blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused due to some medicines or cancer treatment. This medicine helps you recover more comfortably from cancer treatments such as radiation therapy or chemotherapy. It is also effective at preventing nausea and vomiting after an operation (in adults only). The dose will depend on what you are being treated for but always take this medicine as it is prescribed.
Side effects of P Gest O Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of P Gest O
- Diarrhea
- Constipation
- Stomach pain
- Fatigue
- Headache
- Flatulence
- Dizziness
- Flushing of skin
How to use P Gest O Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. P Gest O Tablet is to be taken on an empty stomach.
How P Gest O Tablet works
P Gest O Tablet is a combination of two medicines: Pantoprazole and Ondansetron.
All substitutes for P Gest O Tablet
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- P Gest O Tablet helps treat nausea and vomiting.
- Take it one hour before meal, preferably in the morning.
- It is fast-acting and starts working within 30 minutes.
- If you vomit within one hour of taking a dose, take another dose.
- Avoid heavy meals and sip water regularly while taking this medicine.
- Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
Safety advice

Alcohol
CAUTION
Alcohol should be used with caution while taking P Gest O Tablet.

Pregnancy
SAFE IF PRESCRIBED
P Gest O Tablet is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding
SAFE IF PRESCRIBED
P Gest O Tablet may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving
UNSAFE
P Gest O Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
SAFE IF PRESCRIBED
P Gest O Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
However, inform your doctor if you have an underlying kidney disease. Limited information is available in patients taking this medicine for more than one day.
However, inform your doctor if you have an underlying kidney disease. Limited information is available in patients taking this medicine for more than one day.

Liver
SAFE IF PRESCRIBED
P Gest O Tablet is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.
Fact Box
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Asterisk Laboratories India Pvt Ltd
Address: S.C.O 867 Basement N.A.C Manimajra, Chandigarh-160101
Address: S.C.O 867 Basement N.A.C Manimajra, Chandigarh-160101
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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