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Oxyrute Cream is a combination medicine used in the treatment of piles. It relieves the pain, swelling, itching, and discomfort associated with the passing of stools in people who suffer from problems in the anal area.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 25 May 2026 | 12:24 PM (IST)
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50 gm Rectal Cream
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Gurgaon
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Oxyrute Cream
Oxyrute Cream
tube of 50 gm Rectal Cream
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by Fourrts India Laboratories Pvt Ltd
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Product introduction

Oxyrute Cream should be used in the dose and duration as directed by your doctor. Clean and dry the affected area before applying this medicine. Make sure to wash your hands thoroughly before and after applying this medicine. Do not use your finger to apply this medicine. Do not stop using it suddenly without talking to your doctor, as it may lead to worsening of your condition.

Using of this medicine may cause application site reactions (burning, irritation, itching, and redness). These are temporary and usually resolves on with time. You should consult your doctor if any of these do not resolve with time and persists for a longer duration.

Avoid getting it into your eyes, nose or mouth. If accidental exposure occurs, wash your eyes with water and seek immediate medical attention. You should stop using it and inform your doctor if you notice worsening of the infection or if you develop increased redness and irritation.

Uses of Oxyrute Rectal Cream

Benefits of Oxyrute Rectal Cream

Treatment of Piles
Oxyrute Cream reduces discomfort, improves blood flow, decreases leakage as well as rupture of veins and prevents clotting of blood. This effectively relieves pain, swelling, irritation or itching caused due to piles. It also has antioxidant properties that promote healing in plies (hemorrhoids). Always use the medicine as prescribed to get maximum benefit. Make sure to avoid spicy, oil-rich food and take plenty of fibers to aid in digestion and ensure speedy recovery.

Side effects of Oxyrute Rectal Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Oxyrute
  • Application site reactions (burning, irritation, itching and redness)

How to use Oxyrute Rectal Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor.

How Oxyrute Rectal Cream works

Oxyrute Cream is a combination of six medicines: Lidocaine, Calcium Dobesilate, Hydrocortisone, Phenylephrine, Zinc Oxide and Troxerutin. Lidocaine is a local anesthetic which blocks pain signals from the nerves to brain thereby decreasing pain sensation. Calcium Dobesilate and Troxerutin are vasoprotective medicines which strengthen the blood vessels in the affected area.and promoting healing. Hydrocortisone is a steroid which reduces redness, itching, and swelling. Phenylephrine is a decongestant that shrinks the swollen blood vessels to further relieve itching and irritation in piles. Zinc Oxide has astringent and antiseptic action.

Quick tips

  • Oxyrute Cream is prescribed for the treatment of piles.
  • Apart from using Oxyrute Cream, you can indulge in warm baths. It may help soothe the area and thus may ease the pain.
  • Don't ignore the feeling of needing to pass stools. Some people suppress this feeling and put off going to the toilet until later. This may result in bigger and harder stools forming that are more difficult to pass later.
  • Do not take any oral laxative along with Oxyrute Cream without consulting your doctor.
  • Sometimes certain medicines like iron tablets, antibiotics might cause constipation. Inform your doctor if you are taking any of them.
  • A fiber-rich diet (wholegrain bread and cereals, fruit and green leafy vegetables) with six to eight full glasses of water each day and daily exercise are important in maintaining healthy bowel function.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Oxyrute Cream during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Oxyrute Cream during breastfeeding is not available. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

SAFE IF PRESCRIBED
Oxyrute Cream is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver

Liver

SAFE IF PRESCRIBED
Oxyrute Cream is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Frequently asked questions

Oxyrute Cream is used to relieve pain, itching, swelling, and discomfort caused by hemorrhoids, anal fissures, and other rectal issues.
Yes, Oxyrute Cream is formulated for application around and inside the anal area to relieve symptoms from both internal and external hemorrhoids.<br>
Oxyrute Cream should be used only for the duration recommended by your doctor, usually not exceeding 1 to 2 weeks, to avoid skin irritation or other side effects.
Oxyrute Cream is often used to reduce bleeding and aid healing, but consult your doctor if bleeding is heavy or persistent.
The exact time Oxyrute Cream takes to provide relief is not known. However, many users experience numbness and reduced pain within minutes, with swelling and irritation improving over several days.
Yes, Oxyrute Cream relieves itching and discomfort due to its anti-inflammatory and soothing ingredients.

Fact Box

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

References

  1. Drasner K. Local Anesthetics. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 439-450.
  2. Catterall WA, Mackie K. Local Anesthetics. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 13th ed. New York, NY: McGraw-Hill Education; 2018. pp. 405-419.
  3. Chrousos GP. Adrenocorticosteroids & Adrenocortical Antagonists. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 681-697.
  4. Westfall TC, Macarthur H, Westfall DP. Adrenergic Agonists and Antagonists. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 13th ed. New York, NY: McGraw-Hill Education; 2018. pp. 191-223.
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User feedback

Once A Day
67%
Twice A Day
25%
Thrice A Day
8%
Piles
82%
Others
18%
Average
53%
Poor
27%
Excellent
20%
No Side Effect
85%
Application site reactions (burning, irritation, itching and redness)
15%
With or without food
80%
Empty stomach
20%
Average
74%
Not Expensive
19%
Expensive
7%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Fourrts India Laboratories Pvt Ltd
Address: Plot No.: 1, Fourrts Avenue, Annai Indira nagar, Okkiyam thoraipakkam, Chennai - 600 097

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Oxyrute Cream. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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