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Oxin PS Tablet is a combination medicine that helps in relieving pain. It works by blocking the release of certain chemical messengers that cause pain, inflammation, and fever in various conditions. It also promotes healing at the site of inflammation.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 14 Apr 2026 | 04:58 PM (IST)
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General Information

Contains

Nimesulide (100mg)+ Paracetamol (500mg)+ Serratiopeptidase (15mg)

Marketer

Synokem Pharmaceuticals Ltd

Storage

Store below 30°C
The content is shown in English
Oxin PS Tablet image
Oxin PS Tablet image

Product introduction

Oxin PS Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, diarrhea, stomach pain, increased liver enzymes, and heartburn. If any of these side effects bother you or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.


Note: As per the Ministry of Health and Family Welfare, Oxin PS Tablet is banned for children under 12 years of age.

Uses of Oxin PS Tablet

Benefits of Oxin PS Tablet

Pain relief
Pain from injury, swelling, or inflammation can interfere with daily activities and overall comfort. Oxin PS Tablet helps to reduce pain, fever, and swelling. It provides fast and effective relief, helping individuals move more comfortably and recover faster from painful conditions.

Side effects of Oxin PS Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Oxin PS
  • Nausea
  • Heartburn
  • Vomiting
  • Diarrhea
  • Stomach pain
  • Increased liver enzymes

How to use Oxin PS Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Oxin PS Tablet should be taken with or after food.

How Oxin PS Tablet works

Oxin PS Tablet is a combination of three medicines: Nimesulide, Paracetamol and Serratiopeptidase. Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers in the brain that cause pain and fever. Serratiopeptidase is an enzyme which works by breaking down abnormal proteins at the site of inflammation, and promotes healing.

All substitutes for Oxin PS Tablet

For information purposes only. Consult a doctor before taking any medicine.

Denim Plus 100 mg/500 mg/15 mg Tablet

by Maneesh Pharmaceuticals Ltd
₹4.73/tablet
15% cheaper
<h3 class=bodySemiBold>Denim Plus 100 mg/500 mg/15 mg Tablet</h3>

Leemoflam 100mg/500mg/15mg Tablet

by LeeMed Pharmaceuticals
₹5.53/tablet
1% cheaper
<h3 class=bodySemiBold>Leemoflam 100mg/500mg/15mg Tablet</h3>

Genulid PS 100mg/500mg/15mg Tablet

by Vrinda Life
₹7/tablet
25% costlier
<h3 class=bodySemiBold>Genulid PS 100mg/500mg/15mg Tablet</h3>

Quick tips

  • You have been prescribed this combination medicine for relieving pain and inflammation.
  • Take it with food to avoid getting an upset stomach.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how Oxin PS Tablet affects you.
  • Avoid consuming alcohol when taking Oxin PS Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
  • Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Oxin PS Tablet.
Pregnancy

Pregnancy

UNSAFE
Oxin PS Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Oxin PS Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Oxin PS Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Oxin PS Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Oxin PS Tablet is not recommended in patients with severe kidney disease.
Liver

Liver

UNSAFE
Oxin PS Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Oxin PS Tablet is usually used for short-term pain relief and can be discontinued if there is no pain. However, it should be continued if advised by the doctor.
Oxin PS Tablet contains nimesulide and paracetamol, and both these medicines are known to cause harm to the liver especially in doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with underlying liver disease.
No, taking a higher than the recommended dose of Oxin PS Tablet can lead to increased chances of side effects. If the recommended dosage does not relieve your symptoms or you experience increased severity of pain, please consult your doctor for re-evaluation.
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. European Medicine Agency. Nimesulide; 2004. [Accessed 02 Apr. 2019] (online) Available from:
  2. Bhagat S, Agarwal M, Roy V. Serratiopeptidase: A systematic review of the existing evidence. Int J Surg. 2013;11(3):209-17. [Accessed 02 Apr. 2019] (online) Available from:
  3. ScienceDirect. Nimesulide. [Accessed 02 Apr. 2019] (online) Available from:
  4. ScienceDirect. Paracetamol. [Accessed 02 Apr. 2019] (online) Available from:
  5. PubChem. Serratiopeptidase. [Accessed 02 Apr. 2019] (online) Available from:
  6. Nimesulide, Paracetamol, and Serratiopeptidase. Panchkula, Haryana: Servocare; [Accessed 14 Apr. 2026] (online). Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Synokem Pharmaceuticals Ltd
Address: 14/486, Sunder Vihar, Outer Ring , Road, Paschim Vihar, New, Delhi-110 087, INDIA

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Oxin PS Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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